Design and Synthesis of Arf1-Targeting γ-Dipeptides as Potential Agents against Head and Neck Squamous Cell Carcinoma

Cancer statistics, 2019

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Drugging the Small GTPase Pathways in Cancer Treatment: Promises and Challenges

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Histone deacetylase inhibitors suppress aggressiveness of head and neck squamous cell carcinoma via histone acetylation-independent blockade of the EGFR-Arf1 axis

(2019) Leilei He et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Nivolumab in Patients with Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck: Efficacy and Safety in CheckMate 141 by Prior Cetuximab Use

(2019) Robert L. Ferris et al.   CLINICAL CANCER RESEARCH

COTI-2, a novel thiosemicarbazone derivative, exhibits antitumor activity in HNSCC through p53-dependent and -independent mechanisms

(2019) Antje Lindemann et al.   CLINICAL CANCER RESEARCH

Clinical update on head and neck cancer: molecular biology and ongoing challenges

(2019) Elham Alsahafi et al.   Cell Death & Disease

Simultaneously inactivating Src and AKT by saracatinib/capivasertib co-delivery nanoparticles to improve the efficacy of anti-Src therapy in head and neck squamous cell carcinoma

(2019) Liwei Lang et al.   Journal of Hematology & Oncology

Can Heterocyclic γ-Peptides Provide Polyfunctional Platforms for Synthetic Glycocluster Construction?

(2018) Matthieu Simon et al.   CHEMISTRY-A EUROPEAN JOURNAL

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

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High PD-L1 expression in the tumour cells did not correlate with poor prognosis of patients suffering for oral squamous cells carcinoma: A meta-analysis of the literature

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Combined targeting of Arf1 and Ras potentiates anticancer activity for prostate cancer therapeutics

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Targeting the Golgi apparatus to overcome acquired resistance of non-small cell lung cancer cells to EGFR tyrosine kinase inhibitors

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Safety and clinical activity of pembrolizumab for treatment of recurrent or metastatic squamous cell carcinoma of the head and neck (KEYNOTE-012): an open-label, multicentre, phase 1b trial

(2016) Tanguy Y Seiwert et al.   LANCET ONCOLOGY

Head and Neck Squamous Cell Carcinoma: Update on Epidemiology, Diagnosis, and Treatment

(2016) Shanthi Marur et al.   MAYO CLINIC PROCEEDINGS

FT-IR and NMR structural markers for thiazole-based γ-peptide foldamers

(2016) C. Bonnel et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Suppression of breast cancer metastasis through the inactivation of ADP-ribosylation factor 1

(2016) Xiayang Xie et al.   Oncotarget

ARF1 promotes prostate tumorigenesis via targeting oncogenic MAPK signaling

(2016) Jason E. Davis et al.   Oncotarget

The small GTPase ADP-Ribosylation Factor 1 mediates the sensitivity of triple negative breast cancer cells to EGFR tyrosine kinase inhibitors

(2015) Eric Haines et al.   CANCER BIOLOGY & THERAPY

Cross-Claisen Condensation ofN-Fmoc-Amino Acids - A Short Route to Heterocyclic γ-Amino Acids

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The Adaptor Proteins p66Shc and Grb2 Regulate the Activation of the GTPases ARF1 and ARF6 in Invasive Breast Cancer Cells

(2014) Eric Haines et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cytohesins/ARNO: The Function in Colorectal Cancer Cells

(2014) Tao Pan et al.   PLoS One

Epidemiologic Trends in Head and Neck Cancer and Aids in Diagnosis

(2014) Nadarajah Vigneswaran et al.   Oral and Maxillofacial Surgery Clinics of North America

Helical Oligomers of Thiazole-Based γ-Amino Acids: Synthesis and Structural Studies

(2013) Loïc Mathieu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Fragment-Based Identification of a Locus in the Sec7 Domain of Arno for the Design of Protein–Protein Interaction Inhibitors

(2013) Jad Rouhana et al.   JOURNAL OF MEDICINAL CHEMISTRY

ARF1 regulates the Rho/MLC pathway to control EGF-dependent breast cancer cell invasion

(2013) Sabrina Schlienger et al.   MOLECULAR BIOLOGY OF THE CELL

Kinetics of Interaction between ADP-ribosylation Factor-1 (Arf1) and the Sec7 Domain of Arno Guanine Nucleotide Exchange Factor, Modulation by Allosteric Factors, and the Uncompetitive Inhibitor Brefeldin A

(2012) Jad Rouhana et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

AMF-26, a Novel Inhibitor of the Golgi System, Targeting ADP-ribosylation Factor 1 (Arf1) with Potential for Cancer Therapy

(2011) Yoshimi Ohashi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ARF family G proteins and their regulators: roles in membrane transport, development and disease

(2011) Julie G. Donaldson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

ARF1 controls proliferation of breast cancer cells by regulating the retinoblastoma protein

(2011) P-L Boulay et al.   ONCOGENE

The Mutational Landscape of Head and Neck Squamous Cell Carcinoma

(2011) N. Stransky et al.   SCIENCE

ADP-ribosylation Factor 1 Controls the Activation of the Phosphatidylinositol 3-Kinase Pathway to Regulate Epidermal Growth Factor-dependent Growth and Migration of Breast Cancer Cells

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