The amyloid-β degradation intermediate Aβ34 is pericyte-associated and reduced in brain capillaries of patients with Alzheimer’s disease

Vascular dysfunction—The disregarded partner of Alzheimer's disease

(2019) Melanie D. Sweeney et al.   Alzheimers & Dementia

Beta-amyloid pathology in human brain microvessel extracts from the parietal cortex: relation with cerebral amyloid angiopathy and Alzheimer’s disease

(2019) Philippe Bourassa et al.   ACTA NEUROPATHOLOGICA

Aβ34 is a BACE1-derived degradation intermediate associated with amyloid clearance and Alzheimer’s disease progression

(2019) Filip Liebsch et al.   Nature Communications

Aβ truncated species: Implications for brain clearance mechanisms and amyloid plaque deposition

(2018) Erwin Cabrera et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Pericyte implantation in the brain enhances cerebral blood flow and reduces amyloid-β pathology in amyloid model mice

(2018) Masaya Tachibana et al.   EXPERIMENTAL NEUROLOGY

A Simple and Reproducible Method to Prepare Membrane Samples from Freshly Isolated Rat Brain Microvessels

(2018) Hrvoje Brzica et al.   Jove-Journal of Visualized Experiments

Are N- and C-terminally Truncated Aβ species key pathological triggers in Alzheimer’s disease?

(2018) Julie Dunys et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Blood-brain barrier-associated pericytes internalize and clear aggregated amyloid-β42 by LRP1-dependent apolipoprotein E isoform-specific mechanism

(2018) Qingyi Ma et al.   Molecular Neurodegeneration

Arterial Pulsations cannot Drive Intramural Periarterial Drainage: Significance for Aβ Drainage

(2017) Alexandra K. Diem et al.   Frontiers in Neuroscience

Distinct deposition of amyloid-β species in brains with Alzheimer’s disease pathology visualized with MALDI imaging mass spectrometry

(2017) Nobuto Kakuda et al.   Acta Neuropathologica Communications

Role of the N-terminus for the stability of an amyloid-β fibril with three-fold symmetry

(2017) Christian A. Söldner et al.   PLoS One

Endocytic uptake of monomeric amyloid-β peptides is clathrin- and dynamin-independent and results in selective accumulation of Aβ(1–42) compared to Aβ(1–40)

(2017) Emelie Wesén et al.   Scientific Reports

Diversity of Amyloid-beta Proteoforms in the Alzheimer’s Disease Brain

(2017) Norelle C. Wildburger et al.   Scientific Reports

The amyloid hypothesis of Alzheimer's disease at 25 years

(2016) Dennis J Selkoe et al.   EMBO Molecular Medicine

Generation of aggregation prone N-terminally truncated amyloid β peptides by meprin β depends on the sequence specificity at the cleavage site

(2016) Caroline Schönherr et al.   Molecular Neurodegeneration

Complex interplay between brain function and structure during cerebral amyloidosis in APP transgenic mouse strains revealed by multi-parametric MRI comparison

(2016) Joanes Grandjean et al.   NEUROIMAGE

Deposition of C-terminally truncated Aβ species Aβ37 and Aβ39 in Alzheimer’s disease and transgenic mouse models

(2016) Jochim Reinert et al.   Acta Neuropathologica Communications

Sequential Amyloid-β Degradation by the Matrix Metalloproteases MMP-2 and MMP-9

(2015) Mar Hernandez-Guillamon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

BACE-1 is expressed in the blood–brain barrier endothelium and is upregulated in a murine model of Alzheimer’s disease

(2015) Kavi Devraj et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Accelerated pericyte degeneration and blood–brain barrier breakdown in apolipoprotein E4 carriers with Alzheimer’s disease

(2015) Matthew R Halliday et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Control tissue in brain banking: the importance of thorough neuropathological assessment

(2015) M. Nolan et al.   JOURNAL OF NEURAL TRANSMISSION

Purification of Mouse Brain Vessels

(2015) Anne-Cécile Boulay et al.   Jove-Journal of Visualized Experiments

Neuropathology and biochemistry of Aβ and its aggregates in Alzheimer’s disease

(2014) Dietmar Rudolf Thal et al.   ACTA NEUROPATHOLOGICA

Study on Aβ34 biology and detection in transgenic mice brains

(2014) Céline Caillava et al.   NEUROBIOLOGY OF AGING

Occludin deficiency with BACE1 elevation in cerebral amyloid angiopathy

(2014) X. Cheng et al.   NEUROLOGY

β-site amyloid precursor protein-cleaving enzyme 1(BACE1) inhibitor treatment induces Aβ5-X peptides through alternative amyloid precursor protein cleavage

(2014) Erik Portelius et al.   Alzheimers Research & Therapy

Tau-aggregation inhibitor therapy for Alzheimer's disease

(2013) Claude M. Wischik et al.   BIOCHEMICAL PHARMACOLOGY

Characterization of Intermediate Steps in Amyloid Beta (Aβ) Production under Near-native Conditions

(2013) Fredrik Olsson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Reliable Way to Detect Endogenous Murine β-Amyloid

(2013) Andrew F. Teich et al.   PLoS One

Pericyte loss influences Alzheimer-like neurodegeneration in mice

(2013) Abhay P. Sagare et al.   Nature Communications

National Institute on Aging–Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease

(2012) Bradley T. Hyman et al.   Alzheimers & Dementia

Deficiency in Mural Vascular Cells Coincides with Blood-Brain Barrier Disruption in Alzheimer's Disease

(2012) Jesse D. Sengillo et al.   BRAIN PATHOLOGY

Brain microvascular pericytes in health and disease

(2011) Turgay Dalkara et al.   ACTA NEUROPATHOLOGICA

Perivascular drainage of solutes is impaired in the ageing mouse brain and in the presence of cerebral amyloid angiopathy

(2011) Cheryl A. Hawkes et al.   ACTA NEUROPATHOLOGICA

National Institute on Aging–Alzheimer’s Association guidelines for the neuropathologic assessment of Alzheimer’s disease: a practical approach

(2011) Thomas J. Montine et al.   ACTA NEUROPATHOLOGICA

Pericytes: Developmental, Physiological, and Pathological Perspectives, Problems, and Promises

(2011) Annika Armulik et al.   DEVELOPMENTAL CELL

APP processing in Alzheimer's disease

(2011) Yun-wu Zhang et al.   Molecular Brain

Mass spectrometric characterization of brain amyloid beta isoform signatures in familial and sporadic Alzheimer’s disease

(2010) Erik Portelius et al.   ACTA NEUROPATHOLOGICA

Pericytes regulate the blood–brain barrier

(2010) Annika Armulik et al.   NATURE

Pericytes Control Key Neurovascular Functions and Neuronal Phenotype in the Adult Brain and during Brain Aging

(2010) Robert D. Bell et al.   NEURON

Decreased Clearance of CNS  -Amyloid in Alzheimer's Disease

(2010) K. G. Mawuenyega et al.   SCIENCE

CNS pericytes: Concepts, misconceptions, and a way out

(2009) Martin Krueger et al.   GLIA

Aminopeptidase A contributes to the N-terminal truncation of amyloid β-peptide

(2009) Jean Sevalle et al.   JOURNAL OF NEUROCHEMISTRY

 -Secretase: Successive Tripeptide and Tetrapeptide Release from the Transmembrane Domain of  -Carboxyl Terminal Fragment

(2009) M. Takami et al.   JOURNAL OF NEUROSCIENCE

An Overview of APP Processing Enzymes and Products

(2009) Vivian W. Chow et al.   NEUROMOLECULAR MEDICINE

Cerebral amyloid angiopathy in the aetiology and immunotherapy of Alzheimer disease

(2009) Roy O Weller et al.   Alzheimers Research & Therapy