Memantine Protects From Exacerbation of Ischemic Stroke and Blood Brain Barrier Disruption in Mild But Not Severe Hyperhomocysteinemia

Hyperhomocysteinemia leads to exacerbation of ischemic brain damage: Role of GluN2A NMDA receptors

(2019) Ankur Jindal et al.   NEUROBIOLOGY OF DISEASE

Deficiency of superoxide dismutase promotes cerebral vascular hypertrophy and vascular dysfunction in hyperhomocysteinemia

(2017) Sanjana Dayal et al.   PLoS One

Quantification of urinary S- and N-homocysteinylated protein and homocysteine-thiolactone in mice

(2016) Hieronim Jakubowski   ANALYTICAL BIOCHEMISTRY

N-Homocysteinylation impairs collagen cross-linking in cystathionine β-synthase-deficient mice: a novel mechanism of connective tissue abnormalities

(2016) Joanna Perła-Kajan et al.   FASEB JOURNAL

Homocysteine lowering for stroke prevention: Unravelling the complexity of the evidence

(2016) J David Spence   International Journal of Stroke

Molecular and biochemical investigations of patients with intermediate or severe hyperhomocysteinemia

(2016) Jannie Tanderup Sørensen et al.   MOLECULAR GENETICS AND METABOLISM

Physiological Roles of Non-Neuronal NMDA Receptors

(2016) Adam D. Hogan-Cann et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

GluN2A Subunit-Containing NMDA Receptors Are the Preferential Neuronal Targets of Homocysteine

(2016) Dmitry A. Sibarov et al.   Frontiers in Cellular Neuroscience

Establishment and Dysfunction of the Blood-Brain Barrier

(2015) Zhen Zhao et al.   CELL

Genetic Ablation of Extra Domain A of Fibronectin in Hypercholesterolemic Mice Improves Stroke Outcome by Reducing Thrombo-InflammationCLINICAL PERSPECTIVE

(2015) Nirav Dhanesha et al.   CIRCULATION

Efficacy of Folic Acid Therapy in Primary Prevention of Stroke Among Adults With Hypertension in China

(2015) Yong Huo et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Elevated Total Homocysteine Levels in Acute Ischemic Stroke Are Associated With Long-Term Mortality

(2015) Zhihong Shi et al.   STROKE

Memantine Enhances Recovery From Stroke

(2014) Héctor E. López-Valdés et al.   STROKE

Homocysteine reduces NMDAR desensitization and differentially modulates peak amplitude of NMDAR currents, depending on GluN2 subunit composition

(2013) Andrew D. Bolton et al.   JOURNAL OF NEUROPHYSIOLOGY

NMDA receptor subunit diversity: impact on receptor properties, synaptic plasticity and disease

(2013) Pierre Paoletti et al.   NATURE REVIEWS NEUROSCIENCE

Opening of the Blood-Brain Barrier before Cerebral Pathology in Mild Hyperhomocysteinemia

(2013) Bryce C. Rhodehouse et al.   PLoS One

Meta-analysis of B vitamin supplementation on plasma homocysteine, cardiovascular and all-cause mortality

(2012) Tao Huang et al.   CLINICAL NUTRITION

Novel crosstalk between ERK MAPK and p38 MAPK leads to homocysteine-NMDA receptor-mediated neuronal cell death

(2012) Ranjana Poddar et al.   JOURNAL OF NEUROCHEMISTRY

Antiplatelet therapy and the effects of B vitamins in patients with previous stroke or transient ischaemic attack: a post-hoc subanalysis of VITATOPS, a randomised, placebo-controlled trial

(2012) Graeme J Hankey et al.   LANCET NEUROLOGY

Paradoxical absence of a prothrombotic phenotype in a mouse model of severe hyperhomocysteinemia

(2011) S. Dayal et al.   BLOOD

Hyperhomocysteinemia increases permeability of the blood-brain barrier by NMDA receptor-dependent regulation of adherens and tight junctions

(2011) R. S. Beard et al.   BLOOD

Efficacy of Homocysteine-Lowering Therapy With Folic Acid in Stroke Prevention

(2010) Meng Lee et al.   STROKE

Genetic or nutritional disorders in homocysteine or folate metabolism increase protein N-homocysteinylation in mice

(2009) Hieronim Jakubowski et al.   FASEB JOURNAL