Genotoxicity of Cytolethal Distending Toxin (CDT) on Isogenic Human Colorectal Cell Lines: Potential Promoting Effects for Colorectal Carcinogenesis

The toxicity of theAggregatibacter actinomycetemcomitanscytolethal distending toxin correlates with its phosphatidylinositol-3,4,5-triphosphate phosphatase activity

(2015) Bruce J. Shenker et al.   CELLULAR MICROBIOLOGY

Phosphatidylinositol-3,4,5-Triphosphate and Cellular Signaling: Implications for Obesity and Diabetes

(2015) Prasenjit Manna et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Molecular mechanism of adenomatous polyposis coli-induced blockade of base excision repair pathway in colorectal carcinogenesis

(2015) Satya Narayan et al.   LIFE SCIENCES

Cytolethal distending toxin (CDT) is a radiomimetic agent and induces persistent levels of DNA double-strand breaks in human fibroblasts

(2014) Jörg Fahrer et al.   DNA REPAIR

Fusobacterium and Enterobacteriaceae: Important players for CRC?

(2014) Emma Allen-Vercoe et al.   IMMUNOLOGY LETTERS

Activated K-RAS and its effect on morphological appearance

(2014) Etsuko Kiyokawa et al.   JOURNAL OF BIOCHEMISTRY

The Cytolethal Distending Toxin Effects on Mammalian Cells: A DNA Damage Perspective

(2014) Elisabeth Bezine et al.   Cells

Breaking the Gingival Epithelial Barrier: Role of the Aggregatibacter actinomycetemcomitans Cytolethal Distending Toxin in Oral Infectious Disease

(2014) Joseph DiRienzo   Cells

Emerging roles of the microbiome in cancer

(2013) S. J. Bultman   CARCINOGENESIS

Colonization of the Human Gut by E. coli and Colorectal Cancer Risk

(2013) M. Bonnet et al.   CLINICAL CANCER RESEARCH

APC2 and Axin promote mitotic fidelity by facilitating centrosome separation and cytoskeletal regulation

(2013) J. S. Poulton et al.   DEVELOPMENT

High Prevalence of Mucosa-Associated E. coli Producing Cyclomodulin and Genotoxin in Colon Cancer

(2013) Emmanuel Buc et al.   PLoS One

Ionizing-radiation induced DNA double-strand breaks: A direct and indirect lighting up

(2013) Julien Vignard et al.   RADIOTHERAPY AND ONCOLOGY

From single-strand breaks to double-strand breaks during S-phase: a new mode of action of theEscherichia coli Cytolethal Distending Toxin

(2012) Y. Fedor et al.   CELLULAR MICROBIOLOGY

Chronic exposure to the cytolethal distending toxins of Gram-negative bacteria promotes genomic instability and altered DNA damage response

(2012) Riccardo Guidi et al.   CELLULAR MICROBIOLOGY

Genotoxicity of pesticide mixtures present in the diet of the French population

(2012) Vanessa Graillot et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Intestinal Inflammation Targets Cancer-Inducing Activity of the Microbiota

(2012) J. C. Arthur et al.   SCIENCE

Functional Parsing of Driver Mutations in the Colorectal Cancer Genome Reveals Numerous Suppressors of Anchorage-Independent Growth

(2011) U. Eskiocak et al.   CANCER RESEARCH

Cytolethal distending toxin: a conserved bacterial genotoxin that blocks cell cycle progression, leading to apoptosis of a broad range of mammalian cell lineages

(2011) R. N. Jinadasa et al.   MICROBIOLOGY-SGM

Immortalized Epithelial Cells Derived From Human Colon Biopsies Express Stem Cell Markers and Differentiate In Vitro

(2009) Andres I. Roig et al.   GASTROENTEROLOGY

Bacterial intoxication evokes cellular senescence with persistent DNA damage and cytokine signalling

(2009) Hana Blazkova et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

In vivovirulence properties of bacterial cytolethal-distending toxin

(2008) Zhongming Ge et al.   CELLULAR MICROBIOLOGY