Mechanisms of Oral Bacterial Virulence Factors in Pancreatic Cancer

Cancer statistics, 2019

(2019) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

The microbiota and microbiome in pancreatic cancer: more influential than expected

(2019) Miao-Yan Wei et al.   Molecular Cancer

Tumor Microbiome Diversity and Composition Influence Pancreatic Cancer Outcomes

(2019) Erick Riquelme et al.   CELL

Commensal and Pathogenic Biofilms Alter Toll-Like Receptor Signaling in Reconstructed Human Gingiva

(2019) Lin Shang et al.   Frontiers in Cellular and Infection Microbiology

The fungal mycobiome promotes pancreatic oncogenesis via activation of MBL

(2019) Berk Aykut et al.   NATURE

The Pancreatic Cancer Microbiome Promotes Oncogenesis by Induction of Innate and Adaptive Immune Suppression

(2018) Smruti Pushalkar et al.   Cancer Discovery

Replication Study: Fusobacterium nucleatum infection is prevalent in human colorectal carcinoma

(2018) John Repass et al.   eLife

The Pivotal Role of DNA Repair in Infection Mediated-Inflammation and Cancer

(2018) Ayse Z. Sahan et al.   Frontiers in Microbiology

MicroRNA Roles in the Nuclear Factor Kappa B Signaling Pathway in Cancer

(2018) Jin’en Wu et al.   Frontiers in Immunology

Periodontal Pathogens and Associated Intrathecal Antibodies in Early Stages of Alzheimer’s Disease

(2018) Oliver Laugisch et al.   JOURNAL OF ALZHEIMERS DISEASE

“Do We Know Jack” About JAK? A Closer Look at JAK/STAT Signaling Pathway

(2018) Emira Bousoik et al.   Frontiers in Oncology

Rheumatoid Arthritis-Associated Autoimmunity Due to Aggregatibacter actinomycetemcomitans and Its Resolution With Antibiotic Therapy

(2018) Amarshi Mukherjee et al.   Frontiers in Immunology

Fusobacterium nucleatum Increases Proliferation of Colorectal Cancer Cells and Tumor Development in Mice by Activating Toll-Like Receptor 4 Signaling to Nuclear Factor−κB, and Up-regulating Expression of MicroRNA-21

(2017) Yongzhi Yang et al.   GASTROENTEROLOGY

Human oral microbiome and prospective risk for pancreatic cancer: a population-based nested case-control study

(2016) Xiaozhou Fan et al.   GUT

Pancreatic cancer

(2016) Terumi Kamisawa et al.   LANCET

Genotoxicity of Cytolethal Distending Toxin (CDT) on Isogenic Human Colorectal Cell Lines: Potential Promoting Effects for Colorectal Carcinogenesis

(2016) Vanessa Graillot et al.   Frontiers in Cellular and Infection Microbiology

Binding of the Fap2 Protein of Fusobacterium nucleatum to Human Inhibitory Receptor TIGIT Protects Tumors from Immune Cell Attack

(2015) Chamutal Gur et al.   IMMUNITY

Association of Fusobacterium species in pancreatic cancer tissues with molecular features and prognosis

(2015) Kei Mitsuhashi et al.   Oncotarget

PI3K Regulation of RAC1 Is Required for KRAS-Induced Pancreatic Tumorigenesis in Mice

(2014) Chia-Yen C. Wu et al.   GASTROENTEROLOGY

Active Invasion of Oral and Aortic Tissues by Porphyromonas gingivalis in Mice Causally Links Periodontitis and Atherosclerosis

(2014) Irina M. Velsko et al.   PLoS One

Oral Bacteria and Cancer

(2014) Sarah E. Whitmore et al.   PLoS Pathogens

Role of bacterial infections in pancreatic cancer

(2013) D. S. Michaud   CARCINOGENESIS

Fusobacterium nucleatum Promotes Colorectal Carcinogenesis by Modulating E-Cadherin/β-Catenin Signaling via its FadA Adhesin

(2013) Mara Roxana Rubinstein et al.   Cell Host & Microbe

Porphyromonas gingivalispromotes invasion of oral squamous cell carcinoma through induction of proMMP9 and its activation

(2013) Hiroaki Inaba et al.   CELLULAR MICROBIOLOGY

Aging, Cellular Senescence, and Cancer

(2012) Judith Campisi   Annual Review of Physiology

Gingival vascular functions are altered in type 2 diabetes mellitus model and/or periodontitis model

(2012) Shuta Sugiyama et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

A bacterial driver–passenger model for colorectal cancer: beyond the usual suspects

(2012) Harold Tjalsma et al.   NATURE REVIEWS MICROBIOLOGY

Porphyromonas gingivalis Induction of MicroRNA-203 Expression Controls Suppressor of Cytokine Signaling 3 in Gingival Epithelial Cells

(2011) Catherine E. Moffatt et al.   INFECTION AND IMMUNITY

Cytolethal distending toxin: a conserved bacterial genotoxin that blocks cell cycle progression, leading to apoptosis of a broad range of mammalian cell lineages

(2011) R. N. Jinadasa et al.   MICROBIOLOGY-SGM

Fusobacterium nucleatum adhesin FadA binds vascular endothelial cadherin and alters endothelial integrity

(2011) Yann Fardini et al.   MOLECULAR MICROBIOLOGY

Aggregatibacter actinomycetemcomitans Leukotoxin: A Powerful Tool with Capacity to Cause Imbalance in the Host Inflammatory Response

(2011) Anders Johansson   Toxins

The Senescence-Associated Secretory Phenotype: The Dark Side of Tumor Suppression

(2010) Jean-Philippe Coppé et al.   Annual Review of Pathology-Mechanisms of Disease

Helicobacter pylori in Autoimmune Pancreatitis and Pancreatic Carcinoma

(2010) Ralf Jesnowski et al.   PANCREATOLOGY

Aggregatibacter (Actinobacillus) actinomycetemcomitans: a triple A* periodontopathogen?

(2010) Brian Henderson et al.   PERIODONTOLOGY 2000

Escherichia coli induces DNA damage in vivo and triggers genomic instability in mammalian cells

(2010) G. Cuevas-Ramos et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ATP scavenging by the intracellular pathogen Porphyromonas gingivalis inhibits P2X7-mediated host-cell apoptosis

(2008) Özlem Yilmaz et al.   CELLULAR MICROBIOLOGY

A Bacterial Cytotoxin Identifies the RhoA Exchange Factor Net1 as a Key Effector in the Response to DNA Damage

(2008) Lina Guerra et al.   PLoS One