Ultrasensitive RT-QuIC assay with high sensitivity and specificity for Lewy body-associated synucleinopathies

Discriminating α-synuclein strains in Parkinson’s disease and multiple system atrophy

(2020) Mohammad Shahnawaz et al.   NATURE

Detection of prions in skin punch biopsies of Creutzfeldt–Jakob disease patients

(2020) Angela Mammana et al.   Annals of Clinical and Translational Neurology

Risk and predictors of dementia and parkinsonism in idiopathic REM sleep behaviour disorder: a multicentre study

(2019) Ronald B Postuma et al.   BRAIN

Seeding Variability of Different Alpha Synuclein Strains in Synucleinopathies

(2019) Niccolò Candelise et al.   ANNALS OF NEUROLOGY

α‐Synuclein real‐time quaking‐induced conversion in the cerebrospinal fluid of uncertain cases of parkinsonism

(2019) Anouke van Rumund et al.   ANNALS OF NEUROLOGY

CSF and blood biomarkers for Parkinson's disease

(2019) Lucilla Parnetti et al.   LANCET NEUROLOGY

4-Repeat tau seeds and templating subtypes as brain and CSF biomarkers of frontotemporal lobar degeneration

(2019) Eri Saijo et al.   ACTA NEUROPATHOLOGICA

Pure Autonomic Failure

(2019) Elizabeth A. Coon et al.   MAYO CLINIC PROCEEDINGS

Multiple System Atrophy: Recent Developments and Future Perspectives

(2019) Wassilios G. Meissner et al.   MOVEMENT DISORDERS

α‐Synuclein RT‐QuIC assay in cerebrospinal fluid of patients with dementia with Lewy bodies

(2019) Matilde Bongianni et al.   Annals of Clinical and Translational Neurology

α-Synuclein strains target distinct brain regions and cell types

(2019) Angus Lau et al.   NATURE NEUROSCIENCE

Rapid and ultra-sensitive quantitation of disease-associated α-synuclein seeds in brain and cerebrospinal fluid by αSyn RT-QuIC

(2018) Bradley R. Groveman et al.   Acta Neuropathologica Communications

The natural history of idiopathic autonomic failure

(2018) Giulia Giannini et al.   NEUROLOGY

Parkinson's disease and multiple system atrophy have distinct α-synuclein seed characteristics

(2018) Tritia R. Yamasaki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Prion-related peripheral neuropathy in sporadic Creutzfeldt-Jakob disease

(2018) Simone Baiardi et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Clinical diagnosis of progressive supranuclear palsy: The movement disorder society criteria

(2017) Günter U. Höglinger et al.   MOVEMENT DISORDERS

α-synuclein toxicity in neurodegeneration: mechanism and therapeutic strategies

(2017) Yvette C Wong et al.   NATURE MEDICINE

Idiopathic REM sleep behaviour disorder and neurodegeneration — an update

(2017) Birgit Högl et al.   Nature Reviews Neurology

Non-motor features of Parkinson disease

(2017) Anthony H. V. Schapira et al.   NATURE REVIEWS NEUROSCIENCE

Diagnosis and management of dementia with Lewy bodies

(2017) Ian G. McKeith et al.   NEUROLOGY

High diagnostic value of second generation CSF RT-QuIC across the wide spectrum of CJD prions

(2017) Alessia Franceschini et al.   Scientific Reports

Development of a Biochemical Diagnosis of Parkinson Disease by Detection of α-Synuclein Misfolded Aggregates in Cerebrospinal Fluid

(2017) Mohammad Shahnawaz et al.   JAMA Neurology

Like prions: the propagation of aggregated tau and α-synuclein in neurodegeneration

(2016) Michel Goedert et al.   BRAIN

Idiopathic rapid eye movement sleep behaviour disorder: diagnosis, management, and the need for neuroprotective interventions

(2016) Alex Iranzo et al.   LANCET NEUROLOGY

Advanced tests for early and accurate diagnosis of Creutzfeldt–Jakob disease

(2016) Gianluigi Zanusso et al.   Nature Reviews Neurology

Review: The spectrum of clinical features seen with alpha synuclein pathology

(2016) R. A. Barker et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Alpha-synuclein RT-QuIC in the CSF of patients with alpha-synucleinopathies

(2016) Graham Fairfoul et al.   Annals of Clinical and Translational Neurology

Neurodegenerative Diseases: Expanding the Prion Concept

(2015) Lary C. Walker et al.   Annual Review of Neuroscience

Parkinson's disease

(2015) Lorraine V Kalia et al.   LANCET

Stability and Reproducibility Underscore Utility of RT-QuIC for Diagnosis of Creutzfeldt-Jakob Disease

(2015) Maria Cramm et al.   MOLECULAR NEUROBIOLOGY

MDS clinical diagnostic criteria for Parkinson's disease

(2015) Ronald B. Postuma et al.   MOVEMENT DISORDERS

α-Synuclein strains cause distinct synucleinopathies after local and systemic administration

(2015) W. Peelaerts et al.   NATURE

Evidence for α-synuclein prions causing multiple system atrophy in humans with parkinsonism

(2015) Stanley B. Prusiner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rapid and Sensitive RT-QuIC Detection of Human Creutzfeldt-Jakob Disease Using Cerebrospinal Fluid

(2015) Christina D. Orrú et al.   mBio

Bank Vole Prion Protein As an Apparently Universal Substrate for RT-QuIC-Based Detection and Discrimination of Prion Strains

(2015) Christina D. Orrú et al.   PLoS Pathogens

Primary age-related tauopathy (PART): a common pathology associated with human aging

(2014) John F. Crary et al.   ACTA NEUROPATHOLOGICA

International Classification of Sleep Disorders-Third Edition

(2014) Michael J Sateia   CHEST

Advancing research diagnostic criteria for Alzheimer's disease: the IWG-2 criteria

(2014) Bruno Dubois et al.   LANCET NEUROLOGY

Neurodegenerative Disorder Risk in Idiopathic REM Sleep Behavior Disorder: Study in 174 Patients

(2014) Alex Iranzo et al.   PLoS One

Criteria for the diagnosis of corticobasal degeneration

(2013) M. J. Armstrong et al.   NEUROLOGY

Structural and functional characterization of two alpha-synuclein strains

(2013) Luc Bousset et al.   Nature Communications

Consensus classification of human prion disease histotypes allows reliable identification of molecular subtypes: an inter-rater study among surveillance centres in Europe and USA

(2012) Piero Parchi et al.   ACTA NEUROPATHOLOGICA

Real time quaking-induced conversion analysis of cerebrospinal fluid in sporadic Creutzfeldt-Jakob disease

(2012) Lynne I. McGuire et al.   ANNALS OF NEUROLOGY

Neuropathology underlying clinical variability in patients with synucleinopathies

(2011) Glenda M. Halliday et al.   ACTA NEUROPATHOLOGICA

National Institute on Aging–Alzheimer’s Association guidelines for the neuropathologic assessment of Alzheimer’s disease: a practical approach

(2011) Thomas J. Montine et al.   ACTA NEUROPATHOLOGICA

Ultrasensitive human prion detection in cerebrospinal fluid by real-time quaking-induced conversion

(2011) Ryuichiro Atarashi et al.   NATURE MEDICINE

Incidence and spectrum of sporadic Creutzfeldt–Jakob disease variants with mixed phenotype and co-occurrence of PrPSc types: an updated classification

(2009) Piero Parchi et al.   ACTA NEUROPATHOLOGICA

Staging/typing of Lewy body related α-synuclein pathology: a study of the BrainNet Europe Consortium

(2009) Irina Alafuzoff et al.   ACTA NEUROPATHOLOGICA

Second consensus statement on the diagnosis of multiple system atrophy

(2008) S. Gilman et al.   NEUROLOGY