Update from the laboratory: mechanistic studies of pathways of cancer-associated venous thrombosis using mouse models

Rivaroxaban for Thromboprophylaxis in High-Risk Ambulatory Patients with Cancer

(2019) Alok A. Khorana et al.   NEW ENGLAND JOURNAL OF MEDICINE

Citrullinated histone H3, a biomarker of neutrophil extracellular trap formation, predicts the risk of venous thromboembolism in cancer patients

(2018) L.-M. Mauracher et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Extracellular vesicles exposing tissue factor for the prediction of venous thromboembolism in patients with cancer: A prospective cohort study

(2018) Nick van Es et al.   THROMBOSIS RESEARCH

Comparison of microvesicle tissue factor activity in non-cancer severely ill patients and cancer patients

(2018) Yohei Hisada et al.   THROMBOSIS RESEARCH

Mouse models of cancer-associated thrombosis

(2018) Yohei Hisada et al.   THROMBOSIS RESEARCH

A clinical prediction model for cancer-associated venous thromboembolism: a development and validation study in two independent prospective cohorts

(2018) Ingrid Pabinger et al.   Lancet Haematology

Apixaban to Prevent Venous Thromboembolism in Patients with Cancer

(2018) Marc Carrier et al.   NEW ENGLAND JOURNAL OF MEDICINE

Human pancreatic tumors grown in mice release tissue factor-positive microvesicles that increase venous clot size

(2017) Y. Hisada et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Fibrin-bearing microparticles: marker of thrombo-embolic events in pancreatic and colorectal cancers

(2017) Diane Mege et al.   Oncotarget

Tumor-Derived Exosomes Induce the Formation of Neutrophil Extracellular Traps: Implications For The Establishment of Cancer-Associated Thrombosis

(2017) Ana C. Leal et al.   Scientific Reports

Intact Toll-like receptor 9 signaling in neutrophils modulates normal thrombogenesis in mice

(2016) Osama M. El-Sayed et al.   JOURNAL OF VASCULAR SURGERY

High-level secretion of tissue factor-rich extracellular vesicles from ovarian cancer cells mediated by filamin-A and protease-activated receptors

(2016) Shin Ito et al.   THROMBOSIS AND HAEMOSTASIS

Evaluation of US prescription patterns: Are treatment guidelines for cancer-associated venous thromboembolism being followed?

(2016) Alok A. Khorana et al.   THROMBOSIS RESEARCH

Priming of neutrophils toward NETosis promotes tumor growth

(2016) Mélanie Demers et al.   OncoImmunology

Venous Thromboembolism Prophylaxis and Treatment in Patients With Cancer: American Society of Clinical Oncology Clinical Practice Guideline Update 2014

(2015) Gary H. Lyman et al.   JOURNAL OF CLINICAL ONCOLOGY

Tissue factor expressed by circulating cancer cell-derived microparticles drastically increases the incidence of deep vein thrombosis in mice

(2015) G. M. Thomas et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Tissue factor-positive tumor microvesicles activate platelets and enhance thrombosis in mice

(2015) J. E. Geddings et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Incidence of venous thromboembolism (VTE) in ambulatory pancreatic cancer patients receiving chemotherapy and analysis of Khorana’s predictive model

(2014) A. J. Muñoz Martín et al.   Clinical & Translational Oncology

Epidemiology of cancer-associated venous thrombosis

(2013) J. F. Timp et al.   BLOOD

Microparticle association and heterogeneity of tumor-derived tissue factor in plasma: is it important for coagulation activation?

(2013) M. Davila et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Neutrophil histone modification by peptidylarginine deiminase 4 is critical for deep vein thrombosis in mice

(2013) K. Martinod et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Filamin-A is required for the incorporation of tissue factor into cell-derived microvesicles

(2013) Anthony Maraveyas et al.   THROMBOSIS AND HAEMOSTASIS

Circulating microparticle tissue factor, thromboembolism and survival in pancreaticobiliary cancers

(2013) Anubha Bharthuar et al.   THROMBOSIS RESEARCH

Neutrophil Extracellular Trap (NET) Impact on Deep Vein Thrombosis

(2012) Tobias A. Fuchs et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Critical Review of Mouse Models of Venous Thrombosis

(2012) Jose A. Diaz et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Tumor-derived tissue factor activates coagulation and enhances thrombosis in a mouse xenograft model of human pancreatic cancer

(2012) J.-G. Wang et al.   BLOOD

Microparticle-associated tissue factor activity, venous thromboembolism and mortality in pancreatic, gastric, colorectal and brain cancer patients

(2012) J. THALER et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Cancers predispose neutrophils to release extracellular DNA traps that contribute to cancer-associated thrombosis

(2012) M. Demers et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Membrane vesicles, current state-of-the-art: emerging role of extracellular vesicles

(2011) Bence György et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Defining MAP3 kinases required for MDA-MB-231 cell tumor growth and metastasis

(2011) M R Cronan et al.   ONCOGENE

Prediction of venous thromboembolism in cancer patients

(2010) C. Ay et al.   BLOOD

Cancer cell–derived microparticles bearing P-selectin glycoprotein ligand 1 accelerate thrombus formation in vivo

(2009) Grace M. Thomas et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Development and validation of a predictive model for chemotherapy-associated thrombosis

(2008) A. A. Khorana et al.   BLOOD

Plasma tissue factor may be predictive of venous thromboembolism in pancreatic cancer

(2008) A. A. KHORANA et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS