Region-specific blood–brain barrier transporter changes leads to increased sensitivity to amisulpride in Alzheimer’s disease
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Title
Region-specific blood–brain barrier transporter changes leads to increased sensitivity to amisulpride in Alzheimer’s disease
Authors
Keywords
-
Journal
Fluids and Barriers of the CNS
Volume 16, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2019-12-17
DOI
10.1186/s12987-019-0158-1
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- (2018) Amer Alam et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2017) Massoud Saidijam et al. XENOBIOTICA
- Organic cation transporter 1 (OCT1) is involved in pentamidine transport at the human and mouse blood-brain barrier (BBB)
- (2017) Gayathri N. Sekhar et al. PLoS One
- The transporter and permeability interactions of asymmetric dimethylarginine (ADMA) and L-arginine with the human blood–brain barrier in vitro
- (2016) Christopher P. Watson et al. BRAIN RESEARCH
- In-depth neuropharmacokinetic analysis of antipsychotics based on a novel approach to estimate unbound target-site concentration in CNS regions: link to spatial receptor occupancy
- (2016) I Loryan et al. MOLECULAR PSYCHIATRY
- A population approach to characterise amisulpride pharmacokinetics in older people and Alzheimer’s disease
- (2016) Suzanne Reeves et al. PSYCHOPHARMACOLOGY
- Blood-Brain Barrier Leakage in Patients with Early Alzheimer Disease
- (2016) Harm J. van de Haar et al. RADIOLOGY
- Effects of lipopolysaccharide on the expression of plasma membrane monoamine transporter (PMAT) at the blood-brain barrier and its implications to the transport of neurotoxins
- (2015) Kuo-Chen Wu et al. JOURNAL OF NEUROCHEMISTRY
- The problem of genotype and sex differences in life expectancy in transgenic AD mice
- (2015) Eric A. Rae et al. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
- The Poorly Membrane Permeable Antipsychotic Drugs Amisulpride and Sulpiride Are Substrates of the Organic Cation Transporters from the SLC22 Family
- (2014) Joao N. Dos Santos Pereira et al. AAPS Journal
- Haloperidol-loaded intranasally administered lectin functionalized poly(ethylene glycol)–block-poly(d,l)-lactic-co-glycolic acid (PEG–PLGA) nanoparticles for the treatment of schizophrenia
- (2014) Justin Piazza et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Towards a therapeutic window of D2/3 occupancy for treatment of psychosis in Alzheimer's disease, with [18F]fallypride positron emission tomography
- (2014) Chloe Clark-Papasavas et al. INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY
- Activity of P-Glycoprotein, a -Amyloid Transporter at the Blood-Brain Barrier, Is Compromised in Patients with Mild Alzheimer Disease
- (2014) A. K. Deo et al. JOURNAL OF NUCLEAR MEDICINE
- Aβ1–42 reduces P-glycoprotein in the blood–brain barrier through RAGE–NF-κB signaling
- (2014) R Park et al. Cell Death & Disease
- Multidrug and toxin extrusion proteins (MATE/SLC47); role in pharmacokinetics
- (2013) Frantisek Staud et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Estimating Dopamine D2 Receptor Occupancy for Doses of 8 Antipsychotics
- (2013) Irene M. Lako et al. JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY
- Lysosomal Membrane Proteins and Their Central Role in Physiology
- (2013) Michael Schwake et al. TRAFFIC
- Transport of Biogenic Amine Neurotransmitters at the Mouse Blood–Retina and Blood–Brain Barriers by Uptake1 and Uptake2
- (2012) Pascal André et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Discovery of Potent, Selective Multidrug and Toxin Extrusion Transporter 1 (MATE1, SLC47A1) Inhibitors Through Prescription Drug Profiling and Computational Modeling
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- (2012) Daniëlle M. E. van Assema et al. MOLECULAR IMAGING AND BIOLOGY
- Quantitative Targeted Absolute Proteomic Analysis of Transporters, Receptors and Junction Proteins for Validation of Human Cerebral Microvascular Endothelial Cell Line hCMEC/D3 as a Human Blood–Brain Barrier Model
- (2012) Sumio Ohtsuki et al. MOLECULAR PHARMACEUTICS
- In vitro P-glycoprotein efflux inhibition by atypical antipsychotics is in vivo nicely reflected by pharmacodynamic but less by pharmacokinetic changes
- (2012) Ulrich Schmitt et al. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
- Lamotrigine is a substrate for OCT1 in brain endothelial cells
- (2011) David Dickens et al. BIOCHEMICAL PHARMACOLOGY
- Beta amyloid effects on expression of multidrug efflux transporters in brain endothelial cells
- (2011) Katarzyna D. Kania et al. BRAIN RESEARCH
- The transport of nifurtimox, an anti-trypanosomal drug, in an in vitro model of the human blood–brain barrier: Evidence for involvement of breast cancer resistance protein
- (2011) Christopher P. Watson et al. BRAIN RESEARCH
- Quantitative targeted absolute proteomics of human blood-brain barrier transporters and receptors
- (2011) Yasuo Uchida et al. JOURNAL OF NEUROCHEMISTRY
- AGNP Consensus Guidelines for Therapeutic Drug Monitoring in Psychiatry: Update 2011
- (2011) C. Hiemke et al. PHARMACOPSYCHIATRY
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- (2010) Hasini C. Wijesuriya et al. BRAIN RESEARCH
- Amisulpride - dose, plasma concentration, occupancy and response: implications for therapeutic drug monitoring
- (2009) A. Sparshatt et al. ACTA PSYCHIATRICA SCANDINAVICA
- Increased Antipsychotic Sensitivity in Elderly Patients
- (2009) Hiroyuki Uchida et al. JOURNAL OF CLINICAL PSYCHIATRY
- Involvement of Human Multidrug and Toxin Extrusion 1 in the Drug Interaction between Cimetidine and Metformin in Renal Epithelial Cells
- (2009) M. Tsuda et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Pentamidine Movement across the Murine Blood-Brain and Blood-Cerebrospinal Fluid Barriers: Effect of Trypanosome Infection, Combination Therapy, P-Glycoprotein, and Multidrug Resistance-Associated Protein
- (2009) L. Sanderson et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Identification of Novel Specific and General Inhibitors of the Three Major Human ATP-Binding Cassette Transporters P-gp, BCRP and MRP2 Among Registered Drugs
- (2009) Pär Matsson et al. PHARMACEUTICAL RESEARCH
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- The human brain endothelial cell line hCMEC/D3 as a human blood-brain barrier model for drug transport studies
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- Amisulpride the ‘atypical’ atypical antipsychotic — Comparison to haloperidol, risperidone and clozapine
- (2008) Sridhar Natesan et al. SCHIZOPHRENIA RESEARCH
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