BCP crystals promote chondrocyte hypertrophic differentiation in OA cartilage by sequestering Wnt3a

Targeting β-catenin dependent Wnt signaling via peptidomimetic inhibitors in murine chondrocytes and OA cartilage

(2018) A. Held et al.   OSTEOARTHRITIS AND CARTILAGE

Cushioning the cartilage: a canonical Wnt restricting matter

(2017) Silvia Monteagudo et al.   Nature Reviews Rheumatology

Forced exercise-induced osteoarthritis is attenuated in mice lacking the small leucine-rich proteoglycan decorin

(2016) Tobias Gronau et al.   ANNALS OF THE RHEUMATIC DISEASES

2- and 6-O-sulfated proteoglycans have distinct and complementary roles in cranial axon guidance and motor neuron migration

(2016) Miguel Tillo et al.   DEVELOPMENT

Articular cartilage calcification of the humeral head is highly prevalent and associated with osteoarthritis in the general population

(2016) Thelonius Hawellek et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Articular cartilage calcification of the hip and knee is highly prevalent, independent of age but associated with histological osteoarthritis: evidence for a systemic disorder

(2016) T. Hawellek et al.   OSTEOARTHRITIS AND CARTILAGE

Interleukin-6 and chondrocyte mineralisation act in tandem to promote experimental osteoarthritis

(2015) Sonia Nasi et al.   ANNALS OF THE RHEUMATIC DISEASES

2-O Heparan Sulfate Sulfation by Hs2st Is Required for Erk/Mapk Signalling Activation at the Mid-Gestational Mouse Telencephalic Midline

(2015) Wai Kit Chan et al.   PLoS One

Canonical Wnt signaling skews TGF-β signaling in chondrocytes towards signaling via ALK1 and Smad 1/5/8

(2014) Martijn H. van den Bosch et al.   CELLULAR SIGNALLING

Sulfated Glycosaminoglycans Control the Extracellular Trafficking and the Activity of the Metalloprotease Inhibitor TIMP-3

(2014) Linda Troeberg et al.   CHEMISTRY & BIOLOGY

GDF5 reduces MMP13 expression in human chondrocytes via DKK1 mediated canonical Wnt signaling inhibition

(2014) L. Enochson et al.   OSTEOARTHRITIS AND CARTILAGE

Proteoglycan 4 Expression Protects Against the Development of Osteoarthritis

(2013) M. Z. C. Ruan et al.   Science Translational Medicine

Decreased levels of nucleotide pyrophosphatase phosphodiesterase 1 are associated with cartilage calcification in osteoarthritis and trigger osteoarthritic changes in mice

(2012) J Bertrand et al.   ANNALS OF THE RHEUMATIC DISEASES

Structural Architecture and Functional Evolution of Wnts

(2012) J. Fernando Bazan et al.   DEVELOPMENTAL CELL

Overview of the mechanisms regulating chemokine activity and availability

(2012) Anneleen Mortier et al.   IMMUNOLOGY LETTERS

HSulf-1 inhibits cell proliferation and invasion in human gastric cancer

(2011) Jie Li et al.   CANCER SCIENCE

Exploring Protein Lipidation with Chemical Biology

(2011) Howard C. Hang et al.   CHEMICAL REVIEWS

Growth factor-dependent branching of the ureteric bud is modulated by selective 6-O sulfation of heparan sulfate

(2011) Mita M. Shah et al.   DEVELOPMENTAL BIOLOGY

WNT-3A modulates articular chondrocyte phenotype by activating both canonical and noncanonical pathways

(2011) Giovanna Nalesso et al.   JOURNAL OF CELL BIOLOGY

Inhibitory Peptides of the Sulfotransferase Domain of the Heparan Sulfate Enzyme,N-Deacetylase-N-sulfotransferase-1

(2010) Tarsis F. Gesteira et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transcriptional regulation of endochondral ossification by HIF-2α during skeletal growth and osteoarthritis development

(2010) Taku Saito et al.   NATURE MEDICINE

Leptin receptor JAK2/STAT3 signaling modulates expression of Frizzled receptors in articular chondrocytes

(2010) S. Ohba et al.   OSTEOARTHRITIS AND CARTILAGE

Calcification of articular cartilage in human osteoarthritis

(2009) M. Fuerst et al.   ARTHRITIS AND RHEUMATISM

A study on the interactions between heparan sulfate proteoglycans and Wnt proteins

(2009) Christophe Fuerer et al.   DEVELOPMENTAL DYNAMICS

Specific inhibition of FGF-2 signaling with 2-O-sulfated octasaccharides of heparan sulfate

(2009) S. Ashikari-Hada et al.   GLYCOBIOLOGY

Syndecan-4 regulates ADAMTS-5 activation and cartilage breakdown in osteoarthritis

(2009) Frank Echtermeyer et al.   NATURE MEDICINE

A mouse model of osteochondromagenesis from clonal inactivation of Ext1 in chondrocytes

(2009) K. B. Jones et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cartilage homeostasis in health and rheumatic diseases

(2009) Mary B Goldring et al.   ARTHRITIS RESEARCH & THERAPY

Inhibition of β‐catenin signaling in articular chondrocytes results in articular cartilage destruction

(2008) Mei Zhu et al.   ARTHRITIS AND RHEUMATISM

Identification of the molecular response of articular cartilage to injury, by microarray screening: Wnt-16 expression and signaling after injury and in osteoarthritis

(2008) Francesco Dell'Accio et al.   ARTHRITIS AND RHEUMATISM

Wnt signaling and osteoarthritis

(2008) Frank P. Luyten et al.   BONE

Activation of β-Catenin Signaling in Articular Chondrocytes Leads to Osteoarthritis-Like Phenotype in Adult β-Catenin Conditional Activation Mice

(2008) Mei Zhu et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Wnt/β-catenin signaling stimulates matrix catabolic genes and activity in articular chondrocytes: its possible role in joint degeneration

(2008) Takahito Yuasa et al.   LABORATORY INVESTIGATION

A novel in vivo murine model of cartilage regeneration. Age and strain-dependent outcome after joint surface injury

(2008) N.M. Eltawil et al.   OSTEOARTHRITIS AND CARTILAGE

Expression of novel extracellular sulfatases Sulf-1 and Sulf-2 in normal and osteoarthritic articular cartilage

(2008) Shuhei Otsuki et al.   ARTHRITIS RESEARCH & THERAPY