Multiple Pathways Involved in Palmitic Acid-Induced Toxicity: A System Biology Approach

Diet-Derived Fatty Acids, Brain Inflammation, and Mental Health

(2019) Helen M. Melo et al.   Frontiers in Neuroscience

Tibolone attenuates inflammatory response by palmitic acid and preserves mitochondrial membrane potential in astrocytic cells through estrogen receptor beta

(2019) Yeimy González-Giraldo et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

The astrocyte biochemistry

(2019) Débora G. Souza et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

The Synthetic Steroid Tibolone Decreases Reactive Gliosis and Neuronal Death in the Cerebral Cortex of Female Mice After a Stab Wound Injury

(2018) Andrea Crespo-Castrillo et al.   MOLECULAR NEUROBIOLOGY

A functional promoter variant of the human formimidoyltransferase cyclodeaminase (FTCD) gene is associated with working memory performance in young but not older adults.

(2018) Pamela M. Greenwood et al.   NEUROPSYCHOLOGY

The Saturated Fatty Acid Palmitate Induces Human Monocytic Cell Toxicity Toward Neuronal Cells: Exploring a Possible Link Between Obesity-Related Metabolic Impairments and Neuroinflammation

(2018) Jonathan P. Little et al.   JOURNAL OF ALZHEIMERS DISEASE

Cytochrome P450 27A1 Deficiency and Regional Differences in Brain Sterol Metabolism Cause Preferential Cholestanol Accumulation in the Cerebellum

(2017) Natalia Mast et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PDGF-BB Preserves Mitochondrial Morphology, Attenuates ROS Production, and Upregulates Neuroglobin in an Astrocytic Model Under Rotenone Insult

(2017) Ricardo Cabezas et al.   MOLECULAR NEUROBIOLOGY

Genome-Scale Reconstruction of the Human Astrocyte Metabolic Network

(2017) Cynthia A. Martín-Jiménez et al.   Frontiers in Aging Neuroscience

Estradiol Uses Different Mechanisms in Astrocytes from the Hippocampus of Male and Female Rats to Protect against Damage Induced by Palmitic Acid

(2017) Laura M. Frago et al.   Frontiers in Molecular Neuroscience

Fatty acid-induced astrocyte ketone production and the control of food intake

(2016) Christelle Le Foll et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Metabolic Control of Glia-Mediated Neuroinflammation

(2016) Mithilesh Kumar Jha et al.   Current Alzheimer Research

Novel insights into gliotransmitters

(2016) Francesco Petrelli et al.   CURRENT OPINION IN PHARMACOLOGY

Recon 2.2: from reconstruction to model of human metabolism

(2016) Neil Swainston et al.   Metabolomics

Tibolone protects astrocytic cells from glucose deprivation through a mechanism involving estrogen receptor beta and the upregulation of neuroglobin expression

(2016) Marco Avila-Rodriguez et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Quantification of Metabolic Rearrangements During Neural Stem Cells Differentiation into Astrocytes by Metabolic Flux Analysis

(2016) João V. Sá et al.   NEUROCHEMICAL RESEARCH

Astrocyte arachidonate and palmitate uptake and metabolism is differentially modulated by dibutyryl-cAMP treatment

(2016) D.R. Seeger et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Aerobic glycolysis promotes T helper 1 cell differentiation through an epigenetic mechanism

(2016) M. Peng et al.   SCIENCE

Fold-change threshold screening: a robust algorithm to unmask hidden gene expression patterns in noisy aggregated transcriptome data

(2015) Jonas Hausen et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Proteome- and Transcriptome-Driven Reconstruction of the Human Myocyte Metabolic Network and Its Use for Identification of Markers for Diabetes

(2015) Leif Väremo et al.   Cell Reports

Genome Scale Modeling in Systems Biology: Algorithms and Resources

(2014) Ali Najafi et al.   CURRENT GENOMICS

Tibolone protects T98G cells from glucose deprivation

(2014) Marco Ávila Rodriguez et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Estradiol for treatment-resistant schizophrenia: a large-scale randomized-controlled trial in women of child-bearing age

(2014) J Kulkarni et al.   MOLECULAR PSYCHIATRY

Saturated and trans fats and dementia: a systematic review

(2014) Neal D. Barnard et al.   NEUROBIOLOGY OF AGING

Metabolic control of cell death

(2014) D. R. Green et al.   SCIENCE

Fatty Acids in Energy Metabolism of the Central Nervous System

(2014) Alexander Panov et al.   Biomed Research International

Systematic analysis of transcription-level effects of neurodegenerative diseases on human brain metabolism by a newly reconstructed brain-specific metabolic network

(2014) Mustafa Sertbaş et al.   FEBS Open Bio

sybil – Efficient constraint-based modelling in R

(2013) Gabriel Gelius-Dietrich et al.   BMC Systems Biology

A community-driven global reconstruction of human metabolism

(2013) Ines Thiele et al.   NATURE BIOTECHNOLOGY

Multiple Roles for Astrocytes as Effectors of Cytokines and Inflammatory Mediators

(2013) Michael V. Sofroniew   NEUROSCIENTIST

Data, information, knowledge and principle: back to metabolism in KEGG

(2013) Minoru Kanehisa et al.   NUCLEIC ACIDS RESEARCH

Neuroinflammatory basis of metabolic syndrome

(2013) Sudarshana Purkayastha et al.   Molecular Metabolism

The Glutamate–Glutamine (GABA) Cycle: Importance of Late Postnatal Development and Potential Reciprocal Interactions between Biosynthesis and Degradation

(2013) Leif Hertz   Frontiers in Endocrinology

Alteration of glucose metabolism in cultured astrocytes after AQP9-small interference RNA application

(2012) Jérôme Badaut et al.   BRAIN RESEARCH

Saturated long-chain fatty acids activate inflammatory signaling in astrocytes

(2012) Sunita Gupta et al.   JOURNAL OF NEUROCHEMISTRY

Palmitate-activated astrocytes via serine palmitoyltransferase increase BACE1 in primary neurons by sphingomyelinases

(2012) Li Liu et al.   NEUROBIOLOGY OF AGING

The neuroprotective activity of tamoxifen and tibolone during glutathione depletion in vitro

(2012) I. F. Belenichev et al.   Neurochemical Journal

Primary Cultures of Astrocytes: Their Value in Understanding Astrocytes in Health and Disease

(2012) Sofie C. Lange et al.   NEUROCHEMICAL RESEARCH

Liver proteomics in progressive alcoholic steatosis

(2012) Harshica Fernando et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Histidine and arginine are associated with inflammation and oxidative stress in obese women

(2011) Yu-Cun Niu et al.   BRITISH JOURNAL OF NUTRITION

Pathogenic implications of iron accumulation in multiple sclerosis

(2011) Rachel Williams et al.   JOURNAL OF NEUROCHEMISTRY

Effect of chronic administration of estradiol, progesterone, and tibolone on the expression and phosphorylation of glycogen synthase kinase-3β and the microtubule-associated protein tau in the hippocampus and cerebellum of female rat

(2011) Rodolfo Pinto-Almazán et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Astrocytic-neuronal crosstalk: Implications for neuroprotection from brain injury

(2011) George E. Barreto et al.   NEUROSCIENCE RESEARCH

Aquaporins and Glia

(2010) Albertini Roberta et al.   Current Neuropharmacology

The biomass objective function

(2010) Adam M Feist et al.   CURRENT OPINION IN MICROBIOLOGY

Estrogen Stimulates Proliferation and Differentiation of Neural Stem/Progenitor Cells through Different Signal Transduction Pathways

(2010) Makiko Okada et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

What is flux balance analysis?

(2010) Jeffrey D Orth et al.   NATURE BIOTECHNOLOGY

A protocol for generating a high-quality genome-scale metabolic reconstruction

(2010) Ines Thiele et al.   Nature Protocols

Astroglial networks: a step further in neuroglial and gliovascular interactions

(2010) Christian Giaume et al.   NATURE REVIEWS NEUROSCIENCE

Entrez Gene: gene-centered information at NCBI

(2010) D. Maglott et al.   NUCLEIC ACIDS RESEARCH

TNF-α-induced aquaporin 9 in synoviocytes from patients with OA and RA

(2010) Masashizu Nagahara et al.   RHEUMATOLOGY

Flavonoids activated caspases for apoptosis in human glioblastoma T98G and U87MG cells but not in human normal astrocytes

(2009) Arabinda Das et al.   CANCER

Thein vivoneuron-to-astrocyte lactate shuttle in human brain: evidence from modeling of measured lactate levels during visual stimulation

(2009) Silvia Mangia et al.   JOURNAL OF NEUROCHEMISTRY

Identification of Astrocyte Secreted Proteins with a Combination of Shotgun Proteomics and Bioinformatics

(2009) James A. Dowell et al.   JOURNAL OF PROTEOME RESEARCH

Effects of high fat diet on Morris maze performance, oxidative stress, and inflammation in rats: Contributions of maternal diet

(2009) Christy L. White et al.   NEUROBIOLOGY OF DISEASE

GABA uptake-dependent Ca2+ signaling in developing olfactory bulb astrocytes

(2009) M. Doengi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Obesity and vulnerability of the CNS

(2008) Annadora J. Bruce-Keller et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Glutathione peroxidase 2 and aquaporin 8 as new markers for colonic inflammation in experimental colitis and inflammatory bowel diseases: an important role for H2O2?

(2008) Anje A. te Velde et al.   EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY

Biomarker discovery in neurodegenerative diseases: A proteomic approach

(2008) Min Shi et al.   NEUROBIOLOGY OF DISEASE

Mitochondrial Lactate Dehydrogenase Is Involved in Oxidative-Energy Metabolism in Human Astrocytoma Cells (CCF-STTG1)

(2008) Joseph Lemire et al.   PLoS One

Translational Systems Biology of Inflammation

(2008) Yoram Vodovotz et al.   PLoS Computational Biology