Distinct Immune Responses Elicited From Cervicovaginal Epithelial Cells by Lactic Acid and Short Chain Fatty Acids Associated With Optimal and Non-optimal Vaginal Microbiota

The evolving facets of bacterial vaginosis: implications for HIV transmission

(2019) Lyle R McKinnon et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

The vaginal microbiome and preterm birth

(2019) Jennifer M. Fettweis et al.   NATURE MEDICINE

The Cervicovaginal Microbiota-Host Interaction Modulates Chlamydia trachomatis Infection

(2019) Vonetta L. Edwards et al.   mBio

Evaluation of the association between the concentrations of key vaginal bacteria and the increased risk of HIV acquisition in African women from five cohorts: a nested case-control study

(2018) R Scott McClelland et al.   LANCET INFECTIOUS DISEASES

Anti-inflammatory effect of two Lactobacillus strains during infection with Gardnerella vaginalis and Candida albicans in a HeLa cell culture model

(2018) Carolina M. A. Santos et al.   MICROBIOLOGY-SGM

Anti-HIV-1 Activity of Lactic Acid in Human Cervicovaginal Fluid

(2018) David Tyssen et al.   mSphere

Lactobacillus -Deficient Cervicovaginal Bacterial Communities Are Associated with Increased HIV Acquisition in Young South African Women

(2017) Christina Gosmann et al.   IMMUNITY

Immunological function of Langerhans cells in HIV infection

(2017) Takamitsu Matsuzawa et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Vaginal lactic acid elicits an anti-inflammatory response from human cervicovaginal epithelial cells and inhibits production of pro-inflammatory mediators associated with HIV acquisition

(2017) A C Hearps et al.   Mucosal Immunology

The role of lactic acid production by probiotic Lactobacillus species in vaginal health

(2017) Gilda Tachedjian et al.   RESEARCH IN MICROBIOLOGY

Microbiome Composition and Function Drives Wound-Healing Impairment in the Female Genital Tract

(2016) Alexander S. Zevin et al.   PLoS Pathogens

Genital Inflammation and the Risk of HIV Acquisition in Women

(2015) Lindi Masson et al.   CLINICAL INFECTIOUS DISEASES

Vaginal microbiome and metabolome highlight specific signatures of bacterial vaginosis

(2015) B. Vitali et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

Cervicovaginal Bacteria Are a Major Modulator of Host Inflammatory Responses in the Female Genital Tract

(2015) Melis N. Anahtar et al.   IMMUNITY

Increased levels of inflammatory cytokines in the female reproductive tract are associated with altered expression of proteases, mucosal barrier proteins and an influx of HIV-susceptible target cells

(2015) Kelly B Arnold et al.   Mucosal Immunology

Cervicovaginal microbiome dysbiosis is associated with proteome changes related to alterations of the cervicovaginal mucosal barrier

(2015) H Borgdorff et al.   Mucosal Immunology

Metabolic Signatures of Bacterial Vaginosis

(2015) Sujatha Srinivasan et al.   mBio

Antimicrobial and immune modulatory effects of lactic acid and short chain fatty acids produced by vaginal microbiota associated with eubiosis and bacterial vaginosis

(2015) Muriel Aldunate et al.   Frontiers in Physiology

The Structure of the Human VaginalStratum Corneumand its Role in Immune Defense

(2014) Deborah J. Anderson et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Effects of Tenofovir on Cytokines and Nucleotidases in HIV-1 Target Cells and the Mucosal Tissue Environment in the Female Reproductive Tract

(2014) Nabanita Biswas et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Bacteria in the Vaginal Microbiome Alter the Innate Immune Response and Barrier Properties of the Human Vaginal Epithelia in a Species-Specific Manner

(2014) Sylvie Y. Doerflinger et al.   JOURNAL OF INFECTIOUS DISEASES

Lactobacilli Inactivate Chlamydia trachomatis through Lactic Acid but Not H2O2

(2014) Zheng Gong et al.   PLoS One

Defining genital tract cytokine signatures of sexually transmitted infections and bacterial vaginosis in women at high risk of HIV infection: a cross-sectional study

(2014) Lindi Masson et al.   SEXUALLY TRANSMITTED INFECTIONS

Theaflavin-3,3′-Digallate and Lactic Acid Combinations Reduce Herpes Simplex Virus Infectivity

(2013) Charles E. Isaacs et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Short-Chain Fatty Acids Activate GPR41 and GPR43 on Intestinal Epithelial Cells to Promote Inflammatory Responses in Mice

(2013) Myung H. Kim et al.   GASTROENTEROLOGY

Vaginal concentrations of lactic acid potently inactivate HIV

(2013) Muriel Aldunate et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Proteome profiles of vaginal fluids from women affected by bacterial vaginosis and healthy controls: outcomes of rifaximin treatment

(2013) F. Cruciani et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Degradation, Foraging, and Depletion of Mucus Sialoglycans by the Vagina-adaptedActinobacterium Gardnerella vaginalis

(2013) Warren G. Lewis et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Vaginal pH and Microbicidal Lactic Acid When Lactobacilli Dominate the Microbiota

(2013) Deirdre E. O’Hanlon et al.   PLoS One

Influence of Vaginal Bacteria and D- and L-Lactic Acid Isomers on Vaginal Extracellular Matrix Metalloproteinase Inducer: Implications for Protection against Upper Genital Tract Infections

(2013) S. S. Witkin et al.   mBio

Commensal Bacteria Modulate Innate Immune Responses of Vaginal Epithelial Cell Multilayer Cultures

(2012) William A. Rose et al.   PLoS One

Temporal Dynamics of the Human Vaginal Microbiota

(2012) P. Gajer et al.   Science Translational Medicine

Bacterial Vaginosis Associated with Increased Risk of Female-to-Male HIV-1 Transmission: A Prospective Cohort Analysis among African Couples

(2012) Craig R. Cohen et al.   PLOS MEDICINE

Short-Chain Fatty Acids Induce Pro-Inflammatory Cytokine Production Alone and in Combination with Toll-Like Receptor Ligands

(2011) Paria Mirmonsef et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

In vaginal fluid, bacteria associated with bacterial vaginosis can be suppressed with lactic acid but not hydrogen peroxide

(2011) Deirdre E O'Hanlon et al.   BMC INFECTIOUS DISEASES

The role of acidification in the inhibition of Neisseria gonorrhoeae by vaginal lactobacilli during anaerobic growth

(2011) Michelle A Graver et al.   Annals of Clinical Microbiology and Antimicrobials

Intravaginal Practices, Bacterial Vaginosis, and HIV Infection in Women: Individual Participant Data Meta-analysis

(2011) Nicola Low et al.   PLOS MEDICINE

The Effects of Commensal Bacteria on Innate Immune Responses in the Female Genital Tract

(2010) Paria Mirmonsef et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Suppressive effect of short-chain fatty acids on production of proinflammatory mediators by neutrophils

(2010) Marco A.R. Vinolo et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Vaginal microbiome of reproductive-age women

(2010) J. Ravel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bacterial vaginosis and HIV acquisition: a meta-analysis of published studies

(2009) Julius Atashili et al.   AIDS

The role of TLRs, NLRs and RLRs in mucosal innate immunity and homeostasis

(2009) E C Lavelle et al.   Mucosal Immunology

TNF-α and TLR agonists increase susceptibility to HIV-1 transmission by human Langerhans cells ex vivo

(2008) Marein A.W.P. de Jong et al.   JOURNAL OF CLINICAL INVESTIGATION

The Achilles Heel of the Trojan Horse Model of HIV-1 trans-Infection

(2008) Marielle Cavrois et al.   PLoS Pathogens