Impact of Radiochemotherapy on Immune Cell Subtypes in High-Grade Glioma Patients

Temozolomide for immunomodulation in the treatment of glioblastoma

(2018) Aida Karachi et al.   NEURO-ONCOLOGY

Concepts for Immunotherapies in Gliomas

(2018) Michael Platten et al.   SEMINARS IN NEUROLOGY

Temozolomide lymphodepletion enhances CAR abundance and correlates with antitumor efficacy against established glioblastoma

(2018) Carter M. Suryadevara et al.   OncoImmunology

Sequestration of T cells in bone marrow in the setting of glioblastoma and other intracranial tumors

(2018) Pakawat Chongsathidkiet et al.   NATURE MEDICINE

Immunotherapy for Brain Tumors

(2018) Lan B. Hoang-Minh et al.   CURRENT TREATMENT OPTIONS IN ONCOLOGY

Immune Checkpoints and Innovative Therapies in Glioblastoma

(2018) Massimo Romani et al.   Frontiers in Oncology

Effect of Tumor-Treating Fields Plus Maintenance Temozolomide vs Maintenance Temozolomide Alone on Survival in Patients With Glioblastoma

(2017) Roger Stupp et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Serial changes in lymphocyte subsets in patients with newly diagnosed high grade astrocytomas treated with standard radiation and temozolomide

(2017) Jian L. Campian et al.   JOURNAL OF NEURO-ONCOLOGY

Vaccine-based immunotherapeutic approaches to gliomas and beyond

(2017) Michael Weller et al.   Nature Reviews Neurology

Corticosteroids compromise survival in glioblastoma

(2016) Kenneth L. Pitter et al.   BRAIN

A Cancer Research UK First Time in Human Phase I Trial of IMA950 (Novel Multipeptide Therapeutic Vaccine) in Patients with Newly Diagnosed Glioblastoma

(2016) R. Rampling et al.   CLINICAL CANCER RESEARCH

Immunotherapy of Malignant Tumors in the Brain: How Different from Other Sites?

(2016) Valérie Dutoit et al.   Frontiers in Oncology

Immune-priming of the Tumor Microenvironment by Radiotherapy

(2015) Vafa Shahabi et al.   AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS

The abscopal effect of local radiotherapy: using immunotherapy to make a rare event clinically relevant

(2015) Kobe Reynders et al.   CANCER TREATMENT REVIEWS

Survival in Patients With Severe Lymphopenia Following Treatment With Radiation and Chemotherapy for Newly Diagnosed Solid Tumors

(2015) Stuart A. Grossman et al.   Journal of the National Comprehensive Cancer Network

Cilengitide combined with standard treatment for patients with newly diagnosed glioblastoma with methylated MGMT promoter (CENTRIC EORTC 26071-22072 study): a multicentre, randomised, open-label, phase 3 trial

(2014) Roger Stupp et al.   LANCET ONCOLOGY

Leveraging chemotherapy-induced lymphopenia to potentiate cancer immunotherapy

(2014) Luis Sanchez-Perez et al.   OncoImmunology

Sustained CD4+T cell-driven lymphopenia without a compensatory IL-7/IL-15 response among high-grade glioma patients treated with radiation and temozolomide

(2014) Susannah Ellsworth et al.   OncoImmunology

The Etiology of Treatment-related Lymphopenia in Patients with Malignant Gliomas: Modeling Radiation Dose to Circulating Lymphocytes Explains Clinical Observations and Suggests Methods of Modifying the Impact of Radiation on Immune Cells

(2013) Susannah Yovino et al.   CANCER INVESTIGATION

Profound Impairment of Adaptive Immune Responses by Alkylating Chemotherapy

(2013) A. J. Litterman et al.   JOURNAL OF IMMUNOLOGY

The association of pre-treatment neutrophil to lymphocyte ratio with overall survival in patients with glioblastoma multiforme

(2013) R. M. Bambury et al.   JOURNAL OF NEURO-ONCOLOGY

Myeloablative Temozolomide Enhances CD8+ T-Cell Responses to Vaccine and Is Required for Efficacy against Brain Tumors in Mice

(2013) Luis A. Sanchez-Perez et al.   PLoS One

Multipeptide immune response to cancer vaccine IMA901 after single-dose cyclophosphamide associates with longer patient survival

(2012) Steffen Walter et al.   NATURE MEDICINE

A Prospective Study of the Factors Shaping Antibody Responses to the AS03-Adjuvanted Influenza A/H1N1 Vaccine in Cancer Outpatients

(2012) A. F. Hottinger et al.   ONCOLOGIST

Monoclonal antibody blockade of IL-2 receptor   during lymphopenia selectively depletes regulatory T cells in mice and humans

(2011) D. A. Mitchell et al.   BLOOD

Immunosuppression in Patients with High-Grade Gliomas Treated with Radiation and Temozolomide

(2011) Stuart A. Grossman et al.   CLINICAL CANCER RESEARCH

Immune modulation effects of concomitant temozolomide and radiation therapy on peripheral blood mononuclear cells in patients with glioblastoma multiforme

(2011) C. E. Fadul et al.   NEURO-ONCOLOGY

Mechanism of synergistic effect of chemotherapy and immunotherapy of cancer

(2010) Rupal Ramakrishnan et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Greater chemotherapy-induced lymphopenia enhances tumor-specific immune responses that eliminate EGFRvIII-expressing tumor cells in patients with glioblastoma

(2010) J. H. Sampson et al.   NEURO-ONCOLOGY

Treg depletion with a low-dose metronomic temozolomide regimen in a rat glioma model

(2009) Claire Banissi et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Immunological Factors Relating to the Antitumor Effect of Temozolomide Chemoimmunotherapy in a Murine Glioma Model

(2009) T.-G. Kim et al.   Clinical and Vaccine Immunology

Functional Delineation and Differentiation Dynamics of Human CD4+ T Cells Expressing the FoxP3 Transcription Factor

(2009) Makoto Miyara et al.   IMMUNITY

Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial

(2009) Roger Stupp et al.   LANCET ONCOLOGY

IDH1andIDH2Mutations in Gliomas

(2009) Hai Yan et al.   NEW ENGLAND JOURNAL OF MEDICINE