Article
Immunology
Hung N. Mai, Luis Fernando Aranguren Caro, Roberto Cruz-Flores, Brenda Noble White, Arun K. Dhar
Summary: A selected genetic line of Penaeus vannamei was found to be tolerant to Acute Hepatopancreatic Necrosis Disease (AHPND), and differential gene expression analysis between susceptible and tolerant shrimp populations revealed potential candidate markers for AHPND tolerance.
FRONTIERS IN IMMUNOLOGY
(2021)
Article
Fisheries
Kelly Condon, Roger Huerlimann, Tony Charles, Ryan Lowrey, Phoebe Arbon, Dean R. Jerry
Summary: Vibrio-related diseases have significant economic impact on global shrimp production. This study investigated a mass mortality event at a commercial tiger prawn hatchery, revealing Vibrio-related sequences and putative virulence genes. Whole genome sequencing and qPCR analysis showed the impact of different antibiotics on the expression of toxin genes in shrimp postlarvae.
Article
Fisheries
Md. Shahdat Hossain, Jingcheng Dai, Dongru Qiu
Summary: AHPND, caused by Vibrio parahaemolyticus, is a severe hepatopancreatic disease of shrimp, linked to gut bacterial imbalance and selective pressure on microbiota. The presence of pirA(Vp) toxin alone is sufficient to alter the core microbiota of infected shrimp. Infected shrimp show enrichment in Firmicutes and Bacteroidetes, while Proteobacteria levels decrease. Significant differences in SCFAs-producing species were found between healthy and infected shrimp gut.
AQUACULTURE RESEARCH
(2021)
Article
Fisheries
Md. Lifat Rahi, Wasim Sabbir, Krishna R. Salin, Dania Aziz, David A. Hurwood
Summary: The study showed that the pathogens VP and WSSV significantly reduced hemocyte counts and increased glucose and serotonin levels in the hemolymph of black tiger shrimp. These pathogenic treatments altered the expression pattern of candidate genes and affected the physiological and biochemical parameters, resulting in negative impacts on growth and mortality of the experimental shrimps.
Article
Environmental Sciences
Xieyan Chen, Zihao He, Jichen Zhao, Minze Liao, Yuan Xue, Jianing Zhou, Rowena Hoare, Sean J. Monaghan, Na Wang, Huanying Pang, Chengbo Sun
Summary: Biofloc technology (BFT) is a promising aquaculture technology for improving water quality, waste treatment, and disease prevention. This study used high-throughput sequencing to compare bacteria in mariculture ponds and found Proteobacteria to be the dominant group. Functional annotation revealed a predominance of metabolism genes and high abundance of antibiotic resistance genes.
FRONTIERS IN MARINE SCIENCE
(2022)
Article
Fisheries
Hongdi Fan, Yundong Li, Qibin Yang, Song Jiang, Lishi Yang, Jianhua Huang, Shigui Jiang, Falin Zhou
Summary: The study cloned a MAPKK cDNA from black tiger shrimp and found that it plays a crucial role in stress resistance and immunity. The expression of PmMAPKK was highest in the ovary and varied in different tissues and developmental stages. In bacterial infection and low-salinity stress experiments, PmMAPKK expression levels were significantly altered, affecting the mortality rate of shrimp under stress conditions. The activation of ERK, JNK, and p38 signaling pathways suggested complex regulatory mechanisms in the MAPK signaling pathway. These results indicate the involvement of PmMAPKK in the innate immune mechanism of P. monodon and its adaptation to low-salinity environments.
AQUACULTURE REPORTS
(2021)
Article
Fisheries
Chao Zhao, Chao Peng, Pengfei Wang, Bo Zhang, Lulu Yan, Chun-Lin Wang, Lihua Qiu
Summary: In this study, a novel TRIM37 homolog called PmTRIM37 was identified, which plays important roles in regulating innate immune processes, particularly antiviral and proinflammatory cytokine responses. PmTRIM37 is highly expressed in immune-related tissues and its expression is up-regulated after white spot syndrome virus (WSSV) infection. Knockdown of PmTRIM37 promotes WSSV replication and VP28 expression, suggesting its negative role in WSSV infection. Furthermore, PmTRIM37 positively regulates the NF-κB pathway and Antimicrobial peptides (AMP) expression during WSSV infection.
FISH & SHELLFISH IMMUNOLOGY
(2023)
Article
Fisheries
Rui Fan, Yundong Li, Shigui Jiang, Song Jiang, Qibin Yang, Lishi Yang, Jianhua Huang, Falin Zhou
Summary: This study cloned the Grx3 of Penaeus monodon (PmGrx3) and revealed its basic information and distribution in the organism, as well as its expression patterns. The results suggest that PmGrx3 may play an important role in shrimp's resistance against environmental stress and pathogen infection.
AQUACULTURE INTERNATIONAL
(2021)
Article
Fisheries
Pakpoom Boonchuen, Hafeeza Sakhor, Phattarunda Jaree, Kunlaya Somboonwiwat
Summary: Acute hepatopancreatic necrosis disease (AHPND) caused by a specific strain of Vibrio parahaemolyticus results in significant global shrimp production loss. A study identified differentially expressed immune-related genes in white shrimp hemocytes upon VPAHPND infection, with Vago5 being an early infection-responsive gene that plays a role in modulating antibacterial infection through activation of NF-kappa B mediated pathways, JAK/STAT pathway, and phenoloxidase system.
FISH & SHELLFISH IMMUNOLOGY
(2022)
Article
Fisheries
Jian-An Xian, Pei-Hua Zheng, Yao-Peng Lu, Jun-Tao Li, Ze-Long Zhang, Xiu-Xia Zhang, Dong-Mei Wang, Lei Wang
Summary: Flow cytometric analysis revealed three types of haemocytes in Penaeus monodon, showing variations in morphologic and immunological characteristics. Granular cells and semigranular cells are actively involved in cellular defence, with the former having the highest immune activities and the latter being the most abundant in circulation.
AQUACULTURE REPORTS
(2021)
Article
Fisheries
Md Lifat Rahi, Shujon Mahmud, Khurshid Jahan Dilruba, Wasim Sabbir, Dania Aziz, David A. Hurwood
Summary: The study found that higher temperatures can significantly increase the expression of female sex determining genes in black tiger shrimp larvae, resulting in a larger proportion of females. Conversely, lower temperatures lead to a higher proportion of males. Additionally, temperature has a significant impact on the growth performance of shrimp individuals.
AQUACULTURE REPORTS
(2021)
Article
Engineering, Marine
Yundong Li, Falin Zhou, Hongdi Fan, Song Jiang, Qibin Yang, Jianhua Huang, Lishi Yang, Xu Chen, Wenwen Zhang, Shigui Jiang
Summary: MKK4 is a key component of the JNK signaling pathway and plays a crucial role in immunity and stress adaptation. The gene expression of PmMKK4 varies in response to bacterial infections and low-salinity stress, indicating its importance in innate immunity and environmental adaptation.
JOURNAL OF MARINE SCIENCE AND ENGINEERING
(2022)
Article
Fisheries
Prawit Oangkhana, Piti Amparyup, Anchalee Tassanakajon, Elumalai Preetham, Ratree Wongpanya
Summary: In this study, a fibrinogen-related protein in the black tiger shrimp Penaeus monodon was identified and characterized. The PmFreP was found to be mainly expressed in the intestine, able to bind bacteria and facilitate the clearance of pathogens in shrimp innate immunity. These results suggest that PmFreP may serve as pattern recognition receptors implicated in shrimp innate immunity.
FISH & SHELLFISH IMMUNOLOGY
(2021)
Article
Fisheries
Wan Omar Haifa-Haryani, Mohamad Azzam-Sayuti, Md. Ali Amatul-Samahah, Yong Kit Chin, Mohd Zamri-Saad, Salleh Annas, I. Natrah, Mohammad Noor Azmai Amal, Md Yasin Ina-Salwany
Summary: This study investigated the distribution of Vibrio spp. in cultured shrimp in different regions of Peninsular Malaysia. Out of the 225 isolates examined, 13 Vibrio spp. were identified and characterized. The virulence genes and pathogenicity of V. parahaemolyticus S12-3 towards P. monodon were demonstrated, highlighting the importance of microbiological risk assessments for shrimp farming.
AQUACULTURE RESEARCH
(2023)
Article
Immunology
Suthinee Soponpong, Piti Amparyup, Taro Kawai, Anchalee Tassanakajon
Summary: The study reveals the importance of PmIRF in the antiviral immunity of black tiger shrimp. PmIRF regulates the production of interferon-like molecules and antimicrobial peptides through the PmDDX41-PmSTING DNA sensing pathway.
FRONTIERS IN IMMUNOLOGY
(2022)
Review
Fisheries
Li Lian Wong, Siti Aisyah Razali, Zulaikha Mat Deris, Muhd Danish-Daniel, Min Pau Tan, Siti Azizah Mohd Nor, Hongyu Ma, Wang Min, Liang Yantao, Md Asaduzzaman, Yeong Yik Sung, Zhanjiang Liu, Patrick Sorgeloos, Yves Van de Peer, Nor Afiqah-Aleng
Summary: High-throughput sequencing technologies have been widely applied in aquaculture research, providing important data support for disease management, breeding programs, etc.
Article
Oceanography
Meiaoxue Han, Shunan Cao, Guangfu Luo, Jianfeng He, Yantao Liang, Xuechao Chen, Chengxiang Gu, Gang Liu, Ziyue Wang, Wenjing Zhang, Yue Dong, Jun Zhao, Qiang Hao, Hongbing Shao, Yeong Yik Sung, Wen Jye Mok, Li Lian Wong, Andrew McMinn, Min Wang
Summary: The summer distribution of virio- and picoplankton in the Indian Ocean sector of East Antarctica is mainly controlled by ice melting and upwelling of the Circumpolar Deep Water (CDW). Different areas show variations in marine biological composition and abundance, with viruses exhibiting correlations with different types of plankton.
DEEP-SEA RESEARCH PART II-TOPICAL STUDIES IN OCEANOGRAPHY
(2022)
Article
Biodiversity Conservation
Min Pau Tan, Revarunan Sammogam, Nuralif Fakhrullah Mohd Nur, Nur Ilham Syahadah Mohd Yusoff, Tun Nurul Aimi Mat Jaafar, Siti Azizah Mohd Nor, Yeong Yik Sung, Muhd Danish-Daniel, Sekar Megarajan
Summary: This study investigated the genetic variability, structure, and phylogenetic relationships of the brushtooth lizardfish from the east coast of Peninsular Malaysia. The results showed moderate haplotype diversity and low nucleotide diversity in this population, suggesting a recent population expansion. The study also found higher nucleotide polymorphism in near shore and shallower waters, indicating better habitat quality and/or less fishing pressure. Genetic homogeneity within the study area and genetic similarity to populations in the Mediterranean coast of Turkey were observed. These findings highlight the importance of protecting habitat areas and implementing a single-stock management regime for the conservation of this economically important fishery resource.
MARINE BIODIVERSITY
(2022)
Article
Fisheries
Liqing, Mat Taib Mimi Iryani, Aijun Lv, Jinfeng Sun, Anupa Anirudhan, Min Pau Tan, Muhd Danish-Daniel, Li Lian Wong, Kartik Baruah, Patrick Sorgeloos, Tengku Sifzizul Tengku Muhammad, Min Wang, Yantao Liang, Wen Jye Mok, Yeong Yik Sung
Summary: Temperature, pH, salinity, and ammonia stress have adverse effects on the performance and well-being of aquatic organisms, especially those used in aquaculture. The induction of Hsp70 in these organisms improves their tolerance to subsequent abiotic stress. This study demonstrates the functional role of Hsp70 in stress tolerance using RNAi technology.
Article
Biology
Mohamad N. Azra, Mohd Iqbal Mohd Noor, Yeong Yik Sung, Mahmoud A. O. Dawood, Mazlan Abd Ghaffar
Summary: This study aimed to understand the current state, development trends, and research hotspots of thermal tolerance by conducting a scientometric analysis of relevant literature. The results revealed significant increases in the size of the literature, citation frequency, and investigated hotspots in the field of thermal tolerance. The thematic clusters of oxygen consumption, heat shock protein, climate change, and temperature were identified as the most common areas of research.
JOURNAL OF THERMAL BIOLOGY
(2022)
Article
Chemistry, Multidisciplinary
Sana Wahid, Sajid Jahangir, Muhammad Ali Versiani, Khalid Mohammed Khan, Yeong Yik Sung, Jamshed Iqbal, Abdul Wadood, Kanwal, Ashfaq Ur Rehman, Arshia, Muhammad Uzair, Imtiaz Ali Khan, Muhammad Taha, Shahnaz Perveen
Summary: In this study, twenty structural variants of nitrofurazone were synthesized using a biology-oriented drug synthesis approach. The synthesized molecules were characterized using spectroscopic techniques, and their alpha-glucosidase inhibitory activity was determined. Several compounds showed potent inhibition against alpha-glucosidase, with compound 19 being the most active. Molecular docking and dynamic simulation were used to study the binding interactions and stability of the active compounds.
ARABIAN JOURNAL OF CHEMISTRY
(2022)
Review
Agriculture, Dairy & Animal Science
Mohamad Nor Azra, Mohd Iqbal Mohd Noor, Juris Burlakovs, Muhammad Fuad Abdullah, Zulkiflee Abd Latif, Yeong Yik Sung
Summary: This study aimed to identify the current trends, research gaps, and literature development in the study of Artemia around the world. Using scientometric analyses, the study revealed that significant contributions in Artemia research primarily originated from the USA, Brazil, Spain, India, China, and Belgium. The study also identified the top keywords and emerging trends related to Artemia research, as well as generated co-citation clusters.
Article
Environmental Sciences
Zulaikha Mat Deris, Shumpei Iehata, Han Ming Gan, Mhd Ikhwanuddin, Musa Najiah, Md Asaduzzaman, Min Wang, Yantao Liang, Muhd Danish-Daniel, Yeong Yik Sung, Li Lian Wong
Summary: This study explores the effects of salinity levels and pathogenic Vibrio harveyi infection on the gut microbiota of Litopenaeus vannamei shrimp. The results show that shrimp cultured at a salinity of 20 ppt exhibit higher microbiota diversity, a stable bacterial network, and the presence of beneficial bacteria that help inhibit the growth of pathogens. The study concludes that a salinity of 20 ppt is optimal for suppressing the growth of V. harveyi and potential pathogenic bacteria in the shrimp gut.
FRONTIERS IN MARINE SCIENCE
(2022)
Article
Biochemistry & Molecular Biology
Ying-Chao Ma, Mei-Rong Gao, Huan Yang, Jun-Yao Jiang, Wei Xie, Wan-Ping Su, Bo Zhang, Yik-Sung Yeong, Wu-Yan Guo, Li-Ying Sui
Summary: This study aims to find more cost-effective and manageable ways of producing C-50 carotenoids. The results showed that using natural brine medium and adding glucose, sucrose, and lactose can enhance both biomass and carotenoid productivity. The best conditions for open fermentation were salinity 20-25%, rotation speed 150-200 rpm, and pH 7.0-8.2. The open fermentation of Halorubrum is a promising method for producing C-50 carotenoids.
APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY
(2023)
Article
Ecology
Siti Zuraida Zulkipli, Chee Ping Tan, Ying Giat Seah, Hon Jung Liew, Yeong Yik Sung, Masashi Ando, Min Wang, Yantao Liang, Andrew McMinn, Wen Jye Mok
Summary: This study investigated mercury contamination in common commercial marine fish from the South China Sea. The muscle tissue mercury levels of four species were analyzed, and their trophic level was assessed. The results revealed variations in mercury concentrations among species, with Epinephelus heniochus having the highest concentration and Scomberomorus guttatus having the lowest. Factors such as size, food composition, and habitat were identified as the major influences on mercury levels in these fishes.
REGIONAL STUDIES IN MARINE SCIENCE
(2023)
Article
Environmental Sciences
Linyi Ren, Yundan Liu, Yantao Liang, Baohong Liu, Andrew McMinn, Kaiyang Zheng, Ziyue Wang, Hongmin Wang, Hongbing Shao, Yeong Yik Sung, Wen Jye Mok, Li Lian Wong, Min Wang
Summary: A new Pseudomonas phage, vB_PsaP_M1, has been discovered, which has a distant evolutionary relationship with previously isolated viruses and belongs to a new viral cluster called Psaeviridae. Additionally, two unique genes were found in this phage, confirming the proposal for a new viral family.
FRONTIERS IN MARINE SCIENCE
(2022)
Article
Environmental Sciences
Yajun Jing, Ruizhe Guo, Hongmin Wang, Yantao Liang, Yundan Liu, Yifei Feng, Qin Ma, Hongbing Shao, Yeong Yik Sung, Wen Jye Mok, Li Lian Wong, Yu-Zhong Zhang, Andrew McMinn, Min Wang, Jinyan Xing
Summary: A novel marine phage vB_VhaP_PG11 infecting Vibrio hangzhouensis was isolated from offshore waters of Qingdao, China. It is a double-stranded DNA phage and is related to two Vibrio phages with low homology. Phylogenetic analysis revealed that vB_VhaP_PG11 belongs to a new genus named Qingschitovirus in Schitoviridae. This study provides important information for understanding the interactions between Vibrio phages and their hosts and analyzing unknown viral sequences in metagenomic databases.
FRONTIERS IN MARINE SCIENCE
(2023)
Article
Virology
Fuyue Ge, Ruizhe Guo, Yantao Liang, Ying Chen, Hongbing Shao, Yeong Yik Sung, Wen Jye Mok, Li Lian Wong, Andrew Mcminn, Min Wang
Summary: A novel Stutzerimonas stutzeri phage, vB_PstS_ZQG1, was isolated from the surface seawater of Qingdao, China. It has a unique morphology and genomic sequence, and shows low similarity with previously isolated phages or uncultured viruses, suggesting it belongs to a novel viral genus.
Article
Marine & Freshwater Biology
Kaiyang Zheng, Yue Dong, Yantao Liang, Yundan Liu, Xinran Zhang, Wenjing Zhang, Ziyue Wang, Hongbing Shao, Yeong Yik Sung, Wen Jye Mok, Li Lian Wong, Andrew McMinn, Min Wang
Summary: This study systematically analyzed the genomes, taxonomic features, and distribution patterns of Pseudoalteromonas phages. A total of 143 Pseudoalteromonas-associated phage genomes were identified and assigned to 47 viral clusters. The prevalence of integrated proviruses and filamentous phages suggest the viral lysogenic life cycle in Pseudoalteromonas. These phages play a role in marine biogeochemical cycles and their abundance and distribution vary across polar areas and the deep sea. This study expands our understanding of marine Pseudoalteromonas phages and their interactions with their hosts.
MARINE LIFE SCIENCE & TECHNOLOGY
(2023)
Review
Pharmacology & Pharmacy
Gul-e-Saba Chaudhry, Abdah Md Akim, Naila Safdar, Azra Yasmin, Shaheen Begum, Yeong Yik Sung, Tengku Sifzizul, Tengku Muhammad
Summary: Analysis of cancer biomarkers has great potential in advancing our understanding of diseases at the molecular level and improving the accuracy and timeliness of diagnosis and follow-up care. Researchers are interested in using optical biosensors as a potential tool for early disease diagnosis. There is ongoing progress in the design of biosensors using various concepts.
JOURNAL OF ADVANCED PHARMACEUTICAL TECHNOLOGY & RESEARCH
(2022)