The Impact of Oxidative Stress on Adipose Tissue Energy Balance

Oxidative Stress Inhibits Healthy Adipose Expansion Through Suppression of SREBF1-Mediated Lipogenic Pathway

(2018) Yosuke Okuno et al.   DIABETES

Mitochondrial oxidative stress causes insulin resistance without disrupting oxidative phosphorylation

(2018) Daniel J. Fazakerley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Obesity-Induced Protein Carbonylation In Murine Adipose Tissue Regulates The DNA Binding Domain Of Nuclear Zinc-Finger Proteins

(2018) Amy K Hauck et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The mitochondrial antioxidant SS-31 increases SIRT1 levels and ameliorates inflammation, oxidative stress and leukocyte-endothelium interactions in type 2 diabetes

(2018) Irene Escribano-Lopez et al.   Scientific Reports

Adipose oxidative stress and protein carbonylation

(2018) Amy K Hauck et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

4-hydroxynonenal causes impairment of human subcutaneous adipogenesis and induction of adipocyte insulin resistance

(2017) Mohamed A. Elrayess et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mitochondrial reactive oxygen species and adipose tissue thermogenesis: Bridging physiology and mechanisms

(2017) Edward T. Chouchani et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Treatment with antioxidants ameliorates oxidative damage in a mouse model of propionic acidemia

(2017) Ana Rivera-Barahona et al.   MOLECULAR GENETICS AND METABOLISM

Effects of Coenzyme Q10 on Markers of Inflammation: A Systematic Review and Meta-Analysis

(2017) Junya Zhai et al.   PLoS One

Perturbed adipose tissue hydrogen peroxide metabolism in centrally obese men: Association with insulin resistance

(2017) May G. Akl et al.   PLoS One

Protein oxidation and peroxidation

(2016) M. J. Davies   BIOCHEMICAL JOURNAL

Coenzyme Q biosynthesis in health and disease

(2016) Manuel Jesús Acosta et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Adipocyte-Specific Deletion of Manganese Superoxide Dismutase Protects From Diet-Induced Obesity Through Increased Mitochondrial Uncoupling and Biogenesis

(2016) Yong Hwan Han et al.   DIABETES

Mitochondrial ROS regulate thermogenic energy expenditure and sulfenylation of UCP1

(2016) Edward T. Chouchani et al.   NATURE

Interplay between oxidant species and energy metabolism

(2016) Celia Quijano et al.   Redox Biology

The mitochondrial-targeted antioxidant, MitoQ, increases liver mitochondrial cardiolipin content in obesogenic diet-fed rats

(2015) Gilles Fouret et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

In adipose tissue, increased mitochondrial emission of reactive oxygen species is important for short-term high-fat diet-induced insulin resistance in mice

(2015) Sabina Paglialunga et al.   DIABETOLOGIA

Redox signalling and mitochondrial stress responses; lessons from inborn errors of metabolism

(2015) Rikke K. J. Olsen et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Excessive caloric intake acutely causes oxidative stress, GLUT4 carbonylation, and insulin resistance in healthy men

(2015) Guenther Boden et al.   Science Translational Medicine

The mitochondrial-targeted antioxidant MitoQ ameliorates metabolic syndrome features in obesogenic diet-fed rats better than Apocynin or Allopurinol

(2014) Christine Feillet-Coudray et al.   FREE RADICAL RESEARCH

Metabolic control analysis of mitochondrial aconitase: influence over respiration and mitochondrial superoxide and hydrogen peroxide production

(2014) F. Scandroglio et al.   FREE RADICAL RESEARCH

Cellular consequences of oxidative stress in riboflavin responsive multiple acyl-CoA dehydrogenation deficiency patient fibroblasts

(2014) N. Cornelius et al.   HUMAN MOLECULAR GENETICS

The Chemical Uncoupler 2,4-Dinitrophenol (DNP) Protects against Diet-induced Obesity and Improves Energy Homeostasis in Mice at Thermoneutrality

(2014) Margalit Goldgof et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sestrin2 inhibits uncoupling protein 1 expression through suppressing reactive oxygen species

(2014) S.-H. Ro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hydrogen peroxide production regulates the mitochondrial function in insulin resistant muscle cells: Effect of catalase overexpression

(2013) Marina R. Barbosa et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Reversal of Hypertriglyceridemia, Fatty Liver Disease, and Insulin Resistance by a Liver-Targeted Mitochondrial Uncoupler

(2013) Rachel J. Perry et al.   Cell Metabolism

Mitochondrial Dynamics in the Regulation of Nutrient Utilization and Energy Expenditure

(2013) Marc Liesa et al.   Cell Metabolism

Antioxidant supplements and mortality

(2013) Goran Bjelakovic et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

"Deficiency" of Mitochondria in Muscle Does Not Cause Insulin Resistance

(2013) J. O. Holloszy   DIABETES

High-fat diet induces changes in adipose tissue trans-4-oxo-2-nonenal and trans-4-hydroxy-2-nonenal levels in a depot-specific manner

(2013) Eric K. Long et al.   FREE RADICAL BIOLOGY AND MEDICINE

Secondary coenzyme Q10 deficiency and oxidative stress in cultured fibroblasts from patients with riboflavin responsive multiple Acyl-CoA dehydrogenation deficiency

(2013) N. Cornelius et al.   HUMAN MOLECULAR GENETICS

Antioxidant Supplements to Prevent Mortality

(2013) Goran Bjelakovic et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Mitochondrial Respiration Regulates Adipogenic Differentiation of Human Mesenchymal Stem Cells

(2013) Yanmin Zhang et al.   PLoS One

Aconitase post-translational modification as a key in linkage between Krebs cycle, iron homeostasis, redox signaling, and metabolism of reactive oxygen species

(2013) Oleh V. Lushchak et al.   REDOX REPORT

Protein Carbonylation, Mitochondrial Dysfunction, and Insulin Resistance

(2013) Brigitte I. Frohnert et al.   Advances in Nutrition

Overexpression of manganese superoxide dismutase ameliorates high-fat diet-induced insulin resistance in rat skeletal muscle

(2012) Michael J. Boden et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

PPARγ agonists Induce a White-to-Brown Fat Conversion through Stabilization of PRDM16 Protein

(2012) Haruya Ohno et al.   Cell Metabolism

Role of physiological levels of 4-hydroxynonenal on adipocyte biology: implications for obesity and metabolic syndrome

(2012) Kalavathi Dasuri et al.   FREE RADICAL RESEARCH

Inactivation of Pyruvate Dehydrogenase Kinase 2 by Mitochondrial Reactive Oxygen Species

(2012) Thomas R. Hurd et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Recovery of MERRF Fibroblasts and Cybrids Pathophysiology by Coenzyme Q10

(2012) Mario De la Mata et al.   Neurotherapeutics

Protein carbonylation and metabolic control systems

(2012) Jessica M. Curtis et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Mitochondrial pharmacology

(2012) Robin A.J. Smith et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Peroxiredoxin-2 Upregulated by NF-κB Attenuates Oxidative Stress During the Differentiation of Muscle-Derived C2C12 Cells

(2011) Hyeran Won et al.   ANTIOXIDANTS & REDOX SIGNALING

AMPK-mediated increase of glycolysis as an adaptive response to oxidative stress in human cells: Implication of the cell survival in mitochondrial diseases

(2011) Shi-Bei Wu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Mitochondrial Complex III ROS Regulate Adipocyte Differentiation

(2011) Kathryn V. Tormos et al.   Cell Metabolism

Manganese Superoxide Dismutase: Guardian of the Powerhouse

(2011) Aaron K. Holley et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Increased Adipose Protein Carbonylation in Human Obesity

(2011) Brigitte I. Frohnert et al.   Obesity

Mitochondrial dysfunction in obesity

(2011) Juan C Bournat et al.   Current Opinion in Endocrinology Diabetes and Obesity

The Role of Mitochondria in Reactive Oxygen Species Metabolism and Signaling

(2010) Anatoly A. Starkov   Annals of the New York Academy of Sciences

Abdominal Subcutaneous Adipose Tissue: A Protective Fat Depot?

(2009) S. A. Porter et al.   DIABETES CARE

Reactive Oxygen Species Facilitate Adipocyte Differentiation by Accelerating Mitotic Clonal Expansion

(2009) Haemi Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chronic Peroxisome Proliferator-activated Receptor γ (PPARγ) Activation of Epididymally Derived White Adipocyte Cultures Reveals a Population of Thermogenically Competent, UCP1-containing Adipocytes Molecularly Distinct from Classic Brown Adipocytes

(2009) Natasa Petrovic et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans

(2009) Ethan J. Anderson et al.   JOURNAL OF CLINICAL INVESTIGATION

Mitochondrial development and the influence of its dysfunction during rat adipocyte differentiation

(2009) Rong-hua Lu et al.   MOLECULAR BIOLOGY REPORTS

Medium-chain fatty acids accumulating in MCAD deficiency elicit lipid and protein oxidative damage and decrease non-enzymatic antioxidant defenses in rat brain

(2009) Patrícia F. Schuck et al.   NEUROCHEMISTRY INTERNATIONAL

Proteomic Analysis of Human Adipose Tissue After Rosiglitazone Treatment Shows Coordinated Changes to Promote Glucose Uptake

(2009) Meftun Ahmed et al.   Obesity

How mitochondria produce reactive oxygen species

(2008) Michael P. Murphy   BIOCHEMICAL JOURNAL

Beneficial Effects of Subcutaneous Fat Transplantation on Metabolism

(2008) Thien T. Tran et al.   Cell Metabolism

FALDH Reverses the Deleterious Action of Oxidative Stress Induced by Lipid Peroxidation Product 4-Hydroxynonenal on Insulin Signaling in 3T3-L1 Adipocytes

(2008) D. Demozay et al.   DIABETES

Oxidative Stress and Covalent Modification of Protein with Bioactive Aldehydes

(2008) Paul A. Grimsrud et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

High-fat diets cause insulin resistance despite an increase in muscle mitochondria

(2008) C. R. Hancock et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA