Multiplexed gene transfer to a human T-cell line by combining Sleeping Beauty transposon system with methotrexate selection

Efficient selection of genetically modified human T cells using methotrexate-resistant human dihydrofolate reductase

(2013) M Jonnalagadda et al.   GENE THERAPY

Engineering Human T Cells for Resistance to Methotrexate and Mycophenolate Mofetil as an In Vivo Cell Selection Strategy

(2013) Mahesh Jonnalagadda et al.   PLoS One

Efficient Sleeping Beauty DNA Transposition From DNA Minicircles

(2013) Nynne Sharma et al.   Molecular Therapy-Nucleic Acids

Tumor-targeted T cells modified to secrete IL-12 eradicate systemic tumors without need for prior conditioning

(2012) H. J. Pegram et al.   BLOOD

Imaging of genetically engineered T cells by PET using gold nanoparticles complexed to Copper-64

(2012) Parijat Bhatnagar et al.   Integrative Biology

Chimeric Antigen Receptor T Cells Shape Myeloid Cell Function within the Tumor Microenvironment through IFN-  and GM-CSF

(2012) P. Spear et al.   JOURNAL OF IMMUNOLOGY

Combination of Sleeping Beauty transposition and chemically induced dimerization selection for robust production of engineered cells

(2012) Nataly Kacherovsky et al.   NUCLEIC ACIDS RESEARCH

Antitumor activity and long-term fate of chimeric antigen receptor-positive T cells in patients with neuroblastoma

(2011) C. U. Louis et al.   BLOOD

Nonviral Gene Delivery with the Sleeping Beauty Transposon System

(2011) Zoltán Ivics et al.   HUMAN GENE THERAPY

The Sleeping Beauty transposon system: a non-viral vector for gene therapy

(2011) E. L. Aronovich et al.   HUMAN MOLECULAR GENETICS

Chimeric Antigen Receptor–Modified T Cells in Chronic Lymphoid Leukemia

(2011) David L. Porter et al.   NEW ENGLAND JOURNAL OF MEDICINE

T Cells with Chimeric Antigen Receptors Have Potent Antitumor Effects and Can Establish Memory in Patients with Advanced Leukemia

(2011) M. Kalos et al.   Science Translational Medicine

Tumor-Specific CD8+ T Cells Expressing Interleukin-12 Eradicate Established Cancers in Lymphodepleted Hosts

(2010) S. P. Kerkar et al.   CANCER RESEARCH

A robust system for production of minicircle DNA vectors

(2010) Mark A Kay et al.   NATURE BIOTECHNOLOGY

Multiplexed transposon-mediated stable gene transfer in human cells

(2010) K. M. Kahlig et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

T lymphocytes coexpressing CCR4 and a chimeric antigen receptor targeting CD30 have improved homing and antitumor activity in a Hodgkin tumor model

(2009) A. Di Stasi et al.   BLOOD

Molecular evolution of a novel hyperactive Sleeping Beauty transposase enables robust stable gene transfer in vertebrates

(2009) Lajos Mátés et al.   NATURE GENETICS

Analyzing real-time PCR data by the comparative CT method

(2008) Thomas D Schmittgen et al.   Nature Protocols