Article
Chemistry, Multidisciplinary
Dmitry Tsurkan, Paul Simon, Christian Schimpf, Mykhaylo Motylenko, David Rafaja, Friedrich Roth, Dmytro S. Inosov, Anna A. Makarova, Izabela Stepniak, Iaroslav Petrenko, Armin Springer, Enrico Langer, Anton A. Kulbakov, Maxim Avdeev, Artur R. Stefankiewicz, Korbinian Heimler, Olga Kononchuk, Sebastian Hippmann, Doreen Kaiser, Christine Viehweger, Anika Rogoll, Alona Voronkina, Valentin Kovalchuk, Vasilii V. Bazhenov, Roberta Galli, Mehdi Rahimi-Nasrabadi, Serguei L. Molodtsov, Yvonne Joseph, Carla Vogt, Denis V. Vyalikh, Martin Bertau, Hermann Ehrlich
Summary: The study focuses on designing new composite materials using extreme biomimetics with the development of a new spongin-atacamite composite material. The structure of the material is confirmed through various experimental techniques, suggesting multifunctional applicability for the development of 3D constructed sensors, catalysts, and antibacterial filter systems.
ADVANCED MATERIALS
(2021)
Article
Engineering, Multidisciplinary
Anita Kubiak, Alona Voronkina, Martyna Pajewska-Szmyt, Martyna Kotula, Bartosz Lesniewski, Alexander Ereskovsky, Korbinian Heimler, Anika Rogoll, Carla Vogt, Parvaneh Rahimi, Sedigheh Falahi, Roberta Galli, Enrico Langer, Maik Foerste, Alexandros Charitos, Yvonne Joseph, Hermann Ehrlich, Teofil Jesionowski
Summary: In this study, spongin from Hippospongia communis was used as a template to develop a new 3D composite containing goethite. The obtained composite showed potential industrial applications and exhibited satisfactory performance in the electrochemical sensing of dopamine in human urine samples.
Article
Materials Science, Characterization & Testing
Sonia Zoltowska, Iwona Koltsov, Krzysztof Alejski, Hermann Ehrlich, Michal Cialkowski, Teofil Jesionowski
Summary: The kinetic parameters of thermal degradation of spongin from Hippospongia communis were evaluated, with the chemical reaction model found to best describe the experimental data and calculated activation energies slightly lower than commercial polyurethane foams. The study provides comprehensive insights into the pyrolysis pathway, mechanism, and outcomes of spongin-based scaffolds with relation to physicochemical characteristics of carbon materials, alongside critical discussion of the results and the physical meaning of the applied approximations.
Article
Biotechnology & Applied Microbiology
Kasun Godigamuwa, Kazunori Nakashima, Sota Tsujitani, Satoru Kawasaki
Summary: The fusion of silicatein with other proteins allows for its catalytic activity under mild conditions, making it suitable for immobilization on materials like chitin. This technique opens up possibilities for the development of novel biocatalytic systems and biosensors in various fields.
BIOPROCESS AND BIOSYSTEMS ENGINEERING
(2021)
Article
Materials Science, Biomaterials
Zhengyun Ling, Jian Zhao, Shiyu Song, Shuwei Xiao, Pengchao Wang, Ziyan An, Zhouyang Fu, Jinpeng Shao, Zhuang Zhang, Weijun Fu, Shenghan Song
Summary: In recent years, hydrogels have gained increasing attention in tissue engineering, and the integration of 3D bioprinting has expanded the range of applications. Gelatin methacrylate (GelMA) is commonly used in 3D bioprinting due to its good biocompatibility, but its low mechanical properties limit its use. In this study, the researchers developed a biomaterial ink composed of GelMA and chitin nanocrystal (ChiNC) to enhance the mechanical properties and printability of GelMA hydrogels, promote cell adhesion and proliferation, enable vascularization, and print complex 3D scaffolds.
REGENERATIVE BIOMATERIALS
(2023)
Review
Chemistry, Multidisciplinary
Mariam Hussain, Ethan I. L. Jull, Richard J. Mandle, Thomas Raistrick, Peter J. Hine, Helen F. Gleeson
Summary: Liquid crystal elastomers combine the properties of conventional elastomers and anisotropic liquid crystals, providing unique attributes with potential applications in biology and biomedicine. Recent advances in LCE synthesis and understanding of their behavior have led to exploration of applications in biomimetics, artificial tissue, biological sensors, and cell scaffolds. Researchers are also interested in using LCEs as a model for morphogenesis, indicating a promising future for LCEs in various biological and biomedical fields.
Article
Biotechnology & Applied Microbiology
Karolyne dos Santos Jorge Sousa, Julia Risso Parisi, Amanda de Souza, Matheus de Almeida Cruz, Rogerio Erbereli, Jonas de Araujo Silva, Giovanna do Espirito Santo, Gustavo Oliva do Amaral, Cintia Cristina Santi Martignago, Carlos Alberto Fortulan, Renata Neves Granito, Ana Claudia Muniz Renno
Summary: The inorganic part of marine sponges, called Biosilica (BS), has osteogenic potential and can consolidate fractures. 3D printing technique is effective for manufacturing tissue engineering scaffolds. This study characterized 3D printed BS scaffolds, evaluated their biological effects in vitro, and investigated their in vivo response using a rat cranial defect model. The results showed that the 3D printed BS scaffolds had favorable physicochemical characteristics, promoted cell viability, and improved bone repair in critical bone defects.
MARINE BIOTECHNOLOGY
(2023)
Article
Materials Science, Multidisciplinary
Iman Sahafnejad-Mohammadi, Sadegh Rahmati, Najmeh Najmoddin, Mahdi Bodaghi
Summary: Previous studies have failed to mimic the gradient structure of natural bone in the design of bone scaffolds. In this study, a biomimetic bone scaffold with Haversian channels was designed to approximate the native bone structure. The influence of incorporating graphene oxide (GO) into polycaprolactone (PCL)-based scaffolds was investigated, and it was found that the addition of GO affected the mechanical properties and biodegradation rates of the scaffolds. Furthermore, cell viability was enhanced in the PCL/GO scaffolds compared to pure PCL scaffolds.
MACROMOLECULAR MATERIALS AND ENGINEERING
(2023)
Article
Engineering, Biomedical
Sean E. Lehman, Joselle M. McCracken, Lou Ann Miller, Sanjaya Jayalath, Ralph G. Nuzzo
Summary: The research focuses on developing a new multi-functional soft material for the growth and directed culturing of cells in the field of 3D printing. The composite material described serves as both a scaffold for cell lines and a plasmonic biosensor for in situ measurements of living cells, providing a tunable, 3D printable plasmonic composite material.
ADVANCED HEALTHCARE MATERIALS
(2021)
Article
Engineering, Biomedical
Teresa Carranza, Jone Uranga, Ainhoa Irastorza, Ander Izeta, Pedro Guerrero, Koro de la Caba
Summary: Novel scaffolds based on natural polymers were developed by combining 3D printing and electrospinning techniques. The 3DP ink was prepared with gelatin and chitin, while the ES ink was prepared with gelatin and poly(vinyl alcohol) (PVA). The combination of these biopolymers resulted in a multilayered scaffold with unique properties suitable for tissue regeneration.
INTERNATIONAL JOURNAL OF BIOPRINTING
(2023)
Article
Chemistry, Physical
Weronika Brzozowska, Myroslav Sprynskyy, Izabela Wojtczak, Przemyslaw Dabek, Michal J. Markuszewski, Andrzej Witkowski, Boguslaw Buszewski
Summary: Diatoms are a large group of microalgae that can synthesize complex structures. This study aims to enhance the optical properties of diatoms by investigating their ability to incorporate titanium into their cell walls.
Review
Chemistry, Multidisciplinary
Nefeli Lagopati, Natassa Pippa, Maria-Anna Gatou, Nefeli Papadopoulou-Fermeli, Vassilis G. Gorgoulis, Maria Gazouli, Evangelia A. Pavlatou
Summary: Aquatic habitats contain diverse species contributing to marine biodiversity, providing a rich source of chemical compounds for biomedical applications. The structural characteristics of marine and aquatic organisms make them promising candidates for tissue engineering in regenerative medicine. This article discusses the biomedical applications of biomaterials derived from seaweeds, marine sponges, arthropods, cnidaria, mollusks, etc., highlighting their sustainability and potential antimicrobial, anti-inflammatory, anti-aging, and anticancer effects.
APPLIED SCIENCES-BASEL
(2023)
Article
Biotechnology & Applied Microbiology
Zhuohui Yang, Chunjuan Wang, Hui Gao, Lurong Jia, Huan Zeng, Liwen Zheng, Chao Wang, Hongmei Zhang, Lizhen Wang, Jinlin Song, Yubo Fan
Summary: In this study, bioactive ceramic scaffolds with different porous gradient structures were designed and fabricated using 3D printing technology. The mechanical and biological properties of the scaffolds were evaluated through compression tests, finite element analysis, and in vitro and in vivo experiments. The results showed that scaffolds with gradually increasing pore size had better osteogenicity, while scaffolds with gradually decreasing pore size had superior biomechanical properties. This research provides basic strategies and concepts for the future design and development of scaffolds for the clinical restoration of alveolar bone defects.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Article
Chemistry, Medicinal
Izabela Dziedzic, Alona Voronkina, Martyna Pajewska-Szmyt, Martyna Kotula, Anita Kubiak, Heike Meissner, Tomas Duminis, Hermann Ehrlich
Summary: Chitin, a polysaccharide found in sponges, plays a crucial role in providing mechanical stability to their unique 3D-structured skeletons. By using a 1% LiOH solution and sonication, researchers were able to extract multilayered, tube-like chitin from cultivated Aplysina aerophoba sponge skeletons. Surprisingly, this extraction method not only isolated chitinous scaffolds but also resulted in their dissolution and the formation of amorphous-like matter. Evaluation of the chitin revealed no differences between the sponge-derived chitin and chitin derived from arthropods, suggesting that lithium ions are responsible for the formation of LiBr and the dissolution of chitin in the sponge.
Article
Chemistry, Multidisciplinary
Weronika Brzozowska, Izabela Wojtczak, Myroslav Sprynskyy, BOGUStAW Buszewski
Summary: This review provides an overview of the properties, applications, and methods for the production of SiO2 structures under laboratory and pilot plant conditions, with a total of 54 references.
PRZEMYSL CHEMICZNY
(2021)
Review
Food Science & Technology
Esmaeil Sheibani, Asieh Hosseini, Ali Sobhani Nasab, Kourosh Adib, Mohammad Reza Ganjali, Seied Mahdi Pourmortazavi, Farhad Ahmadi, Elnaz Marzi Khosrowshahi, Somayeh Mirsadeghi, Mehdi Rahimi-Nasrabadi, Hermann Ehrlich
Summary: This paper reviews the reports on the extraction and determination of organic and inorganic analytes using polysaccharide-based biopolymers as solid phase sorbents for sample preparation. It explores the suitability of biopolymers as a choice for sample preparation methods.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Article
Chemistry, Applied
Ahmet Kertmen, Izabela Dziedzic, Hermann Ehrlich
Summary: Cationic chitosan, as a derivative of chitin, has specific physicochemical properties, biodegradability, and biocompatibility, and is widely used in patents related to biomedical, material science, biotechnology, and chemical fields.
CARBOHYDRATE POLYMERS
(2023)
Article
Chemistry, Medicinal
Krzysztof Nowacki, Maciej Galinski, Andriy Fursov, Alona Voronkina, Heike Meissner, Iaroslav Petrenko, Allison L. Stelling, Hermann Ehrlich
Summary: In this study, chitinous matrices were successfully isolated from three species of marine sponges using an electrochemical method, which showed advantages in reducing treatment time. Further investigation revealed that the electrochemical isolation process obtained chitinous scaffolds with well-preserved spatial structure and it can compete with other techniques.
Article
Environmental Sciences
Hamed Mohtasham, Mojtaba Rostami, Behnam Gholipour, Amir Mohammad Sorouri, Hermann Ehrlich, Mohmmad Reza Ganjali, Sadegh Rostamnia, Mehdi Rahimi-Nasrabadi, Abdollah Salimi, Rafael Luque
Summary: Co3O4 NPs@N-PC materials were synthesized through one-pot pyrolysis of ZIF-67 powder and subsequent oxidation under N2 and air atmospheres, respectively. The Co3O4 NPs@N-PC exhibited excellent catalytic activity and activation of PMS for the degradation of SMZ. The mechanism of Co2+/Co3+ redox system before and after PMS activation was investigated using XPS analysis.
Article
Chemistry, Medicinal
Izabela Dziedzic, Alona Voronkina, Martyna Pajewska-Szmyt, Martyna Kotula, Anita Kubiak, Heike Meissner, Tomas Duminis, Hermann Ehrlich
Summary: Chitin, a polysaccharide found in sponges, plays a crucial role in providing mechanical stability to their unique 3D-structured skeletons. By using a 1% LiOH solution and sonication, researchers were able to extract multilayered, tube-like chitin from cultivated Aplysina aerophoba sponge skeletons. Surprisingly, this extraction method not only isolated chitinous scaffolds but also resulted in their dissolution and the formation of amorphous-like matter. Evaluation of the chitin revealed no differences between the sponge-derived chitin and chitin derived from arthropods, suggesting that lithium ions are responsible for the formation of LiBr and the dissolution of chitin in the sponge.
Article
Chemistry, Analytical
Faezeh Shahdost-Fard, Shahin Faridfar, Amir Homayoun Keihan, Mohammad Aghaei, Iaroslav Petrenko, Farhad Ahmadi, Hermann Ehrlich, Mehdi Rahimi-Nasrabadi
Summary: This study synthesized a nanocomposite of spongin and copper tungsten oxide hydroxide and developed a high-performance aptasensing platform. The nanocomposite enhanced electron transfer and increased electrochemical sites. The aptasensor, fabricated by loading thiolated aptamer on the nanocomposite surface, successfully detected Staphylococcus aureus and showed high selectivity.
Article
Chemistry, Analytical
Sedigheh Falahi, Sepideh Falahi, Mashaalah Zarejousheghani, Hermann Ehrlich, Yvonne Joseph, Parvaneh Rahimi
Summary: Gallic acid (GA) is an important polyphenol with various biological effects, making it widely used in multiple industries. Electrochemical sensors are a simple, fast, and sensitive method for GA quantitation due to its electroactive nature. A high-performance bio-nanocomposite sensor was developed using spongin as a 3D polymer, atacamite, and multi-walled carbon nanotubes (MWCNTs), showing excellent response and electrochemical features for GA oxidation.
Article
Engineering, Multidisciplinary
Alona Voronkina, Eliza Romanczuk-Ruszuk, Robert E. Przekop, Pawel Lipowicz, Ewa Gabriel, Korbinian Heimler, Anika Rogoll, Carla Vogt, Milosz Frydrych, Pawel Wienclaw, Allison L. Stelling, Konstantin Tabachnick, Dmitry Tsurkan, Hermann Ehrlich
Summary: Structural bioinspiration is a current trend in modern material science and biomimetics, which is based on the diversity of invertebrate skeletons, particularly the honeycomb structures. In this study, we investigated the unique bioarchitecture principles of the biosilica-based honeycomb-like skeleton of the deep-sea glass sponge Aphrocallistes beatrix. Experimental data provided convincing evidence of the location of actin filaments within the hierarchical siliceous walls of the honeycomb structure. Inspired by the poriferan honeycomb biosilica, we designed various models using 3D printing and microtomography-based 3D reconstruction with PLA, resin, and synthetic glass materials.
Article
Chemistry, Medicinal
Tomas Duminis, Marcin Heljak, Wojciech Swieszkowski, Alexander Ereskovsky, Izabela Dziedzic, Marek Nowicki, Martyna Pajewska-Szmyt, Alona Voronkina, Stefan R. Bornstein, Hermann Ehrlich
Summary: Skeletal constructs of marine sponges, especially those isolated from cultivated demosponges, have the potential to be sustainable sources of biocompatible porous biopolymer-based 3D scaffolds for tissue engineering. These chitinous scaffolds have shown promising results in biomimetics and tissue engineering due to their renewability and broad diversity of cells. However, the mechanical features of these constructs have been poorly studied before.
Article
Chemistry, Medicinal
Anita Kubiak, Martyna Pajewska-Szmyt, Martyna Kotula, Bartosz Lesniewski, Alona Voronkina, Parvaneh Rahimi, Sedigheh Falahi, Korbinian Heimler, Anika Rogoll, Carla Vogt, Alexander Ereskovsky, Paul Simon, Enrico Langer, Armin Springer, Maik Foerste, Alexandros Charitos, Yvonne Joseph, Teofil Jesionowski, Hermann Ehrlich
Summary: This study presents a new biomimetic approach for the development of a lepidocrocite-containing 3D spongin scaffold using artificial seawater and iron. The research proposes a mechanism of lepidocrocite formation and suggests the potential application of the biocomposite as an electrochemical dopamine sensor.
Article
Chemistry, Multidisciplinary
Faezeh Gandomi, Mohammad Javad Taghizadeh, Elnaz Marzi Khosrowshahi, Maryam Saleh Mohammadnia, Neda Irannejad, Esmail Sohouli, Hermann Ehrlich, Yvonne Joseph, Mehdi Rahimi-Nasrabadi
Summary: Azaperone is a phenylbutanone-based neurotransmitter used in veterinary clinics. In this study, a Fe3O4@SiO2-NH2/CS2 nanocomposite was synthesized and used to modify a glassy carbon electrode, creating a sensor for the analysis of Azaperone in ostrich meat and rat plasma. The electrochemical behavior of Azaperone was tested, and the optimal experimental variables, including pH and accumulation time, were determined. The sensor showed a linear response to Azaperone concentration in the range of 0.01-100.0 mu M.
JOURNAL OF NANOSTRUCTURE IN CHEMISTRY
(2023)
