Modeling the Residence Time Distribution of Integrated Continuous Bioprocesses

Continuous integrated antibody precipitation with two-stage tangential flow microfiltration enables constant mass flow

(2019) Daniel Burgstaller et al.   BIOTECHNOLOGY AND BIOENGINEERING

Continuous solvent/detergent virus inactivation using a packed-bed reactor

(2019) Duarte L. Martins et al.   Biotechnology Journal

Experimental Evaluation of the Impact of Intrinsic Process Parameters on the Performance of a Continuous Chromatographic Polishing Unit (MCSGP)

(2019) Sebastian Vogg et al.   Biotechnology Journal

Continuous manufacturing of a pharmaceutical cream: Investigating continuous powder dispersing and residence time distribution (RTD)

(2019) N. Bostijn et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Continuous Precipitation for Monoclonal Antibody Capture Using Countercurrent Washing by Microfiltration

(2019) Zhao Li et al.   BIOTECHNOLOGY PROGRESS

A narrow residence time incubation reactor for continuous virus inactivation based on packed beds

(2019) Jure Senčar et al.   New Biotechnology

Challenges and opportunities in biopharmaceutical manufacturing control

(2018) Moo Sun Hong et al.   COMPUTERS & CHEMICAL ENGINEERING

Continuous integrated manufacturing of therapeutic proteins

(2018) Daniel Johannes Karst et al.   CURRENT OPINION IN BIOTECHNOLOGY

Integrated flow-through purification for therapeutic monoclonal antibodies processing

(2018) Takamitsu Ichihara et al.   mAbs

Progression of continuous downstream processing of monoclonal antibodies: current trends and challenges

(2018) Balaji Somasundaram et al.   BIOTECHNOLOGY AND BIOENGINEERING

Commentary: Continuous virus inactivation: How to generate a plug flow

(2018) Alois Jungbauer   Biotechnology Journal

Transfer of a three step mAb chromatography process from batch to continuous: Optimizing productivity to minimize consumable requirements

(2017) Xhorxhi Gjoka et al.   JOURNAL OF BIOTECHNOLOGY

Continuous cell flocculation for recombinant antibody harvesting

(2017) Daniel Burgstaller et al.   JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY

Continuous desalting of refolded protein solution improves capturing in ion exchange chromatography: A seamless process

(2017) Nicole Walch et al.   Biotechnology Journal

Continuous counter-current chromatography for capture and polishing steps in biopharmaceutical production

(2016) Fabian Steinebach et al.   Biotechnology Journal

Continuous counter-current chromatography for capture and polishing steps in biopharmaceutical production

(2016) Fabian Steinebach et al.   Biotechnology Journal

Optimal model-based design of the twin-column CaptureSMB process improves capacity utilization and productivity in protein A affinity capture

(2015) Daniel Baur et al.   Biotechnology Journal

Continuous precipitation of IgG from CHO cell culture supernatant in a tubular reactor

(2015) Nikolaus Hammerschmidt et al.   Biotechnology Journal

End-to-end integrated fully continuous production of recombinant monoclonal antibodies

(2015) Rahul Godawat et al.   JOURNAL OF BIOTECHNOLOGY

Optimal model-based design of the twin-column CaptureSMB process improves capacity utilization and productivity in protein A affinity capture

(2015) Daniel Baur et al.   Biotechnology Journal

Continuous precipitation of IgG from CHO cell culture supernatant in a tubular reactor

(2015) Nikolaus Hammerschmidt et al.   Biotechnology Journal

Continuous purification of antibodies from cell culture supernatant with aqueous two-phase systems: From concept to process

(2012) Paula A. J. Rosa et al.   Biotechnology Journal

A review of the Residence Time Distribution (RTD) applications in solid unit operations

(2012) Yijie Gao et al.   POWDER TECHNOLOGY

Continuous aqueous two-phase extraction of human antibodies using a packed column

(2011) P.A.J. Rosa et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Residence time distribution in holding tubes using generalized convection model and numerical convolution for non-ideal tracer detection

(2010) Carola G.C.C. Gutierrez et al.   JOURNAL OF FOOD ENGINEERING