Article
Food Science & Technology
Dilara Yalmanci, Humeyra Ispirli, Enes Dertli
Summary: In this study, 17 LAB strains were isolated from pre-fermented liquids of different cereals and legumes, with two strains identified as the highest EPS producers. The EPSs from Weissella confusa W-16 and Leuconostoc lactis GW-6 were found to contain (1->3)-linked alpha-D-glucose units. Various analyses confirmed the structure and characteristics of the dextrans produced by these strains.
Article
Fisheries
Yimin Chen, Peili Gao, Xu Tang, Changan Xu
Summary: Antarctica is home to special extremophiles, with a cold-adapted bacterium identified as a potential candidate for exopolysaccharides production. Physiochemistry, bioactivities, and potential antioxidant properties of the produced EPS were evaluated, showing promising applications in aquaculture for enhancing immunity and enzyme activities in fish.
Article
Food Science & Technology
Jae Young Sim, Maryam Enteshari, Kaavya Rathnakumar, Sergio Martinez-Monteagudo
Summary: This study demonstrated the feasibility of using hydrodynamic cavitation to manufacture ice cream with reduced stabilizer, resulting in changes in particle size, rheological behavior, and melting characteristics of the ice cream. The cavitation process significantly altered the structure of the ice cream, potentially leading to the development of novel frozen dessert structures.
INNOVATIVE FOOD SCIENCE & EMERGING TECHNOLOGIES
(2021)
Review
Biotechnology & Applied Microbiology
Andres Garcia, Marco T. Fernandez-Sandoval, Daniel Morales-Guzman, Fernando Martinez-Morales, Maria R. Trejo-Hernandez
Summary: In recent years, novel marine bacterial exopolysaccharides (EPS) with various potential applications have been discovered. Marine bacteria rely on EPS to adapt to the extreme environment of the ocean ecosystem. However, high production cost is the major challenge for commercial application.
JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Xuefang Zhao, Qi Liang
Summary: This study optimized the production of exopolysaccharides (EPS) from Lactiplantibacillus plantarum MC5 (Lp. plantarum MC5), evaluated its resistance to digestive juices, antioxidant activity, and rheological properties. The results showed that the maximum EPS production was achieved under specific conditions. The EPS-MC5 exhibited high resistance to digestive enzymes and antioxidant activity, as well as favorable rheological properties. These findings contribute to the understanding and potential applications of EPS in human health and functional foods.
Article
Food Science & Technology
Sally S. S. Sakr, Sahar H. S. Mohamed, Asmahan A. A. Ali, Waheeba E. E. Ahmed, Reham M. M. Algheshairy, Mona S. S. Almujaydil, Ahmed A. A. Al-Hassan, Hassan Barakat, Mohamed F. Y. Hassan
Summary: The feasibility of manufacturing a new flavored ice cream using Adansonia digitata L. (Baobab) fruit pulp (ADFP) to improve its nutritional value and color was examined. Replacing skim milk powder with ADFP did not significantly impact the chemical characteristics of the ice cream samples, except for protein and ash content which decreased as ADFP levels increased. Increasing ADFP levels significantly increased antioxidant levels and improved the color of the samples.
Article
Engineering, Environmental
Morten Kam Dahl Dueholm, Maaike Besteman, Emil Juel Zeuner, Marie Riisgaard-Jensen, Morten Eneberg Nielsen, Sofie Zacho Vestergaard, Soren Heidelbach, Nicolai Sundgaard Bekker, Per Halkjaer Nielsen
Summary: A study investigated the genomic potential for exopolysaccharide biosynthesis in bacterial species typical in activated sludge (AS) systems based on genome mining and gene synteny analyses. Putative gene clusters associated with the biosynthesis of various exopolysaccharides were identified in AS bacteria. This study provides a comprehensive overview of the genome-resolved potential for these exopolysaccharides in AS bacteria and contributes to a better understanding of EPS composition in wastewater treatment systems.
Review
Polymer Science
Vishal Ahuja, Arvind Kumar Bhatt, J. Rajesh Banu, Vinod Kumar, Gopalakrishnan Kumar, Yung-Hun Yang, Shashi Kant Bhatia
Summary: Microbial exopolysaccharides (EPSs) such as xanthan, dextran, gellan, and curdlan have various applications in industries due to their biocompatibility, nontoxicity, and functional characteristics. However, their commercial use in healthcare practices is hindered by biodegradability issues, poor cell adhesion, mineralization, and low enzyme activity. Blending EPSs with other polymers can improve their characteristics and make the composites suitable for diverse applications, especially tissue engineering. More research is needed to address the challenges and commercialize these products.
Article
Food Science & Technology
Chan Won Seo, Nam Su Oh
Summary: The conjugation of kappa-carrageenan (kappa-Car) with milk protein isolate (MPI) through the Maillard reaction was found to be an effective stabilizer for ice cream products. The addition of the kappa-Car/MPI conjugate improved the physical stability and resistance to melting of the ice cream, without significantly affecting its overrun and hardness values.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2022)
Article
Food Science & Technology
Suchismita Roy, Shaik Abdul Hussain, Writdhama G. Prasad, Yogesh Khetra
Summary: The study on improving the quality of high protein ice cream by increasing PS80 level revealed that higher PS80 levels decreased the rheological properties, increased the size of fat globule clumps and affected the hardness values. Sensory evaluation showed that ice cream samples with 40% PS80 in the emulsifier blend received the highest preference among panelists.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2021)
Article
Food Science & Technology
Yanmeng Lu, Shengyi Han, Shuobo Zhang, Kaicen Wang, Longxian Lv, David Julian McClements, Hang Xiao, Bjorn Berglund, Mingfei Yao, Lanjuan Li
Summary: This study investigated the impact of gastrointestinal factors on the surface properties of two probiotics, and found that exopolysaccharides (EPS) play an important role in the mucoadhesive behavior of probiotics. Gastric acids decrease the adhesive forces, while bile salts increase the adhesive forces. Additionally, the molecular weight of purified EPS in probiotics also influences the mucoadhesive behavior.
CURRENT RESEARCH IN FOOD SCIENCE
(2022)
Review
Chemistry, Applied
Xinyang Sun, Simiao Wu, Wen Li, Filiz Koksel, Yifei Du, Lei Sun, Yong Fang, Qiuhui Hu, Fei Pei
Summary: Cooperative fermentation by yeast and lactic acid bacteria (CFYL) can improve the rheology of whole wheat flour dough (WWFD) and enhance the quality of bread. CFYL-induced production of exopolysaccharides (EPSs), enzymes, and organic acids modifies the structure of the dough, strengthens the gluten network, and enhances the interactions between proteins and starch. Additionally, CFYL increases the content of water-extractable arabinoxylans and soluble wheat proteins while decreasing the size of starch granules, leading to improved gas cell retention and stabilization in WWFD during breadmaking.
FOOD HYDROCOLLOIDS
(2023)
Article
Agriculture, Dairy & Animal Science
M. Brighenti, S. Govindasamy-Lucey, J. J. Jaeggi, M. E. Johnson, J. A. Lucey
Summary: This study investigated the rheological and textural properties of cream cheeses manufactured by substituting sweet cream with various levels of whey cream. The results showed that high levels of whey cream led to lower firmness and higher stickiness in cream cheeses, making them softer and more spreadable.
JOURNAL OF DAIRY SCIENCE
(2021)
Article
Biochemistry & Molecular Biology
Yunan Ma, Mengshi Zhao, Fan Zhou, Xuan Liu, Changhong Liu
Summary: This study presents the first evidence of anaerobic exopolysaccharide (EPS) synthesis by the fungus Schizophyllum commune 20R-7-F01, isolated from coal-bearing sediments 2.0 km below the seafloor. The fungus exhibited significantly higher specific EPS production under anaerobic conditions compared to aerobic conditions. Transcriptomic analysis revealed differentially expressed genes associated with carbon metabolism pathways, highlighting the oxygen-dependent regulation of EPS synthesis and suggesting its importance for fungal adaptation to anaerobic environments.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Biotechnology & Applied Microbiology
Daniel Joe Dailin, Shanmugaprakasham Selvamani, Khaw Michelle, Yanti Maslina Mohd Jusoh, Lai Fatt Chuah, Awais Bokhari, Hesham Ali El Enshasy, Muhammad Mubashir, Pau Loke Show
Summary: This study optimized the submerged cultivation of L. reuteri strain DSM 20016 (T) to increase the production of crude EPS. Through experimental design and modeling analysis, sucrose, yeast extract, and sodium acetate were identified as important factors impacting crude EPS production. Under optimal fermentation conditions, the strain was able to produce a significant amount of high-quality crude EPS.
BIOCHEMICAL ENGINEERING JOURNAL
(2022)
Article
Food Science & Technology
Abdullah Baycar, Nevzat Konar, Hamza Goktas, Osman Sagdic, Derya Genc Polat
Summary: This study investigates the possibility of using spread (SC) and compound chocolate (CC) as carriers of betalains. The addition of beetroot powder significantly affects the quality parameters and visual properties of both SC and CC. It is found that the hardness and plastic viscosity values of CC increase with the amount of beetroot powder, while other properties remain unchanged. In addition, the use of beetroot powder decreases the color values of the samples and increases the redness associated with the pigment source.
FOOD SCIENCE AND TECHNOLOGY
(2022)
Article
Food Science & Technology
Kubra Ozkan, Hatice Bekiroglu, Yuksel Bayram, Osman Sagdic, Sabri Erbas
Summary: This study investigated the antioxidant and antibacterial activities of safflower extracts from different genotypes, as well as their bioaccessibility after in vitro gastrointestinal digestion. The results showed that safflower extracts exhibited potent antioxidant and antibacterial activities, and were important in terms of the bioavailability of bioactive compounds.
FOOD SCIENCE AND TECHNOLOGY
(2022)
Review
Food Science & Technology
Erenay Eren, Necattin Cihat Icyer, Nevruz Berna Tatlisu, Mahmut Kilicli, Gizem Hulaga Kaderoglu, Omer Said Toker
Summary: Hunger and poverty reduction is one of the primary goals set by the United Nations in the new century. Legumes, as a valuable nutritional resource, play an important role in addressing hunger and providing nutritious food. Recycling legume waste contributes to reducing food waste and providing nutritional supplements for vegan and vegetarian diets.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Article
Biotechnology & Applied Microbiology
Meyrem Vehapi, Benan Inan, Selma Kayacan-Cakmakoglu, Osman Sagdic, Didem Ozcimen
Summary: This study investigates the optimization of spore yield of Bacillus subtilis for large-scale production in bioreactors. Bacillus species have advantages in terms of their characteristics and fermentation technology, making them ideal biological control agents. The study also examines the antifungal activity of Bacillus subtilis against pathogenic fungi.
PROBIOTICS AND ANTIMICROBIAL PROTEINS
(2023)
Article
Food Science & Technology
Ayse Karadag, Selma Kayacan Cakmakoglu, Rusen Metin Yildirim, Salih Karasu, Esra Avci, Hayrettin Ozer, Osman Sagdic
Summary: In this study, phenolic compounds from oil mill waste were extracted using lecithin as a surfactant through cloud point extraction. The optimized process conditions were determined and the resulting enriched lecithin showed higher oxidative stability compared to control lecithin. This study provides a new perspective for the recovery of phenolics from waste without using solvents.
JOURNAL OF FOOD PROCESSING AND PRESERVATION
(2022)
Article
Food Science & Technology
Selma Kayacan, Osman Sagdic, Ibrahim Doymaz, Salih Karasu
Summary: This study investigated the effects of FD, USVD, HAD, and IRD methods on the drying behavior, antioxidant activity, phenolic distribution, rehydration capacity, SEM image, and color quality of Asian pear. The results showed that USVD and FD can be used as alternative drying methods with good preservation of quality.
JOURNAL OF FOOD PROCESSING AND PRESERVATION
(2022)
Article
Engineering, Chemical
H. Demircan, O. Sagdic, K. Ozkan, S. Kayacan, A. A. Us, K. Sarioglu, R. A. Oral
Summary: This study investigated the drying kinetics, extraction optimization, total phenolic and flavonoid contents, antioxidant activities, and antimicrobial effects of deer apple fruit. The results showed that deer apple fruit is a good source of phenolic and flavonoid compounds and exhibits antimicrobial activity.
LATIN AMERICAN APPLIED RESEARCH
(2022)
Article
Food Science & Technology
Kubra Ozkan, Ayse Karadag, Osman Sagdic
Summary: The study found that different drying methods for grapes can affect the content and bioaccessibility of phenolic compounds and minerals, with freeze-drying retaining the most phenolic compounds and ultrasound-assisted vacuum-drying causing the highest loss.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2022)
Article
Food Science & Technology
Hatice Bekiroglu, Hamza Goktas, Dila Karaibrahim, Fatih Bozkurt, Osman Sagdic
Summary: Demand for vegan foods has led to the use of plant-based milks, such as walnut milk, in the production of dairy products like ice cream. This study found that using walnut milk significantly affected the physical and chemical properties of ice cream samples, increasing their fat content and improving their rheological properties. Although it decreased the brightness value, walnut milk introduced different volatile compounds to the ice cream samples. Sensory evaluation showed that ice cream samples made with walnut milk were well-liked by the panelists and received similar scores to the control samples. This study demonstrates the potential use of walnut milk in ice cream production.
INTERNATIONAL JOURNAL OF GASTRONOMY AND FOOD SCIENCE
(2022)
Article
Biochemical Research Methods
Selma Kayacan Cakmakoglu, Melike Vurmaz, Emine Bezirci, Yasemin Kaya, Hilal Dikmen, Hamza Goktas, Fatmanur Demirbas, Betul Encu, Esra Acar Soykut, Filiz Alemdar, Ibrahim Cakir, M. Zeki Durak, Muhammet Arici, Osman Sagdic, Mustafa Turker, Enes Dertli
Summary: This study aimed to isolate, identify, and determine the technological characteristics of potential starter cultures from traditional yogurt samples. 19 S. thermophilus and 11 Lb. delbrueckii subsp. bulgaricus strains were identified for further application as starter cultures. The results showed that S. thermophilus strains had higher acidification capacity and Lb. delbrueckii subsp. bulgaricus strains had higher proteolytic activity. Additionally, the strains exhibited low antibiotic resistance.
PREPARATIVE BIOCHEMISTRY & BIOTECHNOLOGY
(2023)
Article
Green & Sustainable Science & Technology
Hande Gokcan, Duygu Ozmen, Meral Yalcin, Enes Dertli, Omer Said Toker, Monika Sujka
Summary: The rheological properties of different dextrans from three LAB strains were determined, and the interactions between dextran PDER21 and maize, wheat, and waxy maize starches were studied. The presence of dextran PDER21 increased the elastic behavior of maize starch and enhanced the elastic properties of wheat and waxy maize starches. Dextran PDER21 also affected the pasting properties of starches, leading to higher viscosity values in certain starch-dextran blends.
Article
Food Science & Technology
Yuksel Bayram, Kubra Ozkan, Osman Sagdic
Summary: In this study, unripe grapes were used to produce verjuice powder, which was encapsulated with maltodextrin and pectin. The powders were evaluated for their properties and retention of phenolic compounds. The results showed that pectin encapsulation had higher phenolic retention compared to maltodextrin encapsulation. This study suggests that waste from viticulture can be transformed into valuable powders for potential applications and contribute to sustainable agriculture.
EUROPEAN FOOD RESEARCH AND TECHNOLOGY
(2023)
Article
Plant Sciences
Tugba Dedebas, Lutfiye Ekici, Osman Sagdic
Summary: This study examined the changes in antioxidant activity and thermal stability of bay laurel, lemon peel, and orange peel essential oils stored at different temperatures. The results showed that the antioxidant and antiradical activity of the oils decreased during storage, especially at elevated temperatures. The volatile oils obtained may have potential as natural antioxidants in food products.
JOURNAL OF ESSENTIAL OIL BEARING PLANTS
(2022)
Article
Food Science & Technology
Huseyin Demircan, Kemal Sarioglu, Osman Sagdic, Kubra Ozkan, Selma Kayacan, Ahmet Abdullah Us, Rasim Alper Oral
Summary: Deer apple, a fruit native to the Mediterranean region, has various uses such as fresh and dried consumption, herbal tea flavoring, vinegar production, and pickling. It is also traditionally used to treat health issues including cholesterol, shortness of breath, diabetes, and hypertension. This study determined the organic acid, phenolic compound, sugar, and aroma composition of deer apple for the first time, revealing the most abundant components such as malic acid, fructose, and various phenolic compounds.
FOOD SCIENCE AND TECHNOLOGY
(2022)
Article
Food Science & Technology
Sefik Tekle, Fatih Bozkurt, Perihan Kubra Akman, Osman Sagdic
Summary: Fish skin gelatin from sea bass can be hydrolyzed to obtain peptide fractions with antioxidant and anticancer activities. The gelatin also has good emulsifying and foaming properties, as well as fat binding capacity.
FOOD SCIENCE AND TECHNOLOGY
(2022)
Review
Chemistry, Applied
Xingran Kou, Dongdong Su, Fei Pan, Xiwei Xu, Qingran Meng, Qinfei Ke
Summary: This review provides a systematic discussion of the application of molecular dynamics (MD) simulations in aroma compounds (ACs)/cyclodextrins (CDs) inclusion complexes (ICs). It covers the establishment of the simulation process, parameter selection, model evaluation, and various application cases, summarizing the major achievements and challenges of this method.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Haoyu Yu, Quanbin Zhang, Ammad Ahmad Farooqi, Jing Wang, Yang Yue, Lihua Geng, Ning Wu
Summary: Brown algae are rich in fucoidan, which has been found to have anti-cancer and anti-metastasis effects. Fucoidan inhibits tumor cell growth, proliferation, and metastasis, and also promotes immune responses in the tumor microenvironment.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Liang Dong, Yanan Li, Hailin Cong, Bing Yu, Youqing Shen
Summary: Gene therapy is a revolutionary treatment that requires suitable vectors for protecting and releasing exogenous nucleic acids in target cells. Chitosan, as a non-viral vector, has gained attention due to its good biocompatibility and ability to load large amounts of nucleic acids. This paper summarizes the potential of chitosan and its derivatives as gene delivery vector materials, discusses factors influencing transfection efficiency, performance evaluation, ways to optimize infectious efficiency, and current research development directions. It also provides an outlook on the future prospects of chitosan.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ana Iglesias-Mejuto, Beatriz Magarinos, Tania Ferreira-Goncalves, Ricardo Starbird-Perez, Carmen Alvarez-Lorenzo, Catarina Pinto Reis, Ines Ardao, Carlos A. Garcia-Gonzalez
Summary: This study developed a novel processing strategy to manufacture drug-loaded and personalized aerogels with nanostructures. The aerogels demonstrated bioactivity and antimicrobial effects, promoting bone regeneration and preventing infections in bone tissue engineering.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Zhenxu Shi, Dimei Yang, Yan Zhou, Xinyu Chen, Lin Gan, Jin Huang
Summary: This study proposes a micro-assembly method to improve the photoluminescent properties of crystalline cellulose nanocrystals (CNCs) by organizing them within a sub-micrometer-sized metal-organic framework and coating with TiO2. The TiO2 coating prevents CNC assembly breakdown and allows information to be revealed using screenprinted labels for anti-counterfeiting purposes.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Xuejiao Liu, Bin Fu, Jierong Chen, Zhenyu Sun, Dongdong Zheng, Zhonghua Li, Bing Gu, Ying Zhang, Haojie Lu
Summary: Liver disease is a major cause of global mortality, and identifying biomarkers for diagnosing its progression is crucial for improving outcomes. Targeted mass spectrometry is a powerful tool for verifying biomarker candidates and clinical applications, particularly for glycoproteins translation. However, the limitation of analyzing only one sample per run has become apparent. In this study, a high-throughput intact N-glycopeptides quantification strategy was developed, allowing the validation of 20 samples per run with an average analysis time of 3 minutes per sample. The strategy was applied in a cohort of 461 serum samples and identified a panel of 10 IgG N-glycopeptides that have strong clinical utility in evaluating the severity of liver disease.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Qian Wang, Hao Jiang, Hongli Zhang, Weiqiao Lu, Xiao Wang, Wenfeng Xu, Jia Li, Youjing Lv, Guoyun Li, Chao Cai, Guangli Yu
Summary: This study proposes a novel strategy of antibody-beta-glucan conjugates (AGC) to enhance the antitumor immune response to immune checkpoint blockade (ICB) therapy. AGC demonstrated powerful tumor suppression and promoted interaction between tumor cells and dendritic cells (DCs), thereby enhancing immunotherapeutic benefits.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Chaeyeon Lee, Sojeong Lee, Sang Wook Kang
Summary: The study aims to enhance the properties of porous membranes by addressing the limitations associated with phase separation. By using cellulose acetate and citric acid, the researchers were able to fabricate membranes with improved mechanical strength and thermal stability. The cross-linking effect of citric acid resulted in a more uniform pore structure and higher porosity.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Tejaswini Kolipaka, Giriraj Pandey, Noella Abraham, Dadi A. Srinivasarao, Rajeev Singh Raghuvanshi, P. S. Rajinikanth, Vidya Tickoo, Saurabh Srivastava
Summary: This review focuses on the design and application of polysaccharide-based hydrogel wound dressings, highlighting aspects such as biocompatibility, biodegradability, drug entrapment, moisturizing ability, swelling, and mechanical properties. Additionally, various crosslinking methods and recent developments in stimuli-responsive hydrogels are discussed.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Anqi Xu, Nan Zhang, Shixing Su, Hongyu Shi, Daoqiang Lu, Xifeng Li, Xin Zhang, Xin Feng, Zhuohua Wen, Gengwu Ma, Mengshi Huang, Chi Huang, Yuqi Hu, Hao Yuan, Qinwen Liu, Daogang Guan, Jun Wang, Chuanzhi Duan
Summary: The study presents a one-pot radical polymerization method to fabricate a hydrogel with adhesive properties, which can effectively treat bacterial-infected diabetic wounds and accelerate wound healing.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Montarop Yamabhai, Munthipha Khamphio, Thae Thae Min, Chai Noy Soem, Nguyen Cao Cuong, Waheni Rizki Aprilia, Krisanai Luesukprasert, Karsidete Teeranitayatarn, Atthaphon Maneedaeng, Tina R. Tuveng, Silje B. Lorentzen, Simen Antonsen, Paiboon Jitprasertwong, Vincent G. H. Eijsink
Summary: The study investigates the bioconversion of chitosan into soluble anti-inflammatory chitosan oligosaccharides (CHOS) using an enzyme. The results show that the generated CHOS have anti-inflammatory activity, but the magnitude of the activity depends on the substrate and production process. Different methods of dissolving chitosan also affect the properties of CHOS. The study highlights the importance of quality assurance in CHOS preparations.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Wen Cao, Jiangping Wu, Xinya Zhao, Zixu Li, Jie Yu, Taili Shao, Xuefeng Hou, Lutan Zhou, Chunfei Wang, Guodong Wang, Jun Han
Summary: In this study, a water-soluble polysaccharide (PLP1) was successfully isolated and purified from Pueraria lobata. It was found that PLP1 was composed of specific glycosidic units and exhibited a better free radical-scavenging ability. Moreover, PLP1 effectively protected the liver against acute alcoholic liver disease (ALD) in mice.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ya Su, Yaqian Liu, Xueyan Hu, Yueqi Lu, Jinyuan Zhang, Wenbo Jin, Wang Liu, Yan Shu, Yuen Yee Cheng, Wenfang Li, Yi Nie, Bo Pan, Kedong Song
Summary: A 3D printed scaffold based on carbon dots-curcumin nano-drug release has been developed for drug delivery after breast cancer surgery. The scaffold showed effective inhibition of tumor growth, antibacterial activity, and promotion of wound healing, making it a promising approach for preventing tumor recurrence.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ekaterina Sokolova, Diane Jouanneau, Antonin Chevenier, Murielle Jam, Nathalie Desban, Pierre Colas, Elizabeth Ficko-Blean, Gurvan Michel
Summary: Carrageenans, a compound synthesized in red algae, have various biological properties and are valuable in the pharmaceutical and cosmetic industries. Their fine structure affects wound healing, oxidative processes, hemostasis, and inflammation. Enzymatic modification of carrageenans produces oligosaccharides that bind to natural human serum antibodies and specific antibodies, showing potential for therapeutic applications.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Yan Shi, Miao Yu, Kaijin Qiu, Tiantian Kong, Chunjing Guo, Wenxue Zhang, Daquan Chen, Ming Kong
Summary: In this study, functionalized transfersomes were developed to co-deliver doxorubicin and 1MT towards primary tumors and tumor draining lymph nodes via transdermal administration using microneedles. The results showed that the nano-complexed microneedles exhibited a stronger suppression in tumor growth compared to the intravenous group.
CARBOHYDRATE POLYMERS
(2024)