Intravitreal Therapy Against the Complement Factor C5 Prevents Retinal Degeneration in an Experimental Autoimmune Glaucoma Model

Loss of retinal ganglion cells in a new genetic mouse model for primary open‐angle glaucoma

(2019) Sabrina Reinehr et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Fewer Functional Deficits and Reduced Cell Death after Ranibizumab Treatment in a Retinal Ischemia Model

(2018) Marina Palmhof et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

S100B immunization triggers NFκB and complement activation in an autoimmune glaucoma model

(2018) Sabrina Reinehr et al.   Scientific Reports

Concentration-Dependent Inner Retina Layer Damage and Optic Nerve Degeneration in a NMDA Model

(2017) Sandra Kuehn et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Cell-specific deletion of C1qa identifies microglia as the dominant source of C1q in mouse brain

(2017) Maria I. Fonseca et al.   Journal of Neuroinflammation

Real-World Results of Intravitreal Ranibizumab, Bevacizumab, or Triamcinolone for Diabetic Macular Edema

(2017) İrem Koç et al.   OPHTHALMOLOGICA

Protective effects on the retina after ranibizumab treatment in an ischemia model

(2017) Stephanie C. Joachim et al.   PLoS One

Therapeutic Inhibition of Complement: Well Worth the Risk

(2017) Scott R. Barnum   TRENDS IN PHARMACOLOGICAL SCIENCES

Optic Nerve Head Blood Flow, as Measured by Laser Speckle Flowgraphy, Is Significantly Reduced in Preperimetric Glaucoma

(2016) Yukihiro Shiga et al.   CURRENT EYE RESEARCH

Evaluating retinal ganglion cell loss and dysfunction

(2016) Ben Mead et al.   EXPERIMENTAL EYE RESEARCH

Early remodelling of the extracellular matrix proteins tenascin-C and phosphacan in retina and optic nerve of an experimental autoimmune glaucoma model

(2016) Sabrina Reinehr et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Retinal and Optic Nerve Damage is Associated with Early Glial Responses in an Experimental Autoimmune Glaucoma Model

(2016) Rozina Noristani et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Systemic ocular antigen immunization leads only to a minor secondary immune response

(2016) Sandra Kuehn et al.   JOURNAL OF NEUROIMMUNOLOGY

Simultaneous Complement Response via Lectin Pathway in Retina and Optic Nerve in an Experimental Autoimmune Glaucoma Model

(2016) Sabrina Reinehr et al.   Frontiers in Cellular Neuroscience

Exposure to the complement C5b-9 complex sensitizes 661W photoreceptor cells to both apoptosis and necroptosis

(2015) Hui Shi et al.   APOPTOSIS

Laser-induced ocular hypertension in adult rats does not affect non-RGC neurons in the ganglion cell layer but results in protracted severe loss of cone-photoreceptors

(2015) Arturo Ortín-Martínez et al.   EXPERIMENTAL EYE RESEARCH

S100 Alone Has the Same Destructive Effect on Retinal Ganglion Cells as in Combination with HSP 27 in an Autoimmune Glaucoma Model

(2015) Christina Casola et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Schwankungen des Augeninnendrucks, Blutdrucks und okulären Perfusionsdrucks bei Glaukompatienten

(2015) K. Spaniol et al.   KLINISCHE MONATSBLATTER FUR AUGENHEILKUNDE

The Pathophysiology and Treatment of Glaucoma

(2014) Robert N. Weinreb et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Combinatorial targeting of early pathways profoundly inhibits neurodegeneration in a mouse model of glaucoma

(2014) Gareth R. Howell et al.   NEUROBIOLOGY OF DISEASE

Komplementaktivierung nach Induktion einer okulären Hypertension im Tiermodell

(2014) S. Becker et al.   OPHTHALMOLOGE

Spectral-Domain Optical Coherence Tomography of the Rodent Eye: Highlighting Layers of the Outer Retina Using Signal Averaging and Comparison with Histology

(2014) Adeline Berger et al.   PLoS One

Apoptotic Retinal Ganglion Cell Death in an Autoimmune Glaucoma Model Is Accompanied by Antibody Depositions

(2013) Stephanie C. Joachim et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Deficiency of complement component 5 ameliorates glaucoma in DBA/2J mice

(2013) Gareth R Howell et al.   Journal of Neuroinflammation

Does autoimmunity play a part in the pathogenesis of glaucoma?

(2013) Katharina Bell et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Retinal ganglion cells: Energetics, compartmentation, axonal transport, cytoskeletons and vulnerability

(2013) Dao-Yi Yu et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Molecular clustering identifies complement and endothelin induction as early events in a mouse model of glaucoma

(2011) Gareth R. Howell et al.   JOURNAL OF CLINICAL INVESTIGATION

Complement mediated apoptosis leads to the loss of retinal ganglion cells in animal model of glaucoma

(2011) Purushottam Jha et al.   MOLECULAR IMMUNOLOGY

Changes in the inner and outer retinal layers after acute increase of the intraocular pressure in adult albino Swiss mice

(2010) Nicolás Cuenca et al.   EXPERIMENTAL EYE RESEARCH

Loss of retinal function in aged DBA/2J mice – New insights into retinal neurodegeneration

(2010) Peter Heiduschka et al.   EXPERIMENTAL EYE RESEARCH

The case for autoimmunity in glaucoma

(2010) Martin B. Wax   EXPERIMENTAL EYE RESEARCH

Systemic and local anti-C5 therapy reduces the disease severity in experimental autoimmune uveoretinitis

(2009) D. A. Copland et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Analysis of Autoantibodies Against Human Retinal Antigens in Sera of Patients with Glaucoma and Ocular Hypertension

(2008) Jan Reichelt et al.   CURRENT EYE RESEARCH

Sera of glaucoma patients show autoantibodies against myelin basic protein and complex autoantibody profiles against human optic nerve antigens

(2008) Stephanie C. Joachim et al.   GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

Autoimmunity and Glaucoma

(2008) Franz H. Grus et al.   JOURNAL OF GLAUCOMA

Induced Autoimmunity to Heat Shock Proteins Elicits Glaucomatous Loss of Retinal Ganglion Cell Neurons via Activated T-Cell-Derived Fas-Ligand

(2008) M. B. Wax et al.   JOURNAL OF NEUROSCIENCE