Structural basis for COMPASS recognition of an H2B-ubiquitinated nucleosome

Structural Basis for Recognition of Ubiquitylated Nucleosome by Dot1L Methyltransferase

(2019) Cathy J. Anderson et al.   Cell Reports

Mechanism of Cross-talk between H2B Ubiquitination and H3 Methylation by Dot1L

(2019) Evan J. Worden et al.   CELL

Structural Basis of Dot1L Stimulation by Histone H2B Lysine 120 Ubiquitination

(2019) Marco Igor Valencia-Sánchez et al.   MOLECULAR CELL

Structural basis of nucleosome recognition and modification by MLL methyltransferases

(2019) Han Xue et al.   NATURE

Structural Basis of H2B Ubiquitination-Dependent H3K4 Methylation by COMPASS

(2019) Peter L. Hsu et al.   MOLECULAR CELL

SWISS-MODEL: homology modelling of protein structures and complexes

(2018) Andrew Waterhouse et al.   NUCLEIC ACIDS RESEARCH

Real-space refinement in PHENIX for cryo-EM and crystallography

(2018) Pavel V. Afonine et al.   Acta Crystallographica Section D-Structural Biology

Crystal Structure of the COMPASS H3K4 Methyltransferase Catalytic Module

(2018) Peter L. Hsu et al.   CELL

Structure and Conformational Dynamics of a COMPASS Histone H3K4 Methyltransferase Complex

(2018) Qianhui Qu et al.   CELL

New tools for automated high-resolution cryo-EM structure determination in RELION-3

(2018) Jasenko Zivanov et al.   eLife

biGBac enables rapid gene assembly for the expression of large multisubunit protein complexes

(2016) Florian Weissmann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

S-adenosyl methionine is necessary for inhibition of the methyltransferase G9a by the lysine 9 to methionine mutation on histone H3

(2016) Hariharan Jayaram et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural basis for histone H2B deubiquitination by the SAGA DUB module

(2016) M. T. Morgan et al.   SCIENCE

Nucleosome competition reveals processive acetylation by the SAGA HAT module

(2015) Alison E. Ringel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of a functional hotspot on ubiquitin required for stimulation of methyltransferase activity on chromatin

(2015) Matthew T. Holt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The n-SET Domain of Set1 Regulates H2B Ubiquitylation-Dependent H3K4 Methylation

(2013) Jaehoon Kim et al.   MOLECULAR CELL

Quantifying the local resolution of cryo-EM density maps

(2013) Alp Kucukelbir et al.   NATURE METHODS

Inhibition of PRC2 Activity by a Gain-of-Function H3 Mutation Found in Pediatric Glioblastoma

(2013) P. W. Lewis et al.   SCIENCE

The COMPASS Family of Histone H3K4 Methylases: Mechanisms of Regulation in Development and Disease Pathogenesis

(2012) Ali Shilatifard   Annual Review of Biochemistry

The Ubiquitin Code

(2012) David Komander et al.   Annual Review of Biochemistry

Asymmetrically Modified Nucleosomes

(2012) Philipp Voigt et al.   CELL

H2B monoubiquitylation is a 5′-enriched active transcription mark and correlates with exon–intron structure in human cells

(2012) Inkyung Jung et al.   GENOME RESEARCH

Nucleosome Structure(s) and Stability: Variations on a Theme

(2011) Andrew J. Andrews et al.   Annual Review of Biophysics

H2B ubiquitylation is part of chromatin architecture that marks exon-intron structure in budding yeast

(2011) Grace S Shieh et al.   BMC GENOMICS

Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation

(2011) Chuanbing Bian et al.   EMBO JOURNAL

Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega

(2011) F. Sievers et al.   Molecular Systems Biology

Histone H2B ubiquitylation disrupts local and higher-order chromatin compaction

(2011) Beat Fierz et al.   Nature Chemical Biology

Structural analysis of the core COMPASS family of histone H3K4 methylases from yeast to human

(2011) Y.-h. Takahashi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural and Biochemical Insights into MLL1 Core Complex Assembly

(2011) Vanja Avdic et al.   STRUCTURE

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Quantitative Interaction Proteomics and Genome-wide Profiling of Epigenetic Histone Marks and Their Readers

(2010) Michiel Vermeulen et al.   CELL

Structure of RCC1 chromatin factor bound to the nucleosome core particle

(2010) Ravindra D. Makde et al.   NATURE

Structure–Activity Analysis of Semisynthetic Nucleosomes: Mechanistic Insights into the Stimulation of Dot1L by Ubiquitylated Histone H2B

(2009) Robert K. McGinty et al.   ACS Chemical Biology

On the Mechanism of Multiple Lysine Methylation by the Human Mixed Lineage Leukemia Protein-1 (MLL1) Core Complex

(2009) Anamika Patel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Basis for the Requirement of Additional Factors for MLL1 SET Domain Activity and Recognition of Epigenetic Marks

(2009) Stacey M. Southall et al.   MOLECULAR CELL

DOT1L/KMT4 Recruitment and H3K79 Methylation Are Ubiquitously Coupled with Gene Transcription in Mammalian Cells

(2008) D. J. Steger et al.   MOLECULAR AND CELLULAR BIOLOGY

Chemically ubiquitylated histone H2B stimulates hDot1L-mediated intranucleosomal methylation

(2008) Robert K. McGinty et al.   NATURE

Monoubiquitinated H2B is associated with the transcribed region of highly expressed genes in human cells

(2008) Neri Minsky et al.   NATURE CELL BIOLOGY

A comprehensive library of histone mutants identifies nucleosomal residues required for H3K4 methylation

(2008) Shima Nakanishi et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY