Article
Chemistry, Analytical
Xinyu Liu, Changchun Zhao, Minyan Zhuang, Xin Meng, Peng Zhang, Guohai Yang
Summary: In this study, a highly sensitive surface-enhanced Raman spectroscopy sensor (SERS) was proposed using 3-methoxyphenylborate pinacol ester (MAPE) modified gold nanoflowers (Au NFs/MAPE) for the detection of ONOO- in living cells. The results show that the SERS sensors have high selectivity and excellent sensitivity for ONOO- in the presence of other interfering ions.
Article
Multidisciplinary Sciences
Yuankai Jin, Wanghuai Xu, Huanhuan Zhang, Ruirui Li, Jing Sun, Siyan Yang, Minjie Liu, Haiyang Mao, Zuankai Wang
Summary: A versatile droplet electrostatic tweezer (DEST) is proposed to remotely and programmatically manipulate droplets, offering potential applications.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2022)
Article
Engineering, Environmental
Yunju Xiao, Weijiang Liu, Ye Zhang, Shuai Zheng, Jianfeng Liao, Huizhuang Shan, Benshun Tian, Tao Wu, Lei Zhang, Zhijie Tu, Yin Hua, Bing Gu, Xuejiao Hu
Summary: In this study, a rapid and sensitive surface-enhanced Raman scattering (SERS)-based biosensor was developed for pathogen detection. The biosensor utilized wheat germ agglutinin (WGA)-modified magnetic nanoparticles as capture elements and co-freezing aptamer/DTNB/AuNps tags as the signal source. The SERS platform showed a high analytical sensitivity, capable of detecting as low as 8 cells/mL of target bacteria. It also successfully detected DNA from difficult-to-culture or slow-growing pathogens. This sensitive and fast SERS platform has great potential for accurate and efficient identification of pathogenic bacteria from various samples.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Chemistry, Analytical
Xiaofeng Liu, Wenhao Zhou, Feiran Tang, Huai Zheng, Sang Woo Joo
Summary: Precise droplet manipulation is crucial for various cutting-edge engineering applications. Existing techniques often lack controllability or suffer from high costs and cross-contamination. A proposed capillary tweezer method, based on curvature-induced immersion force and pillar motion, offers a high-precision and low-cost solution for droplet handling, with potential applications in microfluidics, microfabrication, and bioengineering.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Chemistry, Applied
Ge Wu, Zhengwei Xiong, Suk-Heung Oh, Yanrong Ren, Qiang Wang, Lizhu Yang
Summary: A two-color fluorescent DNA tweezers developed for ultrasensitive detection of OTA shows a good linear range and detection limit, effectively reducing false positive rate in practical food samples.
Article
Biophysics
Lang Li, Zhuyuan Wang, Yang Lu, Kai Zhu, Shenfei Zong, Yiping Cui
Summary: The DaSON strategy utilizes DNA-assisted synthesis of ortho-nanodimer to fabricate Ag (Au) nanodimers with controllable gap width, demonstrating extraordinary reproducibility and enhancement effects in SERS sensing applications.
BIOSENSORS & BIOELECTRONICS
(2021)
Article
Chemistry, Applied
Zhihui Wu, Da-Wen Sun, Hongbin Pu, Qingyi Wei, Xuanran Lin
Summary: A ratiometric surface-enhanced Raman scattering (SERS) aptasensor for AFB1 detection was developed utilizing BPE to trigger the assembly of AuNP dimers and the interaction between MXenes nanosheets and aptamer-modified AuNP dimers. The sensor showed promising results in detecting AFB1 with a limit of detection (LOD) of 0.6 pg.mL(-1) in standard solution.
Article
Chemistry, Analytical
Qi Wang, Fangyuan Zhao, Qingli Yang, Wei Wu
Summary: A fluorescence aptasensor based on DNA walker, DNA tetrahedron nanostructures, and network hybridization chain reaction was proposed for monitoring Aflatoxin B-1 (AFB(1)). The sensor could sensitively detect AFB(1) by utilizing a DNA walker as a signal amplifier and combining DTNs and HCR.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Chemistry, Analytical
Feng Chen, Guodong Li, Chun Wu, Ling Wang, Chung-Nga Ko, Dik-Lung Ma, Chung-Hang Leung
Summary: In this study, a novel method was developed for the ultrasensitive and highly specific detection of miRNA-21. This method exhibited advantages such as lower and constant temperature operation, high specificity, and comparable detection limit with conventional RT-qPCR. The method utilized long-lived probes and rolling circle amplification, and could discriminate between matched and mismatched targets. The application of this method in cancer cells and mouse serum samples showed good agreement with RT-qPCR results.
ANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Analytical
Pan Li, Binbin Zhou, Meihong Ge, Xianghong Jing, Liangbao Yang
Summary: A metal complex-based SERS nanoprobe combined with self-assemble Au NPs active substrates has been developed for sensitive detection of histamine. The nanoprobe demonstrates high sensitivity at 1 mu M level and shows potential in analyzing histamine in complex specimens. The method captures and amplifies Raman signals of histamine, offering a promising approach for histamine detection and monitoring.
Article
Biophysics
Yiqian Kong, Zongyi Li, Lili Zhang, Juncheng Song, Qi Liu, Yinghua Zhu, Na Li, Lili Song, Xiangyang Li
Summary: This study developed a dual mode aptasensor and an intelligent sensor detection platform for rapid and accurate on-site detection of aflatoxin B1 in food. The sensor utilized special nanomaterials and a fluorescent probe to achieve fluorescence/colorimetric detection without the need for material and reagent replacement. The collected signals can be analyzed and modeled on a developed artificial neural network platform, enabling visual intelligent sensing.
BIOSENSORS & BIOELECTRONICS
(2023)
Article
Chemistry, Analytical
Jing Zhou, Dan Yang, Guohui Liu, Siying Li, Wennan Feng, Guocheng Yang, Jin He, Yuping Shan
Summary: A new method has been developed in this study for detecting guanine (G) oxidation products released from live cells using a flexible gold nanoelectrode, allowing high sensitivity and specific response.
Article
Chemistry, Applied
Ximo Wang, Chen Chen, Geoffrey I. N. Waterhouse, Xuguang Qiao, Zhixiang Xu
Summary: A DNA hydrogel surface enhanced Raman spectroscopy sensor was developed for ultrasensitive determination of streptomycin residues in foods. The sensor exhibited specificity and high sensitivity, with good recoveries in milk and honey samples.
Article
Chemistry, Analytical
Eun Ju Kim, Hanbi Kim, Eunkyoung Park, Taekyung Kim, Doo Ryeon Chung, Young-Man Choi, Minhee Kang
Summary: This study introduces a multiplex SERS platform based on a plasmonic paper substrate and double-labeled probe, allowing for highly sensitive detection of multiple fluorescent dyes and the separation and sensitive detection of dyes post-RT-PCR.
ANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Physical
Lingjun Zhang, Jianfeng Sun, Yurui Fang, Yingzhou Huang, Hengyu Guo, Zhong Lin Wang
Summary: This study introduces an ultrasensitive SERS detection system using electrokinetic preconcentration with a triboelectric nanogenerator, which significantly enhances the efficiency of enriching target molecules on the substrate.
Article
Chemistry, Analytical
Yanxin Chu, An-Ping Deng, Wenjing Wang, Jun-Jie Zhu
ANALYTICAL CHEMISTRY
(2019)
Article
Chemistry, Analytical
Wenjing Wang, Axiu Nie, Zhicheng Lu, Jinjie Li, Mingbo Shu, Heyou Han
Article
Chemistry, Analytical
Jiaojiao Zhou, Wenjing Wang, Shuojun Li, Axiu Nie, Zhiyong Song, Mohamed F. Foda, Zhicheng Lu, Ling Zhao, Heyou Han
SENSORS AND ACTUATORS B-CHEMICAL
(2020)
Article
Chemistry, Analytical
Wenjing Wang, Mingbo Shu, Axiu Nie, Heyou Han
SENSORS AND ACTUATORS B-CHEMICAL
(2020)
Article
Chemistry, Analytical
Jiaojiao Zhou, Meishen Ren, Wenjing Wang, Liang Huang, Zhicheng Lu, Zhiyong Song, Mohamed F. Foda, Ling Zhao, Heyou Han
ANALYTICAL CHEMISTRY
(2020)
Review
Biophysics
Jiaojiao Zhou, Yun Li, Wenjing Wang, Xuecai Tan, Zhicheng Lu, Heyou Han
BIOSENSORS & BIOELECTRONICS
(2020)
Article
Chemistry, Multidisciplinary
Shan Huang, Qanying Zhang, Huiqin Yao, Wenjing Wang, Jian-Rong Zhang, Jun-Jie Zhu
Article
Chemistry, Multidisciplinary
Jiaojiao Zhou, Yuqing Li, Wenjing Wang, Zhicheng Lu, Heyou Han, Juewen Liu
Article
Chemistry, Analytical
Jing Ma, Wenjing Wang, Yun Li, Zhicheng Lu, Xuecai Tan, Heyou Han
Summary: A novel PCN-224-based electrochemiluminescence (ECL) system was constructed for sensitive detection of PEDV with the use of TiO2 nanoparticles to amplify the ECL signal. This system achieved a sensitive detection range of 1 pg/mL to 10 ng/mL for PEDV.
ANALYTICAL CHEMISTRY
(2021)
Review
Chemistry, Multidisciplinary
Kai Zhang, Hongyang Li, Wenjing Wang, Jinxuan Cao, Ning Gan, Heyou Han
Article
Chemistry, Analytical
Kaikai Xiang, Gang Chen, AXiu Nie, Wenjing Wang, Heyou Han
Summary: Researchers synthesized silica-based nanoenzymes for rapid detection of Hg2+ concentrations, offering a simple, cost-effective, and fast response method that has been demonstrated to be practical in complex lake water.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Chemistry, Analytical
Wenjing Wang, Yun Li, Axiu Nie, Gao-Chao Fan, Heyou Han
Summary: A lateral flow microRNA-21 biosensing platform was developed using a portable SERS reader and a catalytic hairpin assembly signal amplification strategy, achieving sensitive quantification of microRNA-21 with a detection limit as low as 84 fM. This approach shows great potential for amplified point-of-care biosensing for clinical diagnosis by detecting targets in serum samples.
Article
Chemistry, Multidisciplinary
Qianying Zhang, Wenjing Wang, Shan Huang, Sha Yu, Tingting Tan, Jian-Rong Zhang, Jun-Jie Zhu
Review
Chemistry, Multidisciplinary
Wenjing Wang, Sha Yu, Shan Huang, Sai Bi, Heyou Han, Jian-Rong Zhang, Yi Lu, Jun-Jie Zhu
CHEMICAL SOCIETY REVIEWS
(2019)