Crystalline Silica Impairs Efferocytosis Abilities of Human and Mouse Macrophages: Implication for Silica-Associated Systemic Sclerosis

5-Aryl-1,3,4-oxadiazol-2-ylthioalkanoic Acids: A Highly Potent New Class of Inhibitors of Rho/Myocardin-Related Transcription Factor (MRTF)/Serum Response Factor (SRF)-Mediated Gene Transcription as Potential Antifibrotic Agents for Scleroderma

(2019) Dylan J. Kahl et al.   JOURNAL OF MEDICINAL CHEMISTRY

The world is failing on silicosis

(2019) The Lancet Respiratory Medicine   Lancet Respiratory Medicine

Silica Particles Mediate Phenotypic and Functional Alteration of Dendritic Cells and Induce Th2 Cell Polarization

(2019) Suna Liu et al.   Frontiers in Immunology

The contribution of macrophages to systemic lupus erythematosus

(2019) Chunyan Ma et al.   CLINICAL IMMUNOLOGY

Macrophage-targeting Fasudil treatment protects liver from the ischemia/reperfusion injury by promoting M2 macrophage polarization

(2018) Yingli Xie et al.   BIOSCIENCE REPORTS

High prevalence of occupational exposure to solvents or silica in male systemic sclerosis patients: a Belgian cohort analysis

(2018) Evelien De Decker et al.   CLINICAL RHEUMATOLOGY

High serum levels of silica nanoparticles in systemic sclerosis patients with occupational exposure: possible pathogenetic role in disease phenotypes

(2018) Clodoveo Ferri et al.   SEMINARS IN ARTHRITIS AND RHEUMATISM

Silicosis and Silica-Induced Autoimmunity in the Diversity Outbred Mouse

(2018) Jessica M. Mayeux et al.   Frontiers in Immunology

The Role of Efferocytosis in Autoimmune Diseases

(2018) Fereshte Abdolmaleki et al.   Frontiers in Immunology

Efferocytosis capacities of blood monocyte‐derived macrophages in systemic sclerosis

(2018) Alice Ballerie et al.   IMMUNOLOGY AND CELL BIOLOGY

Systemic sclerosis

(2017) Christopher P Denton et al.   LANCET

SR-B1 Is a Silica Receptor that Mediates Canonical Inflammasome Activation

(2017) Misato Tsugita et al.   Cell Reports

Rac2 is required for alternative macrophage activation and bleomycin induced pulmonary fibrosis; a macrophage autonomous phenotype

(2017) Shweta Joshi et al.   PLoS One

ROCK inhibition impedes macrophage polarity and functions

(2016) Yianzhu Liu et al.   CELLULAR IMMUNOLOGY

RhoA/Rho-kinase activation promotes lung fibrosis in an animal model of systemic sclerosis

(2016) Yihua Bei et al.   EXPERIMENTAL LUNG RESEARCH

Silica, Silicosis, and Autoimmunity

(2016) Kenneth Michael Pollard   Frontiers in Immunology

Prospective Risk of Rheumatologic Disease Associated with Occupational Exposure in a Cohort of Male Construction Workers

(2015) Paul D. Blanc et al.   AMERICAN JOURNAL OF MEDICINE

Mesenchymal stem cells promote CD206 expression and phagocytic activity of macrophages through IL-6 in systemic lupus erythematosus

(2015) Wei Deng et al.   CLINICAL IMMUNOLOGY

Apoptotic cell recognition receptors and scavenger receptors

(2015) Kristen K. Penberthy et al.   IMMUNOLOGICAL REVIEWS

PPARγ activation following apoptotic cell instillation promotes resolution of lung inflammation and fibrosis via regulation of efferocytosis and proresolving cytokines

(2015) Y-S Yoon et al.   Mucosal Immunology

Investigation of the association between Rho/Rho-kinase gene polymorphisms and systemic sclerosis

(2015) Yavuz Pehlivan et al.   RHEUMATOLOGY INTERNATIONAL

ROCK-Isoform-Specific Polarization of Macrophages Associated with Age-Related Macular Degeneration

(2015) Souska Zandi et al.   Cell Reports

Clearance of Apoptotic Bodies, NETs, and Biofilm DNA: Implications for Autoimmunity

(2014) Marko Radic   Frontiers in Immunology

2013 Classification Criteria for Systemic Sclerosis: An American College of Rheumatology/European League Against Rheumatism Collaborative Initiative

(2013) Frank van den Hoogen et al.   ARTHRITIS AND RHEUMATISM

Polarization profiles of human M-CSF-generated macrophages and comparison of M1-markers in classically activated macrophages from GM-CSF and M-CSF origin

(2013) Marie Jaguin et al.   CELLULAR IMMUNOLOGY

Targeting the Shift from M1 to M2 Macrophages in Experimental Autoimmune Encephalomyelitis Mice Treated with Fasudil

(2013) Chunyun Liu et al.   PLoS One

Modulation of macrophage phenotype by cell shape

(2013) F. Y. McWhorter et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epidemiology of environmental exposures and human autoimmune diseases: Findings from a National Institute of Environmental Health Sciences Expert Panel Workshop

(2012) Frederick W. Miller et al.   JOURNAL OF AUTOIMMUNITY

Silicosis

(2012) Chi Chiu Leung et al.   LANCET

Defective efferocytosis by alveolar macrophages in IPF patients

(2012) Konosuke Morimoto et al.   RESPIRATORY MEDICINE

Acute and Chronic Alcohol Exposure Impair the Phagocytosis of Apoptotic Cells and Enhance the Pulmonary Inflammatory Response

(2010) Darren M. Boé et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

The role of defective clearance of apoptotic cells in systemic autoimmunity

(2010) Luis E. Muñoz et al.   Nature Reviews Rheumatology

Cigarette Smoke Impairs Clearance of Apoptotic Cells through Oxidant-dependent Activation of RhoA

(2009) Tiffany R. Richens et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The Phagocytosis of Crystalline Silica Particles by Macrophages

(2008) Renée M. Gilberti et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Over-representation of construction-related occupations in male patients with systemic sclerosis

(2008) V Smith et al.   ANNALS OF THE RHEUMATIC DISEASES

Macrophage phagocytosis of apoptotic neutrophils is critically regulated by the opposing actions of pro-inflammatory and anti-inflammatory agents: key role for TNF-α

(2008) Sylwia Michlewska et al.   FASEB JOURNAL

Innate Immune Activation Through Nalp3 Inflammasome Sensing of Asbestos and Silica

(2008) C. Dostert et al.   SCIENCE