Senolytics (DQ) Mitigates Radiation Ulcers by Removing Senescent Cells

Prevention and Treatment of Chemotherapy and Radiotherapy Induced Oral Mucositis

(2019) Goda Daugėlaitė et al.   Medicina-Lithuania

Cordycepin prevents radiation ulcer by inhibiting cell senescence via NRF2 and AMPK in rodents

(2019) Ziwen Wang et al.   Nature Communications

Mechanisms and functions of cellular senescence

(2018) Nicolás Herranz et al.   JOURNAL OF CLINICAL INVESTIGATION

Oral mucosa tissue gene expression profiling before, during, and after radiation therapy for tonsil squamous cell carcinoma

(2018) Mette Marcussen et al.   PLoS One

Abstract 465: Regulation of HMGB1 release protects chemoradiotherapy-associated mucositis

(2018) Keon-Il Im et al.   CANCER RESEARCH

Effect of modulation of epithelial‑mesenchymal transition regulators Snail1 and Snail2 on cancer cell radiosensitivity by targeting of the cell cycle, cell apoptosis and cell migration/invasion (Review)

(2018) Ganiou Assani et al.   Oncology Letters

Management of elderly patients with locoregionally confined head and neck cancer

(2017) Sandro V Porceddu et al.   LANCET ONCOLOGY

Cytoplasmic chromatin triggers inflammation in senescence and cancer

(2017) Zhixun Dou et al.   NATURE

Targeting cellular senescence prevents age-related bone loss in mice

(2017) Joshua N Farr et al.   NATURE MEDICINE

Increase in the radioresistance of normal skin fibroblasts but not tumor cells by mechanical injury

(2017) Zelin Chen et al.   Cell Death & Disease

Cellular senescence mediates fibrotic pulmonary disease

(2017) Marissa J. Schafer et al.   Nature Communications

Cellular senescence drives age-dependent hepatic steatosis

(2017) Mikolaj Ogrodnik et al.   Nature Communications

Defining stem cell dynamics and migration during wound healing in mouse skin epidermis

(2017) Mariaceleste Aragona et al.   Nature Communications

Development of Therapeutic Small-Molecule Fluorophore for Cell Transplantation

(2016) Xin Wang et al.   ADVANCED FUNCTIONAL MATERIALS

Cellular Senescence Promotes Adverse Effects of Chemotherapy and Cancer Relapse

(2016) Marco Demaria et al.   Cancer Discovery

Primary breast cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

(2015) E. Senkus et al.   ANNALS OF ONCOLOGY

Radiation induced oral mucositis: a review of current literature on prevention and management

(2015) Supriya Mallick et al.   EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY

Senescent cells communicate via intercellular protein transfer

(2015) Anat Biran et al.   GENES & DEVELOPMENT

The Essence of Aging

(2015) Jan Vijg et al.   GERONTOLOGY

MTOR regulates the pro-tumorigenic senescence-associated secretory phenotype by promoting IL1A translation

(2015) Remi-Martin Laberge et al.   NATURE CELL BIOLOGY

Opportunities and challenges of radiotherapy for treating cancer

(2015) Dörthe Schaue et al.   Nature Reviews Clinical Oncology

Molecular Pathways: Molecular Basis for Sensitivity and Resistance to JAK Kinase Inhibitors

(2014) S. C. Meyer et al.   CLINICAL CANCER RESEARCH

How we manage JAK inhibition in allogeneic transplantation for myelofibrosis

(2014) Tarah J. Ballinger et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

The role of senescent cells in ageing

(2014) Jan M. van Deursen   NATURE

Senescence Is a Developmental Mechanism that Contributes to Embryonic Growth and Patterning

(2013) Mekayla Storer et al.   CELL

Interconnections between apoptotic, autophagic and necrotic pathways: implications for cancer therapy development

(2013) Mayur V. Jain et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Preventive and therapeutic effects of Smad7 on radiation-induced oral mucositis

(2013) Gangwen Han et al.   NATURE MEDICINE

Systematic review of antimicrobials, mucosal coating agents, anesthetics, and analgesics for the management of oral mucositis in cancer patients

(2013) Deborah P. Saunders et al.   SUPPORTIVE CARE IN CANCER

Aging, Cellular Senescence, and Cancer

(2012) Judith Campisi   Annual Review of Physiology

mTOR Inhibition Prevents Epithelial Stem Cell Senescence and Protects from Radiation-Induced Mucositis

(2012) Ramiro Iglesias-Bartolome et al.   Cell Stem Cell

Accelerated aging phenotype in mice with conditional deficiency for mitochondrial superoxide dismutase in the connective tissue

(2011) Nicolai Treiber et al.   AGING CELL

The Senescence-Associated Secretory Phenotype: The Dark Side of Tumor Suppression

(2010) Jean-Philippe Coppé et al.   Annual Review of Pathology-Mechanisms of Disease

Feedback between p21 and reactive oxygen production is necessary for cell senescence

(2010) João F Passos et al.   Molecular Systems Biology

Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion

(2009) Francis Rodier et al.   NATURE CELL BIOLOGY

Accelerated senescence: An emerging role in tumor cell response to chemotherapy and radiation

(2008) David A. Gewirtz et al.   BIOCHEMICAL PHARMACOLOGY

Chemokine Signaling via the CXCR2 Receptor Reinforces Senescence

(2008) Juan C. Acosta et al.   CELL

Efficacy of Superoxide Dismutase Mimetic M40403 in Attenuating Radiation-Induced Oral Mucositis in Hamsters

(2008) C. K. Murphy et al.   CLINICAL CANCER RESEARCH

Senescence-Associated Secretory Phenotypes Reveal Cell-Nonautonomous Functions of Oncogenic RAS and the p53 Tumor Suppressor

(2008) Jean-Philippe Coppé et al.   PLOS BIOLOGY