Chromatin accessibility analysis reveals regulatory dynamics of developing human retina and hiPSC-derived retinal organoids

Single-Cell RNA-Seq Analysis of Retinal Development Identifies NFI Factors as Regulating Mitotic Exit and Late-Born Cell Specification

(2019) Brian S. Clark et al.   NEURON

Generation, transcriptome profiling, and functional validation of cone-rich human retinal organoids

(2019) Sangbae Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gene Correction Reverses Ciliopathy and Photoreceptor Loss in iPSC-Derived Retinal Organoids from Retinitis Pigmentosa Patients

(2018) Wen-Li Deng et al.   Stem Cell Reports

Thyroid hormone signaling specifies cone subtypes in human retinal organoids

(2018) Kiara C. Eldred et al.   SCIENCE

The chromatin accessibility landscape of primary human cancers

(2018) M. Ryan Corces et al.   SCIENCE

RUNX-mediated growth arrest and senescence are attenuated by diverse mechanisms in cells expressing RUNX1 fusion oncoproteins

(2017) Gail Anderson et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

The Dynamic Epigenetic Landscape of the Retina During Development, Reprogramming, and Tumorigenesis

(2017) Issam Aldiri et al.   NEURON

Bivariate Genomic Footprinting Detects Changes in Transcription Factor Activity

(2017) Songjoon Baek et al.   Cell Reports

Activin Signals through SMAD2/3 to Increase Photoreceptor Precursor Yield during Embryonic Stem Cell Differentiation

(2017) Amy Q. Lu et al.   Stem Cell Reports

NFIB Mediates BRN2 Driven Melanoma Cell Migration and Invasion Through Regulation of EZH2 and MITF

(2017) Mitchell E. Fane et al.   EBioMedicine

Lhx2 Is an Essential Factor for Retinal Gliogenesis and Notch Signaling

(2016) Jimmy de Melo et al.   JOURNAL OF NEUROSCIENCE

Distinct features of H3K4me3 and H3K27me3 chromatin domains in pre-implantation embryos

(2016) Xiaoyu Liu et al.   NATURE

Epigenomic landscapes of retinal rods and cones

(2016) Alisa Mo et al.   eLife

Retinal Organoids from Pluripotent Stem Cells Efficiently Recapitulate Retinogenesis

(2016) Manuela Völkner et al.   Stem Cell Reports

Leukemia-Associated Cohesin Mutants Dominantly Enforce Stem Cell Programs and Impair Human Hematopoietic Progenitor Differentiation

(2015) Claire Mazumdar et al.   Cell Stem Cell

Individuality and Variation of Personal Regulomes in Primary Human T Cells

(2015) Kun Qu et al.   Cell Systems

Stage-dependent requirement of neuroretinal Pax6 for lens and retina development

(2014) L. Klimova et al.   DEVELOPMENT

OTX2 loss causes rod differentiation defect in CRX-associated congenital blindness

(2014) Jerome E. Roger et al.   JOURNAL OF CLINICAL INVESTIGATION

Intrinsically different retinal progenitor cells produce specific types of progeny

(2014) Connie Cepko   NATURE REVIEWS NEUROSCIENCE

Generation of three-dimensional retinal tissue with functional photoreceptors from human iPSCs

(2014) Xiufeng Zhong et al.   Nature Communications

A double take on bivalent promoters

(2013) P. Voigt et al.   GENES & DEVELOPMENT

Nuclear factor one B regulates neural stem cell differentiation and axonal projection of corticofugal neurons

(2013) Jennifer Betancourt et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position

(2013) Jason D Buenrostro et al.   NATURE METHODS

Low Incidence of DNA Sequence Variation in Human Induced Pluripotent Stem Cells Generated by Nonintegrating Plasmid Expression

(2012) Linzhao Cheng et al.   Cell Stem Cell

ChromHMM: automating chromatin-state discovery and characterization

(2012) Jason Ernst et al.   NATURE METHODS

Vsx2 Controls Eye Organogenesis and Retinal Progenitor Identity Via Homeodomain and Non-Homeodomain Residues Required for High Affinity DNA Binding

(2012) Changjiang Zou et al.   PLoS Genetics

Melanopsin signalling in mammalian iris and retina

(2011) T. Xue et al.   NATURE

GREAT improves functional interpretation of cis-regulatory regions

(2010) Cory Y McLean et al.   NATURE BIOTECHNOLOGY

Differential CRX and OTX2 expression in human retina and retinoblastoma

(2009) Darryl D. Glubrecht et al.   JOURNAL OF NEUROCHEMISTRY

Matching incomplete time series with dynamic time warping: an algorithm and an application to post-stroke rehabilitation

(2008) Paolo Tormene et al.   ARTIFICIAL INTELLIGENCE IN MEDICINE

Rod differentiation factor NRL activates the expression of nuclear receptor NR2E3 to suppress the development of cone photoreceptors

(2008) Edwin C.T. Oh et al.   BRAIN RESEARCH

Gene-regulation logic in retinal ganglion cell development: Isl1 defines a critical branch distinct from but overlapping with Pou4f2

(2008) X. Mu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA