RIP1 promotes proliferation through G2/M checkpoint progression and mediates cisplatin-induced apoptosis and necroptosis in human ovarian cancer cells

Targeting RIPK1 for the treatment of human diseases

(2019) Alexei Degterev et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RIP1 protects melanoma cells from apoptosis induced by BRAF/MEK inhibitors

(2018) Fu Xi Lei et al.   Cell Death & Disease

RIP Kinases in Liver Cell Death, Inflammation and Cancer

(2018) Vangelis Kondylis et al.   TRENDS IN MOLECULAR MEDICINE

Ovarian cancer

(2017) Carlo La Vecchia   EUROPEAN JOURNAL OF CANCER PREVENTION

RIP1-dependent reactive oxygen species production executes artesunate-induced cell death in renal carcinoma Caki cells

(2017) Anil Kumar Chauhan et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Histone H4 expression is cooperatively maintained by IKKβ and Akt1 which attenuates cisplatin-induced apoptosis through the DNA-PK/RIP1/IAPs signaling cascade

(2017) Ruixue Wang et al.   Scientific Reports

Biomarkers for the detection of necroptosis

(2016) Sudan He et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

RIP1 Kinase Is an Oncogenic Driver in Melanoma

(2015) X. Y. Liu et al.   CANCER RESEARCH

RIP1 maintains DNA integrity and cell proliferation by regulating PGC-1α-mediated mitochondrial oxidative phosphorylation and glycolysis

(2014) W Chen et al.   CELL DEATH AND DIFFERENTIATION

Receptor-interacting Protein 1 Increases Chemoresistance by Maintaining Inhibitor of Apoptosis Protein Levels and Reducing Reactive Oxygen Species through a microRNA-146a-mediated Catalase Pathway

(2014) Qiong Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Necroptosis in health and diseases

(2014) Wen Zhou et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

RIP1 potentiates BPDE-induced transformation in human bronchial epithelial cells through catalase-mediated suppression of excessive reactive oxygen species

(2013) Qiong Wang et al.   CARCINOGENESIS

A JNK-mediated autophagy pathway that triggers c-IAP degradation and necroptosis for anticancer chemotherapy

(2013) W He et al.   ONCOGENE

ARD1 binding to RIP1 mediates doxorubicin-induced NF-κB activation

(2012) Jonggyu Park et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

IAPs: Guardians of RIPK1

(2011) M Darding et al.   CELL DEATH AND DIFFERENTIATION

Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012

(2011) L Galluzzi et al.   CELL DEATH AND DIFFERENTIATION

Multiple death pathways in TNF-treated fibroblasts: RIP3- and RIP1-dependent and independent routes

(2011) Duan-Wu Zhang et al.   CELL RESEARCH

RIP1 comes back to life as a cell death regulator in TNFR1 signaling

(2011) Marie Anne O’Donnell et al.   FEBS Journal

The Ripoptosome, a Signaling Platform that Assembles in Response to Genotoxic Stress and Loss of IAPs

(2011) Tencho Tenev et al.   MOLECULAR CELL

The Ripoptosome: Death Decision in the Cytosol

(2011) Mathieu J.M. Bertrand et al.   MOLECULAR CELL

Blocking NF-κB and Akt by Hsp90 inhibition sensitizes Smac mimetic compound 3-induced extrinsic apoptosis pathway and results in synergistic cancer cell death

(2010) Lang Bai et al.   APOPTOSIS

Down-regulation of RIP expression by 17-dimethylaminoethylamino-17-demethoxygeldanamycin promotes TRAIL-induced apoptosis in breast tumor cells

(2009) Carmen Palacios et al.   CANCER LETTERS

The Receptor Interacting Protein 1 Inhibits p53 Induction through NF- B Activation and Confers a Worse Prognosis in Glioblastoma

(2009) S. Park et al.   CANCER RESEARCH

Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes

(2009) L Galluzzi et al.   CELL DEATH AND DIFFERENTIATION

TNF-α Induces Two Distinct Caspase-8 Activation Pathways

(2008) Lai Wang et al.   CELL

Identification of a Molecular Signaling Network that Regulates a Cellular Necrotic Cell Death Pathway

(2008) Junichi Hitomi et al.   CELL