Article
Plant Sciences
Inkyu Park, Jun-Ho Song, Sungyu Yang, Sungwook Chae, Byeong Cheol Moon
Summary: Trichosanthes is a genus of Cucurbitaceae with medicinal value, commonly used in Korean traditional herbal medicines. Despite their herbal applications, genomic information of the genus is limited. This study aims to evaluate the taxonomy of Trichosanthes and provide molecular markers specific for different varieties to prevent confusion and adulteration in commercial medicinal products.
FRONTIERS IN PLANT SCIENCE
(2021)
Article
Multidisciplinary Sciences
Jinkwan Jo, Min-Young Kang, Kyung Seok Kim, Hye Rim Youk, Eun-Jo Shim, Hongsup Kim, Jee-Soo Park, Sung-Chur Sim, Byung Cheon Yu, Jin-Kee Jung
Summary: In this study, improvements were made to the investigation method for plant variety protection by utilizing core single nucleotide polymorphism markers in a high-throughput genotyping system. The results showed that the core marker sets could effectively identify different cabbage varieties and traits, and they were used in practical applications in related fields.
SCIENTIFIC REPORTS
(2022)
Article
Biotechnology & Applied Microbiology
Juanjuan Feng, Xuexian Zhang, Meng Zhang, Liping Guo, Tingxiang Qi, Huini Tang, Haiyong Zhu, Hailin Wang, Xiuqin Qiao, Chaozhu Xing, Jianyong Wu
Summary: This study successfully located the restore gene Rf(2) within a candidate interval of 1.48Mb on chromosome D05 by investigating fertility ratios, using BSA resequencing technology, high-throughput SNP genotyping, and InDel markers. The study also found that InDel markers co-segregated with Rf(2), enhancing the selection of the restorer line.
Article
Chemistry, Analytical
Jeevitha Shanmughanandhan, Dhivya Shanmughanandhan, Subramanyam Ragupathy, Thomas A. Henry, Steven G. Newmaster
Summary: The study successfully developed a species-specific hydrolysis probe assay for raw materials and powders of A. racemosa, demonstrating 100% specificity, 99% efficiency, and 100% reliability in identifying the target species.
JOURNAL OF AOAC INTERNATIONAL
(2021)
Review
Food Science & Technology
Mina Allameh, V. Orsat
Summary: Anxiety is a disorder that can be managed with a combination of therapies or the use of complementary and alternative medicine. Scientists are searching for natural anxiolytics and have identified several medicinal plants with active components. However, further studies are needed to minimize side effects and enhance effectiveness. The use of natural anxiolytics can be improved by managing preparation protocols.
FOOD REVIEWS INTERNATIONAL
(2023)
Article
Biotechnology & Applied Microbiology
Mengge Wang, Guanglin He, Shuang Gao, Fuquan Jia, Xing Zou, Jing Liu, Shouyu Wang, Ziwei Ye, Yiping Hou, Zheng Wang
Summary: The study found that modern Mongolian populations have close genetic proximity to geographically northern East Asians, while also possessing relatively less Hainan Li-related ancestry and more northern East Asian-related ancestry.
Article
Plant Sciences
Kun-Li Xiang, Wei Mao, Huan-Wen Peng, Andrey S. Erst, Ying-Xue Yang, Wen-Chuang He, Zhi-Qiang Wu
Summary: This study sequenced and analyzed the plastid genomes of two Thalictrum species, revealing the phylogenetic relationships within the genus and identifying highly variable noncoding regions that can be used for molecular identification and phylogenetic studies.
FRONTIERS IN PLANT SCIENCE
(2022)
Article
Plant Sciences
Ji-Man Heo, Chang-Ho Eun, In-Jung Kim
Summary: This study reports a new mutant, Ara-unshiu, with a unique late fruit ripening phenotype. Whole genome re-sequencing and functional annotation were used to identify and characterize single nucleotide polymorphism (SNP) and insertion/deletion (InDel) variants in Ara-unshiu. The findings provide insights into fruit ripening mechanisms and tools for molecular breeding of citrus varieties.
Review
Oncology
Yu-Yao Wu, Yan-Ming Xu, Andy T. Y. Lau
Summary: Recent research has shown that traditional herbal medicine has the potential to modify the epigenome and treat chronic diseases such as cancer, diabetes, and inflammation. Understanding the effect of herbal medicine on the epigenome may lead to new therapeutic approaches and diagnostics for human diseases.
CLINICAL EPIGENETICS
(2023)
Review
Engineering, Chemical
Pavitra Murthy, Nur Adania Shaibie, Chooi Ling Lim, Anna Pick Kiong Ling, Soi Moi Chye, Rhun Yian Koh
Summary: Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease characterized by interstitial lung scarring. Herbal medicines, such as Traditional Chinese Medicine (TCM), have shown promise as alternative treatments for IPF due to their natural properties and therapeutic effects.
Article
Biotechnology & Applied Microbiology
Gen Pan, Zheng Li, Siqi Huang, Jie Tao, Yaliang Shi, Anguo Chen, Jianjun Li, Huijuan Tang, Li Chang, Yong Deng, Defang Li, Lining Zhao
Summary: A genome-wide analysis of InDel polymorphisms in Chinese Cannabis was conducted, revealing significant genetic variability and accurate sex identification using sex-linked InDel markers. This study provides valuable information for genetic improvement and conservation of Cannabis germplasm in China.
Article
Medicine, Research & Experimental
Jie Sun, Jiangong Ren, Xuejian Hu, Yuanhua Hou, Yan Yang
Summary: With the improvement of people's living standards and changes in the environment, the incidence of diabetes has rapidly increased, becoming one of the main diseases threatening the health of modern people. Although existing treatment methods can control symptoms and delay disease progression, they have not significantly improved quality of life for patients. Chinese herbal medicines and their extracts, combining traditional experience with modern scientific research, are expected to bring a qualitative leap in the clinical management of diabetes.
BIOMEDICINE & PHARMACOTHERAPY
(2021)
Review
Chemistry, Multidisciplinary
Mayang Kusuma Dewi, Anis Yohana Chaerunisaa, Muhaimin Muhaimin, I. Made Joni
Summary: Phytochemicals or secondary metabolites are substances produced by plants that have shown various biological activities, providing a scientific basis for the use of herbs in traditional medicine. Although herbal medicines are considered to be safe and cost-effective, they have disadvantages such as low solubility, stability, and bioavailability. In recent years, nanotechnology-based herbal drug formulations have gained attention for their enhanced activity and potential in overcoming these issues.
Article
Agronomy
Weijun Ye, Yong Yang, Peiran Wang, Yin Zhang, Liya Zhang, Dongfeng Tian, Lei Zhang, Lingling Zhang, Bin Zhou
Summary: This study elucidated the genetic mechanisms regulating key traits in mung beans and identified QTLs associated with these traits through construction of a genetic linkage map. Candidate gene analysis revealed sequence variations and expression level differences that could aid in cloning of QTLs and marker-assisted selection. Additionally, key regulators for specific traits were identified through genotype and phenotype analysis of 30 mung bean accessions.
MOLECULAR BREEDING
(2021)
Article
Integrative & Complementary Medicine
Jillian L. Capodice, Barbara M. Chubak
Summary: Traditional Chinese Medicine (TCM) is a comprehensive medical system that has been developed over thousands of years and is utilized in the treatment of COVID-19. This paper highlights the use of TCM in treating COVID-19, discussing concepts and challenges of integrating TCM into medical settings.
Article
Biochemistry & Molecular Biology
Sueun Lee, Young Hye Seo, Jun Ho Song, Wook Jin Kim, Ji Hye Lee, Byeong Cheol Moon, Mary Jasmin Ang, Sung Ho Kim, Changjong Moon, Jun Lee, Joong Sun Kim
Summary: The study showed that the water extract of Protaetia brevitarsis seulensis (PBWE) has a significant therapeutic effect against trimethyltin-induced seizures and hippocampal neurodegeneration, likely through its antioxidative properties. Furthermore, six major compounds isolated from PBWE, including inosine and benzoic acid, were confirmed to have essential antioxidative activity, suggesting the potential pharmacotherapeutic use of PBWE in neurodegenerative diseases such as seizures or epilepsy.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Plant Sciences
Min-Jung Kong, Jun-Ho Song, Suk-Pyo Hong
Summary: Pollen morphology plays a crucial role in defining taxa within Persicaria section Cephalophilon and related species, with aperture types, pollen size, and detailed exine ornamentation being key distinguishing features. The presence or absence of orbicules, along with characteristics such as pollen shape and surface texture, provide additional evidence for clarifying taxonomic positions within the studied taxa of Koenigia. Overall, these findings highlight the systematic importance of pollen characteristics in distinguishing between taxa and supporting taxonomic classifications.
PLANT SYSTEMATICS AND EVOLUTION
(2021)
Article
Plant Sciences
JUN-HO SONG, SUK-PYO HONG
Summary: This study presented a taxonomic revision of the genus Sorbaria with a new infrageneric classification, recognizing four species and five varieties. The classification was based on morphological, micromorphological, and palynological evidence.
Article
Biochemistry & Molecular Biology
Seung Mok Ryu, Hyeon-hwa Nam, Joong Sun Kim, Jun-ho Song, Young Hye Seo, Hyo Seon Kim, A. Yeong Lee, Wook Jin Kim, Dongho Lee, Byeong Cheol Moon, Jun Lee
Summary: Three new N-acetyldopamine derivatives were isolated from Tenodera angustipennis egg cases, showing strong antioxidant activities, with compound 2 displaying the highest activity. Additionally, compounds 1a, 1b, and 2 also exhibited the ability to inhibit intracellular reactive oxygen species.
Article
Genetics & Heredity
Endang Rahmat, Inkyu Park, Youngmin Kang
Summary: The new yeast strain Metschnikowia persimmonesis KCTC 12991 BP demonstrates strong antimicrobial activity, potentially linked to secondary metabolites in its genome. Following high-quality whole-genome assembly, M. persimmonesis is identified as a novel species within the Metschnikowia genus.
G3-GENES GENOMES GENETICS
(2021)
Article
Plant Sciences
Inkyu Park, Jun-Ho Song, Sungyu Yang, Sungwook Chae, Byeong Cheol Moon
Summary: Trichosanthes is a genus of Cucurbitaceae with medicinal value, commonly used in Korean traditional herbal medicines. Despite their herbal applications, genomic information of the genus is limited. This study aims to evaluate the taxonomy of Trichosanthes and provide molecular markers specific for different varieties to prevent confusion and adulteration in commercial medicinal products.
FRONTIERS IN PLANT SCIENCE
(2021)
Article
Genetics & Heredity
Inkyu Park, Junho Song, Sungyu Yang, Goya Choi, Byeongcheol Moon
Summary: Sanguisorba, commonly known as burnet, is a plant genus in the Rosaceae family native to temperate regions of the Northern hemisphere, with five species in Korea. Despite being a medicinal remedy in Chinese and Korean Herbal Pharmacopeias, there is still uncertainty about the morphological, genomic, and genetic characteristics of Sanguisorba. The comprehensive study revealed diagnostic values in floral micromorphology, palynology, and complete chloroplast genome analysis, leading to the development of new DNA barcodes for species identification. This study provides valuable information for future research on S. officinalis, positioning it as an important medicinal resource.
Article
Biodiversity Conservation
Min-Kyeong Oak, Sungyu Yang, Goya Choi, Jun-Ho Song
Summary: The floral micromorphology and pollen morphology of two Leonurus species were examined and compared through scanning electron microscopy, revealing potential diagnostic and taxonomic value for further studies in floral biology and taxonomy. The presence of specific trichome types on the adaxial side of the lip and unique features of pollen grains suggest a close association with plant-pollinator interactions and effective pollination.
Article
Multidisciplinary Sciences
Min-Kyeong Oak, Sungyu Yang, Goya Choi, Jun-Ho Song
Summary: The pollen of Piperales varies in size, with consistent aperture types and exine ornamentation within genera. Orbicules, minute sporopollenin granules, may be a possible ancestral characteristic of Piperales. The cluster analysis results using palynological characters are generally congruent with the known molecular phylogeny of Piperales.
SCIENTIFIC REPORTS
(2022)
Article
Biodiversity Conservation
Young Moon Kim, Shukherdorj Baasanmunkh, Jun-Ho Song, Sungyu Yang, Dong Chan Son, Hyeok Jae Choi
Summary: The genus Philadelphus in South Korea was critically revised based on morphological characteristics and it was found that certain features are insufficient for species recognition. Several synonyms were confirmed and a species was excluded from the Korean flora.
JOURNAL OF ASIA-PACIFIC BIODIVERSITY
(2022)
Article
Biochemistry & Molecular Biology
Inkyu Park, Bokyung Choi, Hanna Weiss-Schneeweiss, Soonku So, Hyeon-Ho Myeong, Tae-Soo Jang
Summary: This study conducted comparative analyses on the karyotypes of three Iris species in Korea, with an emphasis on the number and localization of 5S and 35S rDNA loci using FISH. The chloroplast genomes of the same individuals were also sequenced and compared. The results provide important insights into the origin of the progenitor species and the genomes of Iris series Chinenses.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Plant Sciences
Jun-Ho Song, Hyeon-Hwa Nam, Inkyu Park, Sungyu Yang, Jin Mi Chun, Yun-Soo Seo, Hyun-Yong Kim, Byeong Cheol Moon, Sohi Kang, Changjong Moon, Seong-IL Kang, Ji Hoon Song, Joong-Sun Kim
Summary: This study investigated the morphological and micromorphological differences between Agastache rugosa grown on islands and inland areas, as well as their pharmacological effects on gastritis. The results showed that island A. rugosa had smaller plants and leaves but higher density of trichomes compared to inland A. rugosa. Analysis of essential oil components revealed higher levels of pulegone in island A. rugosa. Both island and inland A. rugosa effectively reduced gastric damages and expression of inflammatory protein. The study suggests that there are quantitative differences between island and inland plants, but their gastritis-inhibitory effects are similar.
Article
Plant Sciences
Kyu-Chan Shim, Yuna Kang, Jun-Ho Song, Ye Jin Kim, Jae Kwang Kim, Changsoo Kim, Thomas H. Tai, Inkyu Park, Sang-Nag Ahn
Summary: In this study, a lethal, chlorophyll-deficient, yellow seedling (YS) phenotype was identified in the progeny of a backcross between a Korean japonica variety and another rice variety. The mutant phenotype was consistent with a recessive mutation and was characterized by loosely arranged mesophyll cells and the absence of chloroplast development. A 2-bp deletion in the OsCHLI gene, which encodes a subunit of magnesium-chelatase, was identified as the cause of the phenotype.
Article
Horticulture
Sungyu Yang, Goya Choi, Jun-Ho Song
Summary: This study analyzed the morphological, anatomical, micromorphological, and palynological characteristics of D. mariesii and presented an expanded and updated description. The obtained results provide systematic data for the phylogeny of Davalliaceae and establish a basis for future taxonomic delimitation.