Sphingosine 1-phosphate-regulated transcriptomes in heterogenous arterial and lymphatic endothelium of the aorta

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The single-cell transcriptional landscape of mammalian organogenesis

(2019) Junyue Cao et al.   NATURE

Single-Cell Transcriptional Profiling of Aortic Endothelium Identifies a Hierarchy from Endovascular Progenitors to Differentiated Cells

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Arterial Lymphatics in Atherosclerosis: Old Questions, New Insights, and Remaining Challenges

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Single-Cell Analysis of the Normal Mouse Aorta Reveals Functionally Distinct Endothelial Cell Populations

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High-endothelial cell-derived S1P regulates dendritic cell localization and vascular integrity in the lymph node

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Genetic Targeting of Organ-Specific Blood VesselsNovelty and Significance

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Endothelial Regeneration of Large Vessels Is a Biphasic Process Driven by Local Cells with Distinct Proliferative Capacities

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A molecular atlas of cell types and zonation in the brain vasculature

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Size-selective opening of the blood–brain barrier by targeting endothelial sphingosine 1–phosphate receptor 1

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Single-cell profiling reveals heterogeneity and functional patterning of GPCR expression in the vascular system

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Locally Triggered Release of the Chemokine CCL21 Promotes Dendritic Cell Transmigration across Lymphatic Endothelia

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Heterogeneity in the lymphatic vascular system and its origin

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Impaired endothelial barrier function in apolipoprotein M–deficient mice is dependent on sphingosine-1-phosphate receptor 1

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Phenotypic transformation of intimal and adventitial lymphatics in atherosclerosis: a regulatory role for soluble VEGF receptor 2

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Lineage-specific and single-cell chromatin accessibility charts human hematopoiesis and leukemia evolution

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Characterizing transcriptional heterogeneity through pathway and gene set overdispersion analysis

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Quantification of sphingosine 1-phosphate by validated LC-MS/MS method revealing strong correlation with apolipoprotein M in plasma but not in serum due to platelet activation during blood coagulation

(2015) Cecilia Frej et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Emerging biology of sphingosine-1-phosphate: its role in pathogenesis and therapy

(2015) Richard L. Proia et al.   JOURNAL OF CLINICAL INVESTIGATION

HDL-bound sphingosine 1-phosphate acts as a biased agonist for the endothelial cell receptor S1P1to limit vascular inflammation

(2015) Sylvain Galvani et al.   Science Signaling

HDL-bound sphingosine 1-phosphate acts as a biased agonist for the endothelial cell receptor S1P1to limit vascular inflammation

(2015) Sylvain Galvani et al.   Science Signaling

Sox7, Sox17, and Sox18 Cooperatively Regulate Vascular Development in the Mouse Retina

(2015) Yulian Zhou et al.   PLoS One

Molecular identification of venous progenitors in the dorsal aorta reveals an aortic origin for the cardinal vein in mammals

(2014) H. Lindskog et al.   DEVELOPMENT

Sphingosine-1-phosphate receptor 1 reporter mice reveal receptor activation sites in vivo

(2014) Mari Kono et al.   JOURNAL OF CLINICAL INVESTIGATION

Full-length RNA-seq from single cells using Smart-seq2

(2014) Simone Picelli et al.   Nature Protocols

Knockout of vascular early response gene worsens chronic stroke outcomes in neonatal mice

(2013) Mehwish A. Mirza et al.   BRAIN RESEARCH BULLETIN

Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position

(2013) Jason D Buenrostro et al.   NATURE METHODS

The Subread aligner: fast, accurate and scalable read mapping by seed-and-vote

(2013) Yang Liao et al.   NUCLEIC ACIDS RESEARCH

diffReps: Detecting Differential Chromatin Modification Sites from ChIP-seq Data with Biological Replicates

(2013) Li Shen et al.   PLoS One

Sox17 is indispensable for acquisition and maintenance of arterial identity

(2013) Monica Corada et al.   Nature Communications

Fractalkine: A Survivor's Guide

(2012) Gemma E. White et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

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(2012) Alexander Dobin et al.   BIOINFORMATICS

The Sphingosine-1-Phosphate Receptor S1PR1 Restricts Sprouting Angiogenesis by Regulating the Interplay between VE-Cadherin and VEGFR2

(2012) Konstantin Gaengel et al.   DEVELOPMENTAL CELL

Flow-Regulated Endothelial S1P Receptor-1 Signaling Sustains Vascular Development

(2012) Bongnam Jung et al.   DEVELOPMENTAL CELL

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(2012) Ben Langmead et al.   NATURE METHODS

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Engagement of S1P1-degradative mechanisms leads to vascular leak in mice

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Effects of Disturbed Flow on Vascular Endothelium: Pathophysiological Basis and Clinical Perspectives

(2011) Jeng-Jiann Chiu et al.   PHYSIOLOGICAL REVIEWS

Endothelium-protective sphingosine-1-phosphate provided by HDL-associated apolipoprotein M

(2011) C. Christoffersen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

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(2010) Brendan MacLean et al.   BIOINFORMATICS

BEDTools: a flexible suite of utilities for comparing genomic features

(2010) Aaron R. Quinlan et al.   BIOINFORMATICS

Increased Expression of  6 Integrin in Endothelial Cells Unveils a Proangiogenic Role for Basement Membrane

(2010) L. Primo et al.   CANCER RESEARCH

Loss of βarrestin1 and βarrestin2 contributes to pulmonary hypoplasia and neonatal lethality in mice

(2010) Mingfeng Zhang et al.   DEVELOPMENTAL BIOLOGY

Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities

(2010) Sven Heinz et al.   MOLECULAR CELL

Rapid, low-input, low-bias construction of shotgun fragment libraries by high-density in vitro transposition

(2010) Andrew Adey et al.   GENOME BIOLOGY

Immune and Inflammatory Mechanisms of Atherosclerosis

(2009) Elena Galkina et al.   Annual Review of Immunology

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(2009) M. D. Robinson et al.   BIOINFORMATICS

DLL1-mediated Notch activation regulates endothelial identity in mouse fetal arteries

(2009) I. Sorensen et al.   BLOOD

Sphingosine-1-phosphate in the plasma compartment regulates basal and inflammation-induced vascular leak in mice

(2009) Eric Camerer et al.   JOURNAL OF CLINICAL INVESTIGATION

Lymphatic endothelial cell sphingosine kinase activity is required for lymphocyte egress and lymphatic patterning

(2009) Trung H.M. Pham et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Quantitative proliferation dynamics and random chromosome segregation of hair follicle stem cells

(2008) Sanjeev K Waghmare et al.   EMBO JOURNAL

An essential role for Rac1 in endothelial cell function and vascular development

(2008) Wenfu Tan et al.   FASEB JOURNAL

Model-based Analysis of ChIP-Seq (MACS)

(2008) Yong Zhang et al.   GENOME BIOLOGY