Quantum Dots and Gold Nanoparticles as Scaffolds for Enzymatic Enhancement: Recent Advances and the Influence of Nanoparticle Size

Functionalized gold nanoparticles for sample preparation: A review

(2019) Siyao Liu et al.   ELECTROPHORESIS

Multienzymatic Cascade Reactions via Enzyme Complex by Immobilization

(2019) Ee Taek Hwang et al.   ACS Catalysis

Nanoparticle Size Influences Localized Enzymatic Enhancement—A Case Study with Phosphotriesterase

(2019) Joyce C. Breger et al.   BIOCONJUGATE CHEMISTRY

Enhanced Catalysis from Multienzyme Cascades Assembled on a DNA Origami Triangle

(2019) William P. Klein et al.   ACS Nano

Artificial Multienzyme Scaffolds: Pursuing in Vitro Substrate Channeling with an Overview of Current Progress

(2019) Gregory A. Ellis et al.   ACS Catalysis

Environmental Decontamination of a Chemical Warfare Simulant Utilizing a Membrane Vesicle-Encapsulated Phosphotriesterase

(2018) Nathan J. Alves et al.   ACS Applied Materials & Interfaces

Characterizing the Surface Coverage of Protein-Gold Nanoparticle Bioconjugates

(2018) Rachel B. Kozlowski et al.   BIOCONJUGATE CHEMISTRY

The role of dynamic enzyme assemblies and substrate channelling in metabolic regulation

(2018) Lee J. Sweetlove et al.   Nature Communications

Multienzyme Cascade Reactions—Status and Recent Advances

(2018) Josef M. Sperl et al.   ACS Catalysis

Enhancing Coupled Enzymatic Activity by Colocalization on Nanoparticle Surfaces: Kinetic Evidence for Directed Channeling of Intermediates

(2018) James Nicholas Vranish et al.   ACS Nano

Detecting Biothreat Agents: From Current Diagnostics to Developing Sensor Technologies

(2018) Scott A. Walper et al.   ACS Sensors

Mimicking Cell Surface Enhancement of Protease Activity on the Surface of a Quantum Dot Nanoparticle

(2018) Tiffany Jeen et al.   BIOCONJUGATE CHEMISTRY

Time dependent HPLC analysis of the product ratio of enzymatically reduced prodrug CB1954 by a modified and immobilised nitroreductase

(2018) Patrick Ball et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Small Surface, Big Effects, and Big Challenges: Toward Understanding Enzymatic Activity at the Inorganic Nanoparticle–Substrate Interface

(2018) W. Russ Algar et al.   LANGMUIR

Inulinase immobilized gold-magnetic nanoparticles as a magnetically recyclable biocatalyst for facial and efficient inulin biotransformation to high fructose syrup

(2018) Maryam Mohammadi et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Combined cross-linked enzyme aggregates of horseradish peroxidase and glucose oxidase for catalyzing cascade chemical reactions

(2017) Le Truc Nguyen et al.   ENZYME AND MICROBIAL TECHNOLOGY

Pursuing the Promise of Enzymatic Enhancement with Nanoparticle Assemblies

(2017) James Nicholas Vranish et al.   LANGMUIR

Multifunctional gold nanoparticle layers for controllable capture and release of proteins

(2017) Zhenhua Li et al.   Nanoscale

Effect of size and curvature on the enzyme activity of bionanoconjugates

(2017) Sirimuvva Tadepalli et al.   Nanoscale

Enhancing coupled enzymatic activity by conjugating one enzyme to a nanoparticle

(2017) James N. Vranish et al.   Nanoscale

Taylor dispersion analysis, resonant mass measurement and bioactivity of pepsin-coated gold nanoparticles

(2017) Markus Höldrich et al.   TALANTA

Toward Rational Design of High-efficiency Enzyme Cascades

(2017) Yifei Zhang et al.   ACS Catalysis

Substrate Channeling in an Artificial Metabolon: A Molecular Dynamics Blueprint for an Experimental Peptide Bridge

(2017) Yuanchao Liu et al.   ACS Catalysis

Facile fabrication of lipase to amine functionalized gold nanoparticles to enhance stability and activity

(2017) Sristy Shikha et al.   RSC Advances

Dendrimeric DNA Nanostructures as Scaffolds for Efficient Bidirectional BRET-FRET Cascades

(2017) Carl W. Brown et al.   Advanced Optical Materials

Kinetic enhancement in high-activity enzyme complexes attached to nanoparticles

(2017) Anthony P. Malanoski et al.   Nanoscale Horizons

Direct Evidence for Metabolon Formation and Substrate Channeling in Recombinant TCA Cycle Enzymes

(2016) Beyza Bulutoglu et al.   ACS Chemical Biology

Gold nanoparticle-conjugated pepsin for efficient solution-like heterogeneous biocatalysis in analytical sample preparation protocols

(2016) Markus Höldrich et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Biomimicry Promotes the Efficiency of a 10-Step Sequential Enzymatic Reaction on Nanoparticles, Converting Glucose to Lactate

(2016) Chinatsu Mukai et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Energy Transfer with Semiconductor Quantum Dot Bioconjugates: A Versatile Platform for Biosensing, Energy Harvesting, and Other Developing Applications

(2016) Niko Hildebrandt et al.   CHEMICAL REVIEWS

Multifunctional nanoparticle–protein conjugates with controllable bioactivity and pH responsiveness

(2016) Feng Liu et al.   Nanoscale

Substrate channelling as an approach to cascade reactions

(2016) Ian Wheeldon et al.   Nature Chemistry

Nanocaged enzymes with enhanced catalytic activity and increased stability against protease digestion

(2016) Zhao Zhao et al.   Nature Communications

Proximity does not contribute to activity enhancement in the glucose oxidase–horseradish peroxidase cascade

(2016) Yifei Zhang et al.   Nature Communications

Protecting enzymatic function through directed packaging into bacterial outer membrane vesicles

(2016) Nathan J. Alves et al.   Scientific Reports

Acceleration of Proteolytic Activity Associated with Selection of Thiol Ligand Coatings on Quantum Dots

(2015) Miao Wu et al.   ACS Applied Materials & Interfaces

Temperature-Responsive Poly(N-isopropylacrylamide) Modified Gold Nanoparticle–Protein Conjugates for Bioactivity Modulation

(2015) Feng Liu et al.   ACS Applied Materials & Interfaces

Modulating the Activity of Protein Conjugated to Gold Nanoparticles by Site-Directed Orientation and Surface Density of Bound Protein

(2015) Feng Liu et al.   ACS Applied Materials & Interfaces

Understanding How Nanoparticle Attachment Enhances Phosphotriesterase Kinetic Efficiency

(2015) Joyce C. Breger et al.   ACS Nano

Effects of Nanoparticle Size on Multilayer Formation and Kinetics of Tethered Enzymes

(2015) James P. Lata et al.   BIOCONJUGATE CHEMISTRY

Quantum dot display enhances activity of a phosphotriesterase trimer

(2015) Joyce C. Breger et al.   CHEMICAL COMMUNICATIONS

Increasing the activity of immobilized enzymes with nanoparticle conjugation

(2015) Shaowei Ding et al.   CURRENT OPINION IN BIOTECHNOLOGY

Enzymatic bioconjugation of nanoparticles: developing specificity and control

(2015) Scott A Walper et al.   CURRENT OPINION IN BIOTECHNOLOGY

Probing the Enzymatic Activity of Alkaline Phosphatase within Quantum Dot Bioconjugates

(2015) Jonathan C. Claussen et al.   Journal of Physical Chemistry C

Novel materials through Nature's catalysts

(2015) Michael Richter et al.   Materials Today

Universal solvent restructuring induced by colloidal nanoparticles

(2015) M. Zobel et al.   SCIENCE

Enhanced Activity of Immobilized or Chemically Modified Enzymes

(2015) Yifei Zhang et al.   ACS Catalysis

Enzyme Catalytic Efficiency: A Function of Bio–Nano Interface Reactions

(2014) Alan S. Campbell et al.   ACS Applied Materials & Interfaces

Immobilized papain on gold nanorods as heterogeneous biocatalysts

(2014) Ahmad Homaei et al.   AMINO ACIDS

Cascade Biocatalysis by Multienzyme–Nanoparticle Assemblies

(2014) Wei Kang et al.   BIOCONJUGATE CHEMISTRY

Cell-free metabolic engineering: Biomanufacturing beyond the cell

(2014) Quentin M. Dudley et al.   Biotechnology Journal

A New Family of Pyridine-Appended Multidentate Polymers As Hydrophilic Surface Ligands for Preparing Stable Biocompatible Quantum Dots

(2014) Kimihiro Susumu et al.   CHEMISTRY OF MATERIALS

Modeling of Enhanced Catalysis in Multienzyme Nanostructures: Effect of Molecular Scaffolds, Spatial Organization, and Concentration

(2014) Christopher C. Roberts et al.   Journal of Chemical Theory and Computation

Interaction of colloidal nanoparticles with their local environment: the (ionic) nanoenvironment around nanoparticles is different from bulk and determines the physico-chemical properties of the nanoparticles

(2014) C. Pfeiffer et al.   Journal of the Royal Society Interface

Understanding enzymatic acceleration at nanoparticle interfaces: Approaches and challenges

(2014) Brandy J. Johnson et al.   Nano Today

Enzyme clustering accelerates processing of intermediates through metabolic channeling

(2014) Michele Castellana et al.   NATURE BIOTECHNOLOGY

Multi-enzyme complexes on DNA scaffolds capable of substrate channelling with an artificial swinging arm

(2014) Jinglin Fu et al.   Nature Nanotechnology

Origins of Activity Enhancement in Enzyme Cascades on Scaffolds

(2013) Ofer Idan et al.   ACS Nano

The Spatial Organization of Metabolism Within the Plant Cell

(2013) Lee J. Sweetlove et al.   Annual Review of Plant Biology

Quantum Dots in Bioanalysis: A Review of Applications across Various Platforms for Fluorescence Spectroscopy and Imaging

(2013) Eleonora Petryayeva et al.   APPLIED SPECTROSCOPY

Optimizing Protein Coordination to Quantum Dots with Designer Peptidyl Linkers

(2013) Kelly Boeneman Gemmill et al.   BIOCONJUGATE CHEMISTRY

Functionalizing Nanoparticles with Biological Molecules: Developing Chemistries that Facilitate Nanotechnology

(2013) Kim E. Sapsford et al.   CHEMICAL REVIEWS

Recent progress in the bioconjugation of quantum dots

(2013) Juan B. Blanco-Canosa et al.   COORDINATION CHEMISTRY REVIEWS

Engineering enzymatic cascades on nanoscale scaffolds

(2013) Ofer Idan et al.   CURRENT OPINION IN BIOTECHNOLOGY

Biomolecular scaffolds for enhanced signaling and catalytic efficiency

(2013) Rebecca Chen et al.   CURRENT OPINION IN BIOTECHNOLOGY

Chemical approaches for the construction of multi-enzyme reaction systems

(2013) Sanne Schoffelen et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Kinetic Enhancements in DNA–Enzyme Nanostructures Mimic the Sabatier Principle

(2013) Jyun-Liang Lin et al.   ACS Catalysis

Recyclable cellulose-containing magnetic nanoparticles: immobilization of cellulose-binding module-tagged proteins and a synthetic metabolon featuring substrate channeling

(2013) Suwan Myung et al.   Journal of Materials Chemistry B

Assembly of a Concentric Förster Resonance Energy Transfer Relay on a Quantum Dot Scaffold: Characterization and Application to Multiplexed Protease Sensing

(2012) W. Russ Algar et al.   ACS Nano

Bioconjugation of trypsin onto gold nanoparticles: Effect of surface chemistry on bioactivity

(2012) Helmut Hinterwirth et al.   ANALYTICA CHIMICA ACTA

Multiplexed Tracking of Protease Activity Using a Single Color of Quantum Dot Vector and a Time-Gated Förster Resonance Energy Transfer Relay

(2012) W. Russ Algar et al.   ANALYTICAL CHEMISTRY

Size-modulated synergy of cellulase clustering for enhanced cellulose hydrolysis

(2012) Shen-Long Tsai et al.   Biotechnology Journal

A novel approach for efficient immobilization and stabilization of papain on magnetic gold nanocomposites

(2012) Banalata Sahoo et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Quantum Dots as Simultaneous Acceptors and Donors in Time-Gated Förster Resonance Energy Transfer Relays: Characterization and Biosensing

(2012) W. Russ Algar et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Proteolytic Activity at Quantum Dot-Conjugates: Kinetic Analysis Reveals Enhanced Enzyme Activity and Localized Interfacial “Hopping”

(2012) W. Russ Algar et al.   NANO LETTERS

Engineering the third wave of biocatalysis

(2012) U. T. Bornscheuer et al.   NATURE

Semiconductor Quantum Dots in Bioanalysis: Crossing the Valley of Death

(2011) W. Russ Algar et al.   ANALYTICAL CHEMISTRY

The Controlled Display of Biomolecules on Nanoparticles: A Challenge Suited to Bioorthogonal Chemistry

(2011) W. Russ Algar et al.   BIOCONJUGATE CHEMISTRY

Potential applications of enzymes immobilized on/in nano materials: A review

(2011) Shakeel Ahmed Ansari et al.   BIOTECHNOLOGY ADVANCES

Size-modulated catalytic activity of enzyme–nanoparticle conjugates: a combined kinetic and theoretical study

(2011) Chung-Shu Wu et al.   CHEMICAL COMMUNICATIONS

Multifunctional Compact Zwitterionic Ligands for Preparing Robust Biocompatible Semiconductor Quantum Dots and Gold Nanoparticles

(2011) Kimihiro Susumu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Quantum Dot DNA Bioconjugates: Attachment Chemistry Strongly Influences the Resulting Composite Architecture

(2010) Kelly Boeneman et al.   ACS Nano

Beyond labels: A review of the application of quantum dots as integrated components of assays, bioprobes, and biosensors utilizing optical transduction

(2010) W. Russ Algar et al.   ANALYTICA CHIMICA ACTA

New opportunities in multiplexed optical bioanalyses using quantum dots and donor–acceptor interactions

(2010) W. Russ Algar et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Synthesis and characterization of enzyme–magnetic nanoparticle complexes: effect of size on activity and recovery

(2010) Hee Joon Park et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Graphene Oxide as a Matrix for Enzyme Immobilization

(2010) Jiali Zhang et al.   LANGMUIR

Functional Assembly of Minicellulosomes on the Saccharomyces cerevisiae Cell Surface for Cellulose Hydrolysis and Ethanol Production

(2009) S.-L. Tsai et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Synthetic protein scaffolds provide modular control over metabolic flux

(2009) John E Dueber et al.   NATURE BIOTECHNOLOGY

Enzyme cascades activated on topologically programmed DNA scaffolds

(2009) Ofer I. Wilner et al.   Nature Nanotechnology

DNA-directed assembly of artificial multienzyme complexes

(2008) Joachim Müller et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cohesin-dockerin microarray: Diverse specificities between two complementary families of interacting protein modules

(2008) Rachel Haimovitz et al.   PROTEOMICS