DDIAS promotes STAT3 activation by preventing STAT3 recruitment to PTPRM in lung cancer cells

DDIAS suppresses TRAIL-mediated apoptosis by inhibiting DISC formation and destabilizing caspase-8 in cancer cells

(2017) Joo-Young Im et al.   ONCOGENE

DNA damage induced apoptosis suppressor (DDIAS) is upregulated via ERK5/MEF2B signaling and promotes β-catenin-mediated invasion

(2016) Joo-Young Im et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

DNA damage-induced apoptosis suppressor (DDIAS), a novel target of NFATc1, is associated with cisplatin resistance in lung cancer

(2016) Joo-Young Im et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Receptor-type tyrosine-protein phosphatase   directly targets STAT3 activation for tumor suppression in nasal NK/T-cell lymphoma

(2015) Y.-W. Chen et al.   BLOOD

STAT3-Interacting Proteins as Modulators of Transcription Factor Function: Implications to Targeted Cancer Therapy

(2015) Jennifer E. Yeh et al.   ChemMedChem

CCR5 Blockade Suppresses Melanoma Development Through Inhibition of IL-6-Stat3 Pathway via Upregulation of SOCS3

(2015) Qiu Tang et al.   INFLAMMATION

NOXIN as a cofactor of DNA polymerase-primase complex could promote hepatocellular carcinoma

(2015) Zhuang-Zhuang Zhang et al.   INTERNATIONAL JOURNAL OF CANCER

Loss of PTPRM Associates with the Pathogenic Development of Colorectal Adenoma-Carcinoma Sequence

(2015) Putty-Reddy Sudhir et al.   Scientific Reports

GdX/UBL4A Specifically Stabilizes the TC45/STAT3 Association and Promotes Dephosphorylation of STAT3 to Repress Tumorigenesis

(2014) Yangmeng Wang et al.   MOLECULAR CELL

Peroxiredoxin-2 and STAT3 form a redox relay for H2O2 signaling

(2014) Mirko C Sobotta et al.   Nature Chemical Biology

Frequent mutation of receptor protein tyrosine phosphatases provides a mechanism for STAT3 hyperactivation in head and neck cancer

(2014) V. W. Y. Lui et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Role of STAT3 in Non-Small Cell Lung Cancer

(2014) Daijiro Harada et al.   Cancers

Human Noxin is an anti-apoptotic protein in response to DNA damage of A549 non-small cell lung carcinoma

(2013) Kyoung-Jae Won et al.   INTERNATIONAL JOURNAL OF CANCER

DNA methylation of membrane-bound tyrosine phosphatase genes in acute lymphoblastic leukaemia

(2013) W S Stevenson et al.   LEUKEMIA

Targeting interleukin-6 in inflammatory autoimmune diseases and cancers

(2013) Xin Yao et al.   PHARMACOLOGY & THERAPEUTICS

Protein tyrosine phosphatases - from housekeeping enzymes to master regulators of signal transduction

(2012) Nicholas K. Tonks   FEBS Journal

Circulating interleukin-6 level is a prognostic marker for survival in advanced nonsmall cell lung cancer patients treated with chemotherapy

(2012) Chin Hao Chang et al.   INTERNATIONAL JOURNAL OF CANCER

Orally bioavailable small-molecule inhibitor of transcription factor Stat3 regresses human breast and lung cancer xenografts

(2012) X. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ptpn11/Shp2 Acts as a Tumor Suppressor in Hepatocellular Carcinogenesis

(2011) Emilie A. Bard-Chapeau et al.   CANCER CELL

miR-221/222 overexpession in human glioblastoma increases invasiveness by targeting the protein phosphate PTPμ

(2011) C Quintavalle et al.   ONCOGENE

SOCS-3 antagonises the proliferative and migratory effects of fibroblast growth factor-2 in prostate cancer by inhibition of p44/p42 MAPK signalling

(2010) Martin Puhr et al.   ENDOCRINE-RELATED CANCER

TGF-  IL-6 axis mediates selective and adaptive mechanisms of resistance to molecular targeted therapy in lung cancer

(2010) Z. Yao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proteolytic Cleavage of Protein Tyrosine Phosphatase   Regulates Glioblastoma Cell Migration

(2009) A. M. Burgoyne et al.   CANCER RESEARCH

The tyrosine phosphatase PTPRD is a tumor suppressor that is frequently inactivated and mutated in glioblastoma and other human cancers

(2009) S. Veeriah et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA