Centrosomal protein Dzip1l binds Cby, promotes ciliary bud formation, and acts redundantly with Bromi to regulate ciliogenesis in the mouse

Loss of dynein-2 intermediate chain Wdr34 results in defects in retrograde ciliary protein trafficking and Hedgehog signaling in the mouse

(2017) Chuanqing Wu et al.   HUMAN MOLECULAR GENETICS

Super-resolution microscopy reveals that disruption of ciliary transition-zone architecture causes Joubert syndrome

(2017) Xiaoyu Shi et al.   NATURE CELL BIOLOGY

Mutations in DZIP1L, which encodes a ciliary-transition-zone protein, cause autosomal recessive polycystic kidney disease

(2017) Hao Lu et al.   NATURE GENETICS

Genes and molecular pathways underpinning ciliopathies

(2017) Jeremy F. Reiter et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Cell Cycle-Related Kinase (CCRK) regulates ciliogenesis and Hedgehog signaling in mice

(2017) Ashley Snouffer et al.   PLoS Genetics

Centrosomal protein CP110 controls maturation of the mother centriole during cilia biogenesis

(2016) Sharda Prasad Yadav et al.   DEVELOPMENT

Transition zone assembly and its contribution to axoneme formation inDrosophilamale germ cells

(2016) Jennifer Vieillard et al.   JOURNAL OF CELL BIOLOGY

Primary Cilia and Mammalian Hedgehog Signaling

(2016) Fiona Bangs et al.   Cold Spring Harbor Perspectives in Biology

Open Sesame: How Transition Fibers and the Transition Zone Control Ciliary Composition

(2016) Francesc R. Garcia-Gonzalo et al.   Cold Spring Harbor Perspectives in Biology

MKS5 and CEP290 Dependent Assembly Pathway of the Ciliary Transition Zone

(2016) Chunmei Li et al.   PLOS BIOLOGY

TMEM107 Is a Critical Regulator of Ciliary Protein Composition and Is Mutated in Orofaciodigital Syndrome

(2015) Natalia A. Shylo et al.   HUMAN MUTATION

TMEM231, mutated in orofaciodigital and Meckel syndromes, organizes the ciliary transition zone

(2015) Elle C. Roberson et al.   JOURNAL OF CELL BIOLOGY

The transition zone protein Rpgrip1l regulates proteasomal activity at the primary cilium

(2015) Christoph Gerhardt et al.   JOURNAL OF CELL BIOLOGY

TMEM107 recruits ciliopathy proteins to subdomains of the ciliary transition zone and causes Joubert syndrome

(2015) Nils J. Lambacher et al.   NATURE CELL BIOLOGY

Protein C-terminal enzymatic labeling identifies novel caspase cleavages during the apoptosis of multiple myeloma cells induced by kinase inhibition

(2015) Wenwen Duan et al.   PROTEOMICS

Chibby promotes ciliary vesicle formation and basal body docking during airway cell differentiation

(2014) Michael C. Burke et al.   JOURNAL OF CELL BIOLOGY

Cby1 promotes Ahi1 recruitment to a ring-shaped domain at the centriole–cilium interface and facilitates proper cilium formation and function

(2014) Yin Loon Lee et al.   MOLECULAR BIOLOGY OF THE CELL

Talpid3-Binding Centrosomal Protein Cep120 Is Required for Centriole Duplication and Proliferation of Cerebellar Granule Neuron Progenitors

(2014) Chuanqing Wu et al.   PLoS One

C2cd3 is critical for centriolar distal appendage assembly and ciliary vesicle docking in mammals

(2014) Xuan Ye et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Centriole distal appendages promote membrane docking, leading to cilia initiation

(2013) B. E. Tanos et al.   GENES & DEVELOPMENT

Centrosomal Protein DZIP1 Regulates Hedgehog Signaling by Promoting Cytoplasmic Retention of Transcription Factor GLI3 and Affecting Ciliogenesis

(2013) Chengbing Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Two appendages homologous between basal bodies and centrioles are formed using distinctOdf2domains

(2013) Kazuhiro Tateishi et al.   JOURNAL OF CELL BIOLOGY

CEP162 is an axoneme-recognition protein promoting ciliary transition zone assembly at the cilia base

(2013) Won-Jing Wang et al.   NATURE CELL BIOLOGY

CCDC41 is required for ciliary vesicle docking to the mother centriole

(2013) K. Joo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dishevelled stabilization by the ciliopathy protein Rpgrip1l is essential for planar cell polarity

(2012) Alexia Mahuzier et al.   JOURNAL OF CELL BIOLOGY

Cep164 mediates vesicular docking to the mother centriole during early steps of ciliogenesis

(2012) Kerstin N. Schmidt et al.   JOURNAL OF CELL BIOLOGY

A size-exclusion permeability barrier and nucleoporins characterize a ciliary pore complex that regulates transport into cilia

(2012) Hooi Lynn Kee et al.   NATURE CELL BIOLOGY

A Wnt/beta-Catenin Pathway Antagonist Chibby Binds Cenexin at the Distal End of Mother Centrioles and Functions in Primary Cilia Formation

(2012) Nathan Steere et al.   PLoS One

Disruption of a Ciliary B9 Protein Complex Causes Meckel Syndrome

(2011) William E. Dowdle et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Mapping the NPHP-JBTS-MKS Protein Network Reveals Ciliopathy Disease Genes and Pathways

(2011) Liyun Sang et al.   CELL

Primary cilia and Gli3 activity regulate cerebral cortical size

(2011) Sandra L. Wilson et al.   Developmental Neurobiology

Generation and Characterization of Monoclonal Antibodies Against Human Chibby Protein

(2011) Benjamin Cyge et al.   HYBRIDOMA

MKS and NPHP modules cooperate to establish basal body/transition zone membrane associations and ciliary gate function during ciliogenesis

(2011) Corey L. Williams et al.   JOURNAL OF CELL BIOLOGY

Regulating the transition from centriole to basal body

(2011) Tetsuo Kobayashi et al.   JOURNAL OF CELL BIOLOGY

A ciliopathy complex at the transition zone protects the cilia as a privileged membrane domain

(2011) Ben Chih et al.   NATURE CELL BIOLOGY

The centrosome cycle: Centriole biogenesis, duplication and inherent asymmetries

(2011) Erich A. Nigg et al.   NATURE CELL BIOLOGY

Subcellular spatial regulation of canonical Wnt signalling at the primary cilium

(2011) Madeline A. Lancaster et al.   NATURE CELL BIOLOGY

A transition zone complex regulates mammalian ciliogenesis and ciliary membrane composition

(2011) Francesc R Garcia-Gonzalo et al.   NATURE GENETICS

Suppressor of fused and Spop regulate the stability, processing and function of Gli2 and Gli3 full-length activators but not their repressors

(2010) C. Wang et al.   DEVELOPMENT

Ofd1, a Human Disease Gene, Regulates the Length and Distal Structure of Centrioles

(2010) Veena Singla et al.   DEVELOPMENTAL CELL

Broad-Minded Links Cell Cycle-Related Kinase to Cilia Assembly and Hedgehog Signal Transduction

(2010) Hyuk Wan Ko et al.   DEVELOPMENTAL CELL

A Septin Diffusion Barrier at the Base of the Primary Cilium Maintains Ciliary Membrane Protein Distribution

(2010) Q. Hu et al.   SCIENCE

The Vertebrate Primary Cilium in Development, Homeostasis, and Disease

(2009) Jantje M. Gerdes et al.   CELL

Control of Centriole Length by CPAP and CP110

(2009) Thorsten I. Schmidt et al.   CURRENT BIOLOGY

Suppressor of Fused inhibits mammalian Hedgehog signaling in the absence of cilia

(2009) Jinping Jia et al.   DEVELOPMENTAL BIOLOGY

The Zn Finger protein Iguana impacts Hedgehog signaling by promoting ciliogenesis

(2009) Andrew M. Glazer et al.   DEVELOPMENTAL BIOLOGY

The iguana/DZIP1 protein is a novel component of the ciliogenic pathway essential for axonemal biogenesis

(2009) Shang Yew Tay et al.   DEVELOPMENTAL DYNAMICS

Cilium-independent regulation of Gli protein function by Sufu in Hedgehog signaling is evolutionarily conserved

(2009) M.-H. Chen et al.   GENES & DEVELOPMENT

Inactivation of Chibby affects function of motile airway cilia

(2009) Vera A. Voronina et al.   JOURNAL OF CELL BIOLOGY

Wnt signaling determines ventral spinal cord cell fates in a time-dependent manner

(2008) W. Yu et al.   DEVELOPMENT

Phosphorylation of Gli2 by protein kinase A is required for Gli2 processing and degradation and the Sonic Hedgehog-regulated mouse development

(2008) Yong Pan et al.   DEVELOPMENTAL BIOLOGY

A Crucial Role for Primary Cilia in Cortical Morphogenesis

(2008) M. A. Willaredt et al.   JOURNAL OF NEUROSCIENCE