Silver(I)‐ and Base‐Mediated formal [4+3] Cycloaddition of in Situ generated 1,2‐Diaza‐1,3‐dienes with C,N ‐Cyclic Azomethine Imines: An Efficient Protocol for the Synthesis of Tetrazepine Derivatives

Rapid Access to Hindered α-Amino Acid Derivatives and Benzodiazepin-3-ones from Aza-Oxyallyl Cations

(2020) YongIl Kwon et al.   ORGANIC LETTERS

Enantioselective Gold(I)-Catalyzed Heterocyclization–Intermolecular Exo [4 + 3]-Cycloaddition Reactions for the Synthesis of Chiral Oxa-Bridged Benzocycloheptanes

(2019) Xiaoyu Di et al.   ORGANIC LETTERS

Rhodium-Catalyzed Regiodivergent [3 + 2] and [5 + 2] Cycloadditions of Quinolinium Ylides with Alkynes

(2019) Min He et al.   ORGANIC LETTERS

Nickel-Catalyzed [5+2] Cycloaddition of 10π-Electron Aromatic Benzothiophenes with Alkynes To Form Thermally Metastable 12π-Electron Nonaromatic Benzothiepines

(2019) Tasuku Inami et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

N-Alkylation-Initiated Redox-Neutral [5 + 2] Annulation of 3-Alkylindoles with o-Aminobenzaldehydes: Access to Indole-1,2-Fused 1,4-Benzodiazepines

(2019) Shuai Wang et al.   ORGANIC LETTERS

Catalytic asymmetric inverse electron demand Diels–Alder reaction of fulvenes with azoalkenes

(2018) Liang Wei et al.   CHEMICAL COMMUNICATIONS

Synthetic Approach to Some New Annulated 1,2,4-Triazine Skeletons with Antimicrobial and Cytotoxic Activities

(2018) Wafaa S. Hamama et al.   JOURNAL OF HETEROCYCLIC CHEMISTRY

Synthesis of 5-(Trifluoromethyl)pyrazolines by Formal [4 + 1]-Annulation of Fluorinated Sulfur Ylides and Azoalkenes

(2018) Zhiyong Wang et al.   ORGANIC LETTERS

Rh(III)-Catalyzed Enaminone-Directed Alkenyl C–H Activation for the Synthesis of Salicylaldehydes

(2018) Bing Qi et al.   ORGANIC LETTERS

Copper-catalyzed radical Heck type cyclization: three-component reaction of DABCO·(SO2)2, aryldiazonium tetrafluoroborates and dienes toward sulfonated benzo- seven-membered nitrogen heterocycles

(2018) Hepan Wang et al.   Organic Chemistry Frontiers

Transition-Metal Free Construction of Isoquinoline-fused Triazines Containing Alkenyl C−X Bonds

(2018) Xiao Cheng et al.   ADVANCED SYNTHESIS & CATALYSIS

Recent Advances in the Chemistry of Conjugated Nitrosoalkenes and Azoalkenes

(2018) Susana M. M. Lopes et al.   CHEMICAL REVIEWS

Divergent Domino Reactions of Sulfur Ylides: Access to Functionalized Six- and Seven-Membered Nitrogen–Heterocycles

(2018) Junlong Chen et al.   ORGANIC LETTERS

Construction of Azepino[2,3-b]indole Core via Sulfur Ylide Mediated Annulations

(2018) Jun-Long Li et al.   ORGANIC LETTERS

Silver(I)- and Base-Mediated [3 + 3]-Cycloaddition of C,N-Cyclic Azomethine Imines with Aza-oxyallyl Cations

(2017) Xiao Cheng et al.   ORGANIC LETTERS

PPh3-Mediated [4 + 2]- and [4 + 1]-Annulations of Maleimides with Azoalkenes: Access to Fused Tetrahydropyridazine/Pyrrolidinedione and Spiro-dihydropyrazole/Pyrrolidinedione Derivatives

(2017) Rong Huang et al.   ORGANIC LETTERS

Construction of 2,3,4,5-tetrahydro-1,2,4-triazines via [4 + 2] cycloaddition of α-halogeno hydrazones to imines

(2017) Hong-Wu Zhao et al.   RSC Advances

Copper(I)-Catalyzed Asymmetric 1,3-Dipolar [3+4] Cycloaddition of Nitrones with Azoalkenes

(2016) Liang Wei et al.   ADVANCED SYNTHESIS & CATALYSIS

Construction of 2,3,4,7-Tetrahydro-1,2,4,5-oxatriazepines via [4+3] Cycloadditions of α-Halogeno Hydrazones with Nitrones

(2016) Hong-Wu Zhao et al.   ADVANCED SYNTHESIS & CATALYSIS

Copper(II)-Catalyzed Asymmetric 1,3-Dipolar [3+4] Cycloaddition and Kinetic Resolution of Azomethine Imines with Azoalkenes

(2016) Liang Wei et al.   ADVANCED SYNTHESIS & CATALYSIS

Asymmetric Synthesis of Spirobenzazepinones with Atroposelectivity and Spiro-1,2-Diazepinones by NHC-Catalyzed [3+4] Annulation Reactions

(2016) Lei Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Reactivity of 1,2-Diaza-1,3-dienes with Azomethine Ylides: [3+4] versus [3+2] Cycloadditions

(2016) Serena Mantenuto et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

[4 + 3] Cycloaddition of Phthalazinium Dicyanomethanides with Azoalkenes Formed in Situ: Synthesis of Triazepine Derivatives

(2016) Wenjun Yang et al.   JOURNAL OF ORGANIC CHEMISTRY

Cu(I)-Catalyzed Asymmetric Multicomponent Cascade Inverse Electron-Demand Aza-Diels–Alder/Nucleophilic Addition/Ring-Opening Reaction Involving 2-Methoxyfurans as Efficient Dienophiles

(2016) Rong Huang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Fluoride-Assisted Synthesis of 1,4,5,6-Tetrahydropyridazines via [4 + 2] Cyclodimerization of in Situ-Generated Azoalkenes Followed by a C–N Bond Cleavage

(2016) Anil M. Shelke et al.   ORGANIC LETTERS

Direct access to non-aromatic 1,2,3,6-tetrahydro-1,2,3,4-tetrazines via [4 + 2] cycloaddition of α-halogeno hydrazones with azodicarboxylic acid derivatives

(2016) Hong-Wu Zhao et al.   RSC Advances

Organocatalyzed Formal [4+2] Cycloaddition ofin situGenerated Azoalkenes with Arylacetic Acids: An Efficient Approach to the Synthesis of 4,5-Dihydropyridazin-3(2H)-ones

(2015) Xuanyi Li et al.   ADVANCED SYNTHESIS & CATALYSIS

Catalytic Enantioselective [5+2] Cycloaddition between Oxidopyrylium Ylides and Enals under Dienamine Activation

(2015) Ane Orue et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

An Unprecedented Formal [5 + 2] Cycloaddition of Nitrones with o-Carboryne via Tandem [3 + 2] Cycloaddition/Oxygen Migration/Aromatization Sequence

(2015) Da Zhao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Asymmetric Cascade Vinylogous Mukaiyama 1,6-Michael/Michael Addition of 2-Silyloxyfurans with Azoalkenes: Direct Approach to Fused Butyrolactones

(2015) Jun Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

1,3-Dipolar cycloadditions of azomethine imines

(2015) Carmen Nájera et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Synthesis of pyrazolo[5,1-a]isoquinolines via a silver(i)-catalyzed reaction of (1-arylethylidene)hydrazides with N′-(2-alkynylbenzylidene)hydrazides

(2015) Xinxing Gong et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

[4 + 2] Cycloaddition of in Situ Generated 1,2-Diaza-1,3-dienes with Simple Olefins: Facile Approaches to Tetrahydropyridazines

(2015) Xingren Zhong et al.   ORGANIC LETTERS

Synthesis of the Tricyclic Ring Structure of Daphnanes via Intramolecular [4 + 3] Cycloaddition/SmI2-Pinacol Coupling

(2015) Ahmed H. E. Hassan et al.   ORGANIC LETTERS

Hexafluoroantimonic Acid Catalysis: Formal [3+2+2] Cycloaddition of Aziridines with Two Alkynes

(2014) Ming-Bo Zhou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Type II Intramolecular [5+2] Cycloaddition: Facile Synthesis of Highly Functionalized Bridged Ring Systems

(2014) Guangjian Mei et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Asymmetric Synthesis of [2,3]-Fused Indoline Heterocycles through Inverse-Electron-Demand Aza-Diels-Alder Reaction of Indoles with Azoalkenes

(2014) Min-Chao Tong et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Amine-Catalyzed Enantioselective 1,3-Dipolar Cycloadditions of Aldehydes to C,N-Cyclic Azomethine Imines

(2014) Wenjun Li et al.   CHEMISTRY-A EUROPEAN JOURNAL

Asymmetric Synthesis of Tetrahydroquinolines through a [3+2] Cycloaddition Controlled by Dienamine Catalysis

(2014) Wenjun Li et al.   CHEMISTRY-A EUROPEAN JOURNAL

A Phosphine-Catalyzed Novel Asymmetric [3+2] Cycloaddition of C,N-Cyclic Azomethine Imines with δ-Substituted Allenoates

(2014) De Wang et al.   CHEMISTRY-A EUROPEAN JOURNAL

Reactivity of Dipyrromethanes towards Azoalkenes: Synthesis of Functionalized Dipyrromethanes, Calix[4]pyrroles, and Bilanes

(2014) Susana M. M. Lopes et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Interceptive [4 + 1] Annulation of in Situ Generated 1,2-Diaza-1,3-dienes with Diazo Esters: Direct Access to Substituted Mono-, Bi-, and Tricyclic 4,5-Dihydropyrazoles

(2014) Orazio A. Attanasi et al.   JOURNAL OF ORGANIC CHEMISTRY

Multicomponent [5 + 2] Cycloaddition Reaction for the Synthesis of 1,4-Diazepines: Isolation and Reactivity of Azomethine Ylides

(2014) Dong Jin Lee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

N-Heterocyclic Carbene Catalyzed Switchable Reactions of Enals with Azoalkenes: Formal [4 + 3] and [4 + 1] Annulations for the Synthesis of 1,2-Diazepines and Pyrazoles

(2014) Chang Guo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of Fused 3-Aminoazepinones via Trapping of a New Class of Cyclic Seven-Membered Allenamides with Furan

(2014) Ben Schurgers et al.   ORGANIC LETTERS

[3 + 3]-Cycloaddition Reactions of α-Acidic Isocyanides with 1,3-Dipolar Azomethine Imines

(2014) Juan Du et al.   ORGANIC LETTERS

Synthesis of naturally occurring tropones and tropolones

(2014) Na Liu et al.   TETRAHEDRON

Silver Triflate-Palladium Chloride Cooperative Catalysis in a Tandem Reaction for the Synthesis ofH-Pyrazolo[5,1-a]isoquinolines

(2013) Qing Xiao et al.   ADVANCED SYNTHESIS & CATALYSIS

Copper-Catalyzed Enantioselective Inverse Electron-Demand Hetero-Diels-Alder Reactions of Diazadienes with Enol Ethers: Efficient Synthesis of Chiral Pyridazines

(2013) Shuang Gao et al.   ADVANCED SYNTHESIS & CATALYSIS

Transfer of Chirality in the Rhodium-Catalyzed Intramolecular [5+2] Cycloaddition of 3-Acyloxy-1,4-enynes (ACEs) and Alkynes: Synthesis of Enantioenriched Bicyclo[5.3.0]decatrienes

(2013) Xing-zhong Shu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of Azepine Derivatives by Silver-Catalyzed [5+2] Cycloaddition ofγ-Amino Ketones with Alkynes

(2013) Ming-Bo Zhou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Effect of ester on rhodium-catalyzed intermolecular [5+2] cycloaddition of 3-acyloxy-1,4-enynes and alkynes

(2013) Casi M. Schienebeck et al.   CHEMICAL COMMUNICATIONS

[4+3] Cycloaddition of in situ generated azoalkenes with C,N-cyclic azomethine imines: efficient synthesis of tetrazepine derivatives

(2013) Xiao-Qiang Hu et al.   CHEMICAL COMMUNICATIONS

Phosphine-catalyzed domino reaction: a novel sequential [2+3] and [3+2] annulation reaction of γ-substituent allenoates to construct bicyclic[3, 3, 0]octene derivatives

(2013) Erqing Li et al.   CHEMICAL COMMUNICATIONS

Synthesis of 3,3′-Spirocyclic Oxindoles via Phosphine Catalyzed [4 + 2] Cyclizations

(2013) Maxime Gicquel et al.   ORGANIC LETTERS

Phosphine-Catalyzed [4 + 2] Annulation of γ-Substituent Allenoates: Facile Access to Functionalized Spirocyclic Skeletons

(2013) Erqing Li et al.   ORGANIC LETTERS

Palladium-catalyzed oxidation of amine in air: an efficient approach to H-pyrazolo[5,1-a]-isoquinolines

(2013) Jie Sheng et al.   TETRAHEDRON

Synthesis of H-pyrazolo[5,1-a]isoquinolines via a silver triflate-catalyzed tandem reaction of N′-(2-alkynylbenzylidene)hydrazide with alcohol

(2013) Wenyan Hao et al.   TETRAHEDRON

A novel and diastereoselective construction of H-pyrazolo[3,2-a]isoquinoline fused spirooxindoles via [3+2] cycloaddition

(2013) Panneerselvam Yuvaraj et al.   TETRAHEDRON LETTERS

Silver triflate–copper(ii) acetate cooperative catalysis in a cascade reaction for concise synthesis of 2-carbonyl H-pyrazolo[5,1-a]isoquinolines

(2012) Zhiyuan Chen et al.   CHEMICAL COMMUNICATIONS

[5 + 2] Cycloaddition Reactions in Organic and Natural Product Synthesis

(2012) Kai E. O. Ylijoki et al.   CHEMICAL REVIEWS

Rhodium-Catalyzed Intra- and Intermolecular [5 + 2] Cycloaddition of 3-Acyloxy-1,4-enyne and Alkyne with Concomitant 1,2-Acyloxy Migration

(2012) Xing-Zhong Shu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Synthesis of Dihydropyrazoles by Formal [4+1] Cycloaddition of in Situ-Derived Azoalkenes and Sulfur Ylides

(2012) Jia-Rong Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of pyrazolo[5,1-a]isoquinolines via silver(i)–rhodium(i) cooperative catalysis in the reaction of N′-(2-alkynylbenzylidene)hydrazide with cycloprop-2-ene-1,1-dicarboxylate

(2012) Liangqing Yao et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

[5 + 1] Cycloaddition of C,N-Cyclic N′-Acyl Azomethine Imines with Isocyanides

(2012) Takahiro Soeta et al.   ORGANIC LETTERS

An efficient approach to H-pyrazolo[5,1-a]isoquinolines via a silver triflate-catalyzed reaction of N′-(2-alkynylbenzylidene)hydrazide with allenoate

(2012) Liang Gao et al.   TETRAHEDRON

A silver(I)–rhodium(I) cooperative catalysis in the reaction of N′-(2-alkynylbenzylidene)hydrazide with 2-vinyloxirane

(2012) Hongliang Liu et al.   TETRAHEDRON

Reaction of N′-(2-alkynylbenzylidene)hydrazide with tertiary amine: a concise synthesis of H-pyrazolo[5,1-a]isoquinolines

(2012) Chao Ye et al.   RSC Advances

An expeditious asymmetric synthesis of the pentacyclic core of the cortistatins by an intramolecular (4+3) cycloaddition

(2011) Lok Lok Liu et al.   CHEMICAL COMMUNICATIONS

Synthesis ofH-Pyrazolo[5,1-a]isoquinolines via Copper(II)-Catalyzed Oxidation of an Aliphatic C−H Bond of Tertiary Amine in Air

(2011) Shaoyu Li et al.   ORGANIC LETTERS

Regioselective formation of medium-ring heterocycles of biological relevance by intramolecular cyclization

(2011) K. C. Majumdar   RSC Advances

Facile Assembly of H-Pyrazolo[5,1-a]isoquinolines via Silver Triflate-Catalyzed One-Pot Tandem Reaction of 2-Alkynyl- benzaldehyde, Sulfonohydrazide, and Ketone or Aldehyde

(2010) Xingxin Yu et al.   ADVANCED SYNTHESIS & CATALYSIS

Silver triflate and N-heterocyclic carbene co-catalyzed reaction of N′-(2-alkynylbenzylidene)hydrazide, methanol with α,β-unsaturated aldehyde

(2010) Zhiyuan Chen et al.   CHEMICAL COMMUNICATIONS

Silver triflate-catalyzed three-component reaction of 2-alkynylbenzaldehyde, sulfonohydrazide, and α,β-unsaturated carbonyl compound

(2010) Shengqing Ye et al.   CHEMICAL COMMUNICATIONS

Exo/endo selectivity-control in Lewis-acid catalyzed tandem heterocyclization/formal [4+3] cycloaddition: synthesis of polyheterocycles from 2-(1-alkynyl)-2-alken-1-ones and 1,3-diphenylisobenzofuran

(2010) Hongyin Gao et al.   CHEMICAL COMMUNICATIONS

Metathesis in the Synthesis of Aromatic Compounds†

(2009) Willem A. L. van Otterlo et al.   CHEMICAL REVIEWS

Cycloadditions of Aromatic Azomethine Imines with 1,1-Cyclopropane Diesters

(2008) Christian Perreault et al.   ORGANIC LETTERS