Dzip1 and Fam92 form a ciliary transition zone complex with cell type specific roles in Drosophila

Centrosomal protein Dzip1l binds Cby, promotes ciliary bud formation, and acts redundantly with Bromi to regulate ciliogenesis in the mouse

(2018) Chengbing Wang et al.   DEVELOPMENT

An ordered pattern of Ana2 phosphorylation by Plk4 is required for centriole assembly

(2018) Tiffany A. McLamarrah et al.   JOURNAL OF CELL BIOLOGY

Centrobin is essential for C-tubule assembly and flagellum development inDrosophila melanogasterspermatogenesis

(2018) Jose Reina et al.   JOURNAL OF CELL BIOLOGY

Differential regulation of transition zone and centriole proteins contributes to ciliary base diversity

(2018) Swadhin Chandra Jana et al.   NATURE CELL BIOLOGY

A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies

(2018) David K. Breslow et al.   NATURE GENETICS

Drosophila PLP assembles pericentriolar clouds that promote centriole stability, cohesion and MT nucleation

(2018) Helio Roque et al.   PLoS Genetics

The “transition zone” of the cilium-like regions in the Drosophila spermatocytes and the role of the C-tubule in axoneme assembly

(2018) Marco Gottardo et al.   EXPERIMENTAL CELL RESEARCH

Phosphatidylinositol 4,5-bisphosphate regulates cilium transition zone maturation inDrosophila melanogaster

(2018) Alind Gupta et al.   JOURNAL OF CELL SCIENCE

A transient microtubule-based structure uncovers a new intrinsic asymmetry between the mother centrioles in the early Drosophila spermatocytes

(2018) Maria Giovanna Riparbelli et al.   Cytoskeleton

FAM92A Underlies Nonsyndromic Postaxial Polydactyly in Humans and an Abnormal Limb and Digit Skeletal Phenotype in Mice

(2018) Isabelle Schrauwen et al.   JOURNAL OF BONE AND MINERAL RESEARCH

The Ciliary Transition Zone: Finding the Pieces and Assembling the Gate

(2017) João Gonçalves et al.   MOLECULES AND CELLS

Transition Zone Migration: A Mechanism for Cytoplasmic Ciliogenesis and Postaxonemal Centriole Elongation

(2017) Tomer Avidor-Reiss et al.   Cold Spring Harbor Perspectives in Biology

Conditional knockout mice for the distal appendage protein CEP164 reveal its essential roles in airway multiciliated cell differentiation

(2017) Saul S. Siller et al.   PLoS Genetics

Asterless is required for centriole length control and sperm development

(2016) Brian J. Galletta et al.   JOURNAL OF CELL BIOLOGY

Transition zone assembly and its contribution to axoneme formation inDrosophilamale germ cells

(2016) Jennifer Vieillard et al.   JOURNAL OF CELL BIOLOGY

Drosophilasensory cilia lacking MKS proteins exhibit striking defects in development but only subtle defects in adults

(2016) Metta B. Pratt et al.   JOURNAL OF CELL SCIENCE

BAR Domain-Containing FAM92 Proteins Interact with Chibby1 To Facilitate Ciliogenesis

(2016) Feng-Qian Li et al.   MOLECULAR AND CELLULAR BIOLOGY

MKS5 and CEP290 Dependent Assembly Pathway of the Ciliary Transition Zone

(2016) Chunmei Li et al.   PLOS BIOLOGY

A genome-wide resource for the analysis of protein localisation in Drosophila

(2016) Mihail Sarov et al.   eLife

A Dynamic Protein Interaction Landscape of the Human Centrosome-Cilium Interface

(2015) Gagan D. Gupta et al.   CELL

Loss of Centrobin Enables Daughter Centrioles to Form Sensory Cilia in Drosophila

(2015) Marco Gottardo et al.   CURRENT BIOLOGY

The essential roles of transition fibers in the context of cilia

(2015) Qing Wei et al.   CURRENT OPINION IN CELL BIOLOGY

CEP290 alleles in mice disrupt tissue-specific cilia biogenesis and recapitulate features of syndromic ciliopathies

(2015) Rivka A. Rachel et al.   HUMAN MOLECULAR GENETICS

Cilia and Diseases

(2014) Jason M. Brown et al.   BIOSCIENCE

A Migrating Ciliary Gate Compartmentalizes the Site of Axoneme Assembly in Drosophila Spermatids

(2014) Marcus L. Basiri et al.   CURRENT BIOLOGY

Chibby promotes ciliary vesicle formation and basal body docking during airway cell differentiation

(2014) Michael C. Burke et al.   JOURNAL OF CELL BIOLOGY

hemingway is required for sperm flagella assembly and ciliary motility in Drosophila

(2014) Fabien Soulavie et al.   MOLECULAR BIOLOGY OF THE CELL

Cby1 promotes Ahi1 recruitment to a ring-shaped domain at the centriole–cilium interface and facilitates proper cilium formation and function

(2014) Yin Loon Lee et al.   MOLECULAR BIOLOGY OF THE CELL

C2cd3 is critical for centriolar distal appendage assembly and ciliary vesicle docking in mammals

(2014) Xuan Ye et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Essential role of Cenexin1, but not Odf2, in ciliogenesis

(2013) Jaerak Chang et al.   CELL CYCLE

Polo-like Kinase 4 Autodestructs by Generating Its Slimb-Binding Phosphodegron

(2013) Joseph E. Klebba et al.   CURRENT BIOLOGY

Highly Improved Gene Targeting by Germline-Specific Cas9 Expression in Drosophila

(2013) Shu Kondo et al.   GENETICS

Centrosomal Protein DZIP1 Regulates Hedgehog Signaling by Promoting Cytoplasmic Retention of Transcription Factor GLI3 and Affecting Ciliogenesis

(2013) Chengbing Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CP110 exhibits novel regulatory activities during centriole assembly inDrosophila

(2013) Anna Franz et al.   JOURNAL OF CELL BIOLOGY

The cilium-like region of the Drosophila spermatocyte: an emerging flagellum?

(2013) M. Gottardo et al.   JOURNAL OF CELL SCIENCE

Unique properties of Drosophila spermatocyte primary cilia

(2013) M. G. Riparbelli et al.   Biology Open

Klp10A, a Microtubule-Depolymerizing Kinesin-13, Cooperates with CP110 to Control Drosophila Centriole Length

(2012) Nathalie Delgehyr et al.   CURRENT BIOLOGY

Assembly and Persistence of Primary Cilia in Dividing Drosophila Spermatocytes

(2012) Maria Giovanna Riparbelli et al.   DEVELOPMENTAL CELL

The base of the cilium: roles for transition fibres and the transition zone in ciliary formation, maintenance and compartmentalization

(2012) Jeremy F Reiter et al.   EMBO REPORTS

Drosophila chibbyis required for basal body formation and ciliogenesis but not for Wg signaling

(2012) Camille Enjolras et al.   JOURNAL OF CELL BIOLOGY

A Wnt/beta-Catenin Pathway Antagonist Chibby Binds Cenexin at the Distal End of Mother Centrioles and Functions in Primary Cilia Formation

(2012) Nathan Steere et al.   PLoS One

The ciliary transition zone: from morphology and molecules to medicine

(2012) Peter G. Czarnecki et al.   TRENDS IN CELL BIOLOGY

Mapping the NPHP-JBTS-MKS Protein Network Reveals Ciliopathy Disease Genes and Pathways

(2011) Liyun Sang et al.   CELL

MKS and NPHP modules cooperate to establish basal body/transition zone membrane associations and ciliary gate function during ciliogenesis

(2011) Corey L. Williams et al.   JOURNAL OF CELL BIOLOGY

Dilatory is a Drosophila protein related to AZI1 (CEP131) that is located at the ciliary base and required for cilium formation

(2011) L. Ma et al.   JOURNAL OF CELL SCIENCE

A ciliopathy complex at the transition zone protects the cilia as a privileged membrane domain

(2011) Ben Chih et al.   NATURE CELL BIOLOGY

A transition zone complex regulates mammalian ciliogenesis and ciliary membrane composition

(2011) Francesc R Garcia-Gonzalo et al.   NATURE GENETICS

CEP290 tethers flagellar transition zone microtubules to the membrane and regulates flagellar protein content

(2010) Branch Craige et al.   JOURNAL OF CELL BIOLOGY

Making sense of cilia in disease: The human ciliopathies

(2009) Kate Baker et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS

The Zn Finger protein Iguana impacts Hedgehog signaling by promoting ciliogenesis

(2009) Andrew M. Glazer et al.   DEVELOPMENTAL BIOLOGY

The iguana/DZIP1 protein is a novel component of the ciliogenic pathway essential for axonemal biogenesis

(2009) Shang Yew Tay et al.   DEVELOPMENTAL DYNAMICS

A Proximal Centriole-Like Structure Is Present in Drosophila Spermatids and Can Serve as a Model to Study Centriole Duplication

(2009) S. Blachon et al.   GENETICS

A mouse model for Meckel syndrome reveals Mks1 is required for ciliogenesis and Hedgehog signaling

(2009) Scott D. Weatherbee et al.   HUMAN MOLECULAR GENETICS

Inactivation of Chibby affects function of motile airway cilia

(2009) Vera A. Voronina et al.   JOURNAL OF CELL BIOLOGY

High-throughput generation of tagged stable cell lines for proteomic analysis

(2009) Jorge Z. Torres et al.   PROTEOMICS

Centrioles in flies: The exception to the rule?

(2009) Delphine Gogendeau et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Efficient Ends-Out Gene Targeting In Drosophila

(2008) J. Huang et al.   GENETICS

Depletion of plasma membrane PtdIns(4,5)P2 reveals essential roles for phosphoinositides in flagellar biogenesis

(2008) H.-C. Wei et al.   JOURNAL OF CELL SCIENCE

Molecular Architecture of the Centriole Proteome: The Conserved WD40 Domain Protein POC1 Is Required for Centriole Duplication and Length Control

(2008) Lani C. Keller et al.   MOLECULAR BIOLOGY OF THE CELL