Forkhead box transcription factor 1: role in the pathogenesis of diabetic cardiomyopathy

Circulating interleukin-1β promotes endoplasmic reticulum stress-induced myocytes apoptosis in diabetic cardiomyopathy via interleukin-1 receptor-associated kinase-2

(2015) Zhongwei Liu et al.   Cardiovascular Diabetology

Rutin administration attenuates myocardial dysfunction in diabetic rats

(2015) Julliano F C Guimaraes et al.   Cardiovascular Diabetology

MuRF2 regulates PPARγ1 activity to protect against diabetic cardiomyopathy and enhance weight gain induced by a high fat diet

(2015) Jun He et al.   Cardiovascular Diabetology

FoxO Transcription Factors and Regenerative Pathways in Diabetes Mellitus

(2015) Kenneth Maiese   CURRENT NEUROVASCULAR RESEARCH

Metformin alleviates hepatosteatosis by restoring SIRT1-mediated autophagy induction via an AMP-activated protein kinase-independent pathway

(2014) Young Mi Song et al.   Autophagy

Fatty Acid-binding Protein 4, a Point of Convergence for Angiogenic and Metabolic Signaling Pathways in Endothelial Cells

(2014) Ulrike Harjes et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Resveratrol-enhanced autophagic flux ameliorates myocardial oxidative stress injury in diabetic mice

(2014) Bo Wang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

QKI deficiency promotes FoxO1 mediated nitrosative stress and endoplasmic reticulum stress contributing to increased vulnerability to ischemic injury in diabetic heart

(2014) Wangang Guo et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Deletion of FoxO1 leads to shortening of QRS by increasing Na+ channel activity through enhanced expression of both cardiac NaV1.5 and β3 subunit

(2014) Benzhi Cai et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Diabetes mellitus activates fetal gene program and intensifies cardiac remodeling and oxidative stress in aged spontaneously hypertensive rats

(2013) Camila Rosa et al.   Cardiovascular Diabetology

FOXO1 impairs whereas statin protects endothelial function in diabetes through reciprocal regulation of Krüppel-like factor 2

(2012) Hae-Young Lee et al.   CARDIOVASCULAR RESEARCH

Calcium Signaling through CaMKII Regulates Hepatic Glucose Production in Fasting and Obesity

(2012) Lale Ozcan et al.   Cell Metabolism

The Role of FOXO and PPAR Transcription Factors in Diet-Mediated Inhibition of PDC Activation and Carbohydrate Oxidation During Exercise in Humans and the Role of Pharmacological Activation of PDC in Overriding These Changes

(2012) Dumitru Constantin-Teodosiu et al.   DIABETES

SERCA2a gene therapy restores microRNA-1 expression in heart failure via an Akt/FoxO3A-dependent pathway

(2012) Regalla Kumarswamy et al.   EUROPEAN HEART JOURNAL

Role of Forkhead Transcription Factors in Diabetes-Induced Oxidative Stress

(2012) Bhaskar Ponugoti et al.   Experimental Diabetes Research

Increased Atherosclerosis and Endothelial Dysfunction in Mice Bearing Constitutively Deacetylated Alleles ofFoxo1Gene

(2012) Li Qiang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Metabolic stress–induced activation of FoxO1 triggers diabetic cardiomyopathy in mice

(2012) Pavan K. Battiprolu et al.   JOURNAL OF CLINICAL INVESTIGATION

FOXO1 Mediates the Autocrine Effect of Endothelin-1 on Endothelial Cell Survival

(2012) Vincenza Cifarelli et al.   MOLECULAR ENDOCRINOLOGY

Role of ER Stress in Ventricular Contractile Dysfunction in Type 2 Diabetes

(2012) Akifumi Takada et al.   PLoS One

Regulation of FoxO transcription factors by acetylation and protein–protein interactions

(2011) Hiroaki Daitoku et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

FoxO transcription factors; Regulation by AKT and 14-3-3 proteins

(2011) Guri Tzivion et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Cardiac triglyceride accumulation following acute lipid excess occurs through activation of a FoxO1–iNOS–CD36 pathway

(2011) Prasanth Puthanveetil et al.   FREE RADICAL BIOLOGY AND MEDICINE

Hydrogen peroxide stress stimulates phosphorylation of FoxO1 in rat aortic endothelial cells

(2010) Ye-yu Wang et al.   ACTA PHARMACOLOGICA SINICA

The FoxO Family in Cardiac Function and Dysfunction

(2010) Sarah M. Ronnebaum et al.   Annual Review of Physiology

The Extending Network of FOXO Transcriptional Target Genes

(2010) Kristan E. van der Vos et al.   ANTIOXIDANTS & REDOX SIGNALING

Forkhead Homeobox Type O Transcription Factors in the Responses to Oxidative Stress

(2010) Peter Storz   ANTIOXIDANTS & REDOX SIGNALING

Role of resveratrol in FOXO1-mediated gluconeogenic gene expression in the liver

(2010) Joo-Man Park et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Structural basis for DNA recognition by FOXO proteins

(2010) Tomas Obsil et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Hyperglycaemia-induced cardiomyocyte death is mediated via MCP-1 production and induction of a novel zinc-finger protein MCPIP

(2010) Craig W. Younce et al.   CARDIOVASCULAR RESEARCH

Deacetylation of FoxO by Sirt1 Plays an Essential Role in Mediating Starvation-Induced Autophagy in Cardiac Myocytes

(2010) Nirmala Hariharan et al.   CIRCULATION RESEARCH

FoxO1 regulates Tlr4 inflammatory pathway signalling in macrophages

(2010) WuQiang Fan et al.   EMBO JOURNAL

The Increase in Cardiac Pyruvate Dehydrogenase Kinase-4 after Short-Term Dexamethasone Is Controlled by an Akt-p38-Forkhead Box Other Factor-1 Signaling Axis

(2010) Prasanth Puthanveetil et al.   ENDOCRINOLOGY

Functional recovery of diabetic mouse hearts by glutaredoxin-1 gene therapy: role of Akt-FoxO-signaling network

(2010) I Lekli et al.   GENE THERAPY

FoxO Transcription Factors Promote Cardiomyocyte Survival upon Induction of Oxidative Stress

(2010) Arunima Sengupta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cytosolic FoxO1: alive and killing

(2010) René H. Medema et al.   NATURE CELL BIOLOGY

Cytosolic FoxO1 is essential for the induction of autophagy and tumour suppressor activity

(2010) Ying Zhao et al.   NATURE CELL BIOLOGY

A Fork in the Path: Developing Therapeutic Inroads with FoxO Proteins

(2010) Kenneth Maiese et al.   Oxidative Medicine and Cellular Longevity

FoxO, Autophagy, and Cardiac Remodeling

(2010) Anwarul Ferdous et al.   Journal of Cardiovascular Translational Research

Diabetic cardiomyopathy – a distinct disease?

(2009) Kaivan Khavandi et al.   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

Regulation of FOXO1-mediated transcription and cell proliferation by PARP-1

(2009) Jun-ichi Sakamaki et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Up-regulation of thioredoxin interacting protein (Txnip) by p38 MAPK and FOXO1 contributes to the impaired thioredoxin activity and increased ROS in glucose-treated endothelial cells

(2009) Xiaonan Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

FOXO1 Plays an Important Role in Enhanced Microvascular Cell Apoptosis and Microvascular Cell Loss in Type 1 and Type 2 Diabetic Rats

(2009) Y. Behl et al.   DIABETES

FoxO1 Haploinsufficiency Protects Against High-Fat Diet-Induced Insulin Resistance With Enhanced Peroxisome Proliferator-Activated Receptor   Activation in Adipose Tissue

(2009) J. J. Kim et al.   DIABETES

Foxo1 Links Hyperglycemia to LDL Oxidation and Endothelial Nitric Oxide Synthase Dysfunction in Vascular Endothelial Cells

(2009) J. Tanaka et al.   DIABETES

FoxO1 Links Insulin Resistance to Proinflammatory Cytokine IL-1  Production in Macrophages

(2009) D. Su et al.   DIABETES

FoxO Transcription Factors Promote Autophagy in Cardiomyocytes

(2009) Arunima Sengupta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Foxo1 integrates insulin signaling with mitochondrial function in the liver

(2009) Zhiyong Cheng et al.   NATURE MEDICINE

The evolution of Fox genes and their role in development and disease

(2009) Sridhar Hannenhalli et al.   NATURE REVIEWS GENETICS

Hypertrophic cardiomyopathy in high-fat diet-induced obesity: role of suppression of forkhead transcription factor and atrophy gene transcription

(2008) Cindy X. Fang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Foxo1 increases pro-inflammatory gene expression by inducing C/EBPβ in TNF-α-treated adipocytes

(2008) Yu Ito et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Oligonucleotide Microarray Analysis of Genes Regulating Apoptosis in Chronically Ischemic and Postinfarction Myocardium

(2008) Józefa Dąbek et al.   BIOCHEMICAL GENETICS

The role of autophagy in the heart

(2008) K Nishida et al.   CELL DEATH AND DIFFERENTIATION

Regulation of Cardiomyocyte Proliferation and Myocardial Growth During Development by FOXO Transcription Factors

(2008) Heather J. Evans-Anderson et al.   CIRCULATION RESEARCH

Inhibition of Foxo1 Protects Pancreatic Islet  -Cells Against Fatty Acid and Endoplasmic Reticulum Stress-Induced Apoptosis

(2008) S. C. Martinez et al.   DIABETES

O-glycosylation of FoxO1 increases its transcriptional activity towards the glucose 6-phosphatase gene

(2008) MeiShiue Kuo et al.   FEBS LETTERS

Arginine Methylation of FOXO Transcription Factors Inhibits Their Phosphorylation by Akt

(2008) Kazuyuki Yamagata et al.   MOLECULAR CELL

The role of FoxO in the regulation of metabolism

(2008) D N Gross et al.   ONCOGENE

Structure/function relationships underlying regulation of FOXO transcription factors

(2008) T Obsil et al.   ONCOGENE

Bcl-2 family proteins and cancer

(2008) K W Yip et al.   ONCOGENE

Generation of Cajal–Retzius neurons in mouse forebrain is regulated by transforming growth factor β-Fox signaling pathways

(2007) Julie A. Siegenthaler et al.   DEVELOPMENTAL BIOLOGY