The aberrant expression of rhythm genes affects the genome instability and regulates the cancer immunity in pan‐cancer

Smad3 suppresses epithelial cell migration and proliferation via the clock gene Dec1, which negatively regulates the expression of clock genes Dec2 and Per1

(2019) Fuyuki Sato et al.   AMERICAN JOURNAL OF PATHOLOGY

Clinical relevance and significance of programmed death-ligand 1 expression, tumor-infiltrating lymphocytes, and p16 status in sinonasal squamous cell carcinoma

(2019) Huatao Quan et al.   Cancer Management and Research

The STAT3/NFIL3 signaling axis-mediated chemotherapy resistance is reversed by Raddeanin A via inducing apoptosis in choriocarcinoma cells

(2018) Zheng Peng et al.   JOURNAL OF CELLULAR PHYSIOLOGY

ImmPort, toward repurposing of open access immunological assay data for translational and clinical research

(2018) Sanchita Bhattacharya et al.   Scientific Data

Loss of circadian protein TIMELESS accelerates the progression of cellular senescence

(2018) Xiaomeng Shen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cistrome Data Browser: expanded datasets and new tools for gene regulatory analysis

(2018) Rongbin Zheng et al.   NUCLEIC ACIDS RESEARCH

Pan-cancer characterisation of microRNA across cancer hallmarks reveals microRNA-mediated downregulation of tumour suppressors

(2018) Andrew Dhawan et al.   Nature Communications

The genetics of circadian rhythms, sleep and health

(2017) Aarti Jagannath et al.   HUMAN MOLECULAR GENETICS

Constant light exposure impairs immune tolerance development in mice

(2017) Hiromi Mizutani et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

NFIL3 is a negative regulator of hepatic gluconeogenesis

(2017) Geon Kang et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

GEPIA: a web server for cancer and normal gene expression profiling and interactive analyses

(2017) Zefang Tang et al.   NUCLEIC ACIDS RESEARCH

Smad3 promotes cancer progression by inhibiting E4BP4-mediated NK cell development

(2017) Patrick Ming-Kuen Tang et al.   Nature Communications

Genomic and Transcriptomic Features of Response to Anti-PD-1 Therapy in Metastatic Melanoma

(2016) Willy Hugo et al.   CELL

Circadian Rhythm Disruption Promotes Lung Tumorigenesis

(2016) Thales Papagiannakopoulos et al.   Cell Metabolism

Cistrome Data Browser: a data portal for ChIP-Seq and chromatin accessibility data in human and mouse

(2016) Shenglin Mei et al.   NUCLEIC ACIDS RESEARCH

Clock gene Per2 as a controller of liver carcinogenesis

(2016) Ali Mteyrek et al.   Oncotarget

Performance evaluation for rapid detection of pan-cancer microsatellite instability with MANTIS

(2016) Esko A. Kautto et al.   Oncotarget

Circadian Clocks in the Immune System

(2015) Nathalie Labrecque et al.   JOURNAL OF BIOLOGICAL RHYTHMS

Robust enumeration of cell subsets from tissue expression profiles

(2015) Aaron M Newman et al.   NATURE METHODS

An IL-27/NFIL3 signalling axis drives Tim-3 and IL-10 expression and T-cell dysfunction

(2015) Chen Zhu et al.   Nature Communications

DNA damage shifts circadian clock time via Hausp-dependent Cry1 stabilization

(2015) Stephanie J Papp et al.   eLife

Circadian clock gene expression regulates cancer cell growth through glutaminase

(2014) A. Huang et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

MethHC: a database of DNA methylation and gene expression in human cancer

(2014) Wei-Yun Huang et al.   NUCLEIC ACIDS RESEARCH

Shifting the Circadian Rhythm of Feeding in Mice Induces Gastrointestinal, Metabolic and Immune Alterations Which Are Influenced by Ghrelin and the Core Clock Gene Bmal1

(2014) Jorien Laermans et al.   PLoS One

DNA Repair Pathway Gene Expression Score Correlates with Repair Proficiency and Tumor Sensitivity to Chemotherapy

(2014) S. P. Pitroda et al.   Science Translational Medicine

Casein kinase I epsilon interacts with mitochondrial proteins for the growth and survival of human ovarian cancer cells

(2012) Noah Rodriguez et al.   EMBO Molecular Medicine

The Circadian Clock Controls Toll-like Receptor 9-Mediated Innate and Adaptive Immunity

(2012) Adam C. Silver et al.   IMMUNITY

ROR1 Is Expressed in Human Breast Cancer and Associated with Enhanced Tumor-Cell Growth

(2012) Suping Zhang et al.   PLoS One

Clock Gene Expression Levels and Relationship With Clinical and Pathological Features in Colorectal Cancer Patients

(2011) G. Mazzoccoli et al.   CHRONOBIOLOGY INTERNATIONAL

Effects of sleep and circadian rhythm on the human immune system

(2010) Tanja Lange et al.   Annals of the New York Academy of Sciences

Circadian clock control of the cellular response to DNA damage

(2010) Aziz Sancar et al.   FEBS LETTERS

CK1ε Is Required for Breast Cancers Dependent on β-Catenin Activity

(2010) So Young Kim et al.   PLoS One

Testing the Circadian Gene Hypothesis in Prostate Cancer: A Population-Based Case-Control Study

(2009) Y. Zhu et al.   CANCER RESEARCH

Casein Kinase 1 Delta Regulates the Pace of the Mammalian Circadian Clock

(2009) J.-P. Etchegaray et al.   MOLECULAR AND CELLULAR BIOLOGY

A human B cell methylome at 100−base pair resolution

(2009) Tibor A. Rauch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A circadian clock in macrophages controls inflammatory immune responses

(2009) Maren Keller et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Anti-apoptotic and growth-stimulatory functions of CK1 delta and epsilon in ductal adenocarcinoma of the pancreas are inhibited by IC261 in vitro and in vivo

(2008) C Brockschmidt et al.   GUT

The Circadian Gene NPAS2, a Putative Tumor Suppressor, Is Involved in DNA Damage Response

(2008) A. E. Hoffman et al.   MOLECULAR CANCER RESEARCH