Benzyne‐Induced Ring Opening Reactions of DABCO: Synthesis of 1,4‐Disubstituted Piperazines and Piperidines

Synthesis and structure-activity relationships for new 6-fluoroquinoline derivatives with antiplasmodial activity

(2019) Patrick Hochegger et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Three-Component Reactions of Arynes, Amines, and Nucleophiles via a One-Pot Process

(2018) Gyoungwook Min et al.   JOURNAL OF ORGANIC CHEMISTRY

Identification of N-Benzyl 3,5-Dinitrobenzamides Derived from PBTZ169 as Antitubercular Agents

(2018) Linhu Li et al.   ACS Medicinal Chemistry Letters

N-Arylation of DABCO with Diaryliodonium Salts: General Synthesis of N-Aryl-DABCO Salts as Precursors for 1,4-Disubstituted Piperazines

(2018) Dmitry I. Bugaenko et al.   ORGANIC LETTERS

Design, synthesis and antimycobacterial activity of novel imidazo[1,2- a ]pyridine-3-carboxamide derivatives

(2017) Kai Lv et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthetic Approaches to the New Drugs Approved During 2015

(2017) Andrew C. Flick et al.   JOURNAL OF MEDICINAL CHEMISTRY

Quaternary N-(2-Pyridyl)-DABCO Salts: One-Pot in Situ Formation from Pyridine-N-oxides and Reactions with Nucleophiles: A Mild and Selective Route to Substituted N-(2-Pyridyl)-N′-ethylpiperazines

(2017) Dmitry I. Bugaenko et al.   JOURNAL OF ORGANIC CHEMISTRY

Reactions of hexadehydro-Diels–Alder benzynes with structurally complex multifunctional natural products

(2017) Sean P. Ross et al.   Nature Chemistry

Multiheterocyclic Motifs via Three-Component Reactions of Benzynes, Cyclic Amines, and Protic Nucleophiles

(2017) Sean P. Ross et al.   ORGANIC LETTERS

Design, synthesis, and biological evaluation of arylpiperazine–benzylpiperidines with dual serotonin and norepinephrine reuptake inhibitory activities

(2016) Suresh Paudel et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Design, Synthesis, and Biological Evaluation of Novel 2-((2-(4-(Substituted)phenylpiperazin-1-yl)ethyl)amino)-5′-N-ethylcarboxamidoadenosines as Potent and Selective Agonists of the A2A Adenosine Receptor

(2015) Delia Preti et al.   JOURNAL OF MEDICINAL CHEMISTRY

The Reaction of DABCO with 4-Chloro-5H-1,2,3-dithiazoles: Synthesis and Chemistry of 4-[N-(2-Chloroethyl)piperazin-1-yl]-5H-1,2,3-dithiazoles

(2015) Maria Koyioni et al.   JOURNAL OF ORGANIC CHEMISTRY

Binding Kinetics of ZM241385 Derivatives at the Human Adenosine A2AReceptor

(2014) Dong Guo et al.   ChemMedChem

Enhancing a CH−π Interaction to Increase the Affinity for 5-HT1A Receptors

(2014) Jean-François Liégeois et al.   ACS Medicinal Chemistry Letters

Versatile Synthesis of Disubstituted Triazole Library for Dopamine and Serotonin Receptor Ligands

(2011) Kamalkishor P. Landge et al.   BULLETIN OF THE KOREAN CHEMICAL SOCIETY

Chemical Modifications on 4-Arylpiperazine-Ethyl Carboxamide Derivatives Differentially Modulate Affinity for 5-HT1A, D4.2, and α2AReceptors: Synthesis and In Vitro Radioligand Binding Studies

(2010) Amaury Graulich et al.   AUSTRALIAN JOURNAL OF CHEMISTRY

Benzimidazolone-based serotonin 5-HT1A or 5-HT7R ligands: Synthesis and biological evaluation

(2009) Eduard Badarau et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

EfficientN-Arylation/Dealkylation of Electron Deficient Heteroaryl Chlorides and Bicyclic Tertiary Amines under Microwave Irradiation

(2009) Hong-Jun Wang et al.   JOURNAL OF COMBINATORIAL CHEMISTRY

Efficient microwave-assisted three-component one-pot preparation of 1-aryl-4-(2-acetoxyethyl)piperazines and 1-aryl-4-(2-acetoxyethyl)piperidines

(2009) S. Gabrielle Gladstone et al.   TETRAHEDRON LETTERS