Antiviral Effectors and Gene Drive Strategies for Mosquito Population Suppression or Replacement to Mitigate Arbovirus Transmission by Aedes aegypti

Development of a confinable gene drive system in the human disease vector Aedes aegypti

(2020) Ming Li et al.   eLife

Genome-Wide Transcriptome Profiling Reveals Genes Associated with Meiotic Drive System of Aedes aegypti

(2019) Dongyoung Shin et al.   Insects

Wolbachia prevalence, diversity, and ability to induce cytoplasmic incompatibility in mosquitoes

(2019) Mathieu Sicard et al.   Current Opinion in Insect Science

Engineered resistance to Zika virus in transgenic Aedes aegypti expressing a polycistronic cluster of synthetic small RNAs

(2019) Anna Buchman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Induction of RNA interference to block Zika virus replication and transmission in the mosquito Aedes aegypti

(2019) Tereza Magalhaes et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

Selection on Aedes aegypti alters Wolbachia-mediated dengue virus blocking and fitness

(2019) Suzanne A. Ford et al.   Nature Microbiology

MGD riv E: A modular simulation framework for the spread of gene drives through spatially explicit mosquito populations

(2019) Héctor M. Sánchez C. et al.   Methods in Ecology and Evolution

Control of RNA viruses in mosquito cells through the acquisition of vDNA and endogenous viral elements

(2019) Michel Tassetto et al.   eLife

Advances in Engineering the Fly Genome with the CRISPR-Cas System

(2018) Ethan Bier et al.   GENETICS

Reducing resistance allele formation in CRISPR gene drive

(2018) Jackson Champer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Recommendations for Laboratory Containment and Management of Gene Drive Systems in Arthropods

(2018) Mark Q. Benedict et al.   VECTOR-BORNE AND ZOONOTIC DISEASES

Advances in Engineering the Fly Genome with the CRISPR-Cas System

(2018) Ethan Bier et al.   GENETICS

SLiM 3: Forward Genetic Simulations Beyond the Wright–Fisher Model

(2018) Benjamin C Haller et al.   MOLECULAR BIOLOGY AND EVOLUTION

Epidemic arboviral diseases: priorities for research and public health

(2017) Annelies Wilder-Smith et al.   LANCET INFECTIOUS DISEASES

Rules of the road for insect gene drive research and testing

(2017) Zach Adelman et al.   NATURE BIOTECHNOLOGY

Germline Cas9 expression yields highly efficient genome engineering in a major worldwide disease vector,Aedes aegypti

(2017) Ming Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Developing standard operating procedures for gene drive research in disease vector mosquitoes

(2017) Zach N. Adelman et al.   Pathogens and Global Health

The creation and selection of mutations resistant to a gene drive over multiple generations in the malaria mosquito

(2017) Andrew M. Hammond et al.   PLoS Genetics

Engineered Aedes aegypti JAK/STAT Pathway-Mediated Immunity to Dengue Virus

(2017) Natapong Jupatanakul et al.   PLoS Neglected Tropical Diseases

Contemporary status of insecticide resistance in the major Aedes vectors of arboviruses infecting humans

(2017) Catherine L. Moyes et al.   PLoS Neglected Tropical Diseases

CRISPR/Cas9 gene drives in genetically variable and nonrandomly mating wild populations

(2017) Douglas W. Drury et al.   Science Advances

Use of transgenicAedes aegyptiin Brazil: risk perception and assessment

(2016) Paulo Paes de Andrade et al.   BULLETIN OF THE WORLD HEALTH ORGANIZATION

SLiM 2: Flexible, Interactive Forward Genetic Simulations

(2016) Benjamin C. Haller et al.   MOLECULAR BIOLOGY AND EVOLUTION

Antiviral Hammerhead Ribozymes Are Effective for Developing Transgenic Suppression of Chikungunya Virus in Aedes aegypti Mosquitoes

(2016) Priya Mishra et al.   Viruses-Basel

Establishment of a Wolbachia Superinfection in Aedes aegypti Mosquitoes as a Potential Approach for Future Resistance Management

(2016) D. Albert Joubert et al.   PLoS Pathogens

Silencing of end-joining repair for efficient site-specific gene insertion after TALEN/CRISPR mutagenesis inAedes aegypti

(2015) Sanjay Basu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Highly efficient Cas9-mediated gene drive for population modification of the malaria vector mosquitoAnopheles stephensi

(2015) Valentino M. Gantz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Role of RNA Interference (RNAi) in Arbovirus-Vector Interactions

(2015) Carol Blair et al.   Viruses-Basel

Genome Engineering with CRISPR-Cas9 in the Mosquito Aedes aegypti

(2015) Kathryn E. Kistler et al.   Cell Reports

Genetic technologies for disease vectors

(2015) Frank Criscione et al.   Current Opinion in Insect Science

Heritable CRISPR/Cas9-Mediated Genome Editing in the Yellow Fever Mosquito, Aedes aegypti

(2015) Shengzhang Dong et al.   PLoS One

Suppression of the Arboviruses Dengue and Chikungunya Using a Dual-Acting Group-I Intron Coupled with Conditional Expression of the Bax C-Terminal Domain

(2015) James R. Carter et al.   PLoS One

History of domestication and spread of Aedes aegypti - A Review

(2014) Jeffrey R Powell et al.   MEMORIAS DO INSTITUTO OSWALDO CRUZ

Identification of germline transcriptional regulatory elements in Aedes aegypti

(2014) Omar S. Akbari et al.   Scientific Reports

Fitness Impact and Stability of a Transgene Conferring Resistance to Dengue-2 Virus following Introgression into a Genetically Diverse Aedes aegypti Strain

(2014) Alexander W. E. Franz et al.   PLoS Neglected Tropical Diseases

Transinfected Wolbachia have minimal effects on male reproductive success in Aedes aegypti

(2013) Andrew P Turley et al.   Parasites & Vectors

The Potent and Broadly Neutralizing Human Dengue Virus-Specific Monoclonal Antibody 1C19 Reveals a Unique Cross-Reactive Epitope on the bc Loop of Domain II of the Envelope Protein

(2013) S. A. Smith et al.   mBio

Germline excision of transgenes in Aedes aegypti by homing endonucleases

(2013) Azadeh Aryan et al.   Scientific Reports

Field Cage Studies and Progressive Evaluation of Genetically-Engineered Mosquitoes

(2013) Luca Facchinelli et al.   PLoS Neglected Tropical Diseases

Specificity of resistance to dengue virus isolates is associated with genotypes of the mosquito antiviral gene Dicer-2

(2012) L. Lambrechts et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

(2012) M. Jinek et al.   SCIENCE

Flight Performance and Teneral Energy Reserves of Two Genetically-Modified and One Wild-Type Strain of the Yellow Fever Mosquito Aedes aegypti

(2012) Irka Bargielowski et al.   VECTOR-BORNE AND ZOONOTIC DISEASES

A synthetic homing endonuclease-based gene drive system in the human malaria mosquito

(2011) Nikolai Windbichler et al.   NATURE

The wMel Wolbachia strain blocks dengue and invades caged Aedes aegypti populations

(2011) T. Walker et al.   NATURE

Field performance of engineered male mosquitoes

(2011) Angela F Harris et al.   NATURE BIOTECHNOLOGY

Comparison of Life History Characteristics of the Genetically Modified OX513A Line and a Wild Type Strain of Aedes aegypti

(2011) Irka Bargielowski et al.   PLoS One

Selfish genetic elements, genetic conflict, and evolutionary innovation

(2011) J. H. Werren   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MEDEA SELFISH GENETIC ELEMENTS AS TOOLS FOR ALTERING TRAITS OF WILD POPULATIONS: A THEORETICAL ANALYSIS

(2010) Catherine M. Ward et al.   EVOLUTION

Targeting DNA Double-Strand Breaks with TAL Effector Nucleases

(2010) M. Christian et al.   GENETICS

Transgene-mediated suppression of dengue viruses in the salivary glands of the yellow fever mosquito,Aedes aegypti

(2010) G. Mathur et al.   INSECT MOLECULAR BIOLOGY

Reframing Critical Needs in Vector Biology and Management of Vector-Borne Disease

(2010) Shirley Luckhart et al.   PLoS Neglected Tropical Diseases

A Wolbachia Symbiont in Aedes aegypti Limits Infection with Dengue, Chikungunya, and Plasmodium

(2009) Luciano A. Moreira et al.   CELL

Homing endonucleases catalyze double-stranded DNA breaks and somatic transgene excision inAedes aegypti

(2009) B. E. Traver et al.   INSECT MOLECULAR BIOLOGY

An evolutionary conserved function of the JAK-STAT pathway in anti-dengue defense

(2009) J. A. Souza-Neto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stable Introduction of a Life-Shortening Wolbachia Infection into the Mosquito Aedes aegypti

(2009) C. J. McMeniman et al.   SCIENCE

Effective suppression of Dengue fever virus in mosquito cell cultures using retroviral transduction of hammerhead ribozymes targeting the viral genome

(2009) Pruksa Nawtaisong et al.   Virology Journal

Skeeter Buster: A Stochastic, Spatially Explicit Modeling Tool for Studying Aedes aegypti Population Replacement and Population Suppression Strategies

(2009) Krisztian Magori et al.   PLoS Neglected Tropical Diseases

Host Adaptation of a Wolbachia Strain after Long-Term Serial Passage in Mosquito Cell Lines

(2008) C. J. McMeniman et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

BROADENING THE APPLICATION OF EVOLUTIONARILY BASED GENETIC PEST MANAGEMENT

(2008) Fred Gould   EVOLUTION

The Population Genetics of Using Homing Endonuclease Genes in Vector and Pest Management

(2008) A. Deredec et al.   GENETICS