JC Virus infected choroid plexus epithelial cells produce extracellular vesicles that infect glial cells independently of the virus attachment receptor

Picornavirus infection induces temporal release of multiple extracellular vesicle subsets that differ in molecular composition and infectious potential

(2019) Susanne G. van der Grein et al.   PLoS Pathogens

JC virus infection of meningeal and choroid plexus cells in patients with progressive multifocal leukoencephalopathy

(2019) Sarah M. Corbridge et al.   JOURNAL OF NEUROVIROLOGY

JC Polyomavirus Uses Extracellular Vesicles To Infect Target Cells

(2019) Jenna Morris-Love et al.   mBio

Genetic and Functional Dissection of the Role of Individual 5-HT2 Receptors as Entry Receptors for JC Polyomavirus

(2019) Benedetta Assetta et al.   Cell Reports

In vivo evidence for the contribution of peripheral circulating inflammatory exosomes to neuroinflammation

(2018) Jing Jing Li et al.   Journal of Neuroinflammation

Susceptibility of Primary Human Choroid Plexus Epithelial Cells and Meningeal Cells to Infection by JC Virus

(2018) Bethany A. O'Hara et al.   JOURNAL OF VIROLOGY

Exosomes serve as novel modes of tick-borne flavivirus transmission from arthropod to human cells and facilitates dissemination of viral RNA and proteins to the vertebrate neuronal cells

(2018) Wenshuo Zhou et al.   PLoS Pathogens

Vesicle-Cloaked Virus Clusters Are Optimal Units for Inter-organismal Viral Transmission

(2018) Marianita Santiana et al.   Cell Host & Microbe

BK Polyomavirus MicroRNA Levels in Exosomes Are Modulated by Non-Coding Control Region Activity and Down-Regulate Viral Replication When Delivered to Non-Infected Cells Prior to Infection

(2018) Francesco Martelli et al.   Viruses-Basel

Astrocyte EV-induced lincRNA-Cox2 regulates microglial phagocytosis: Implications for morphine-mediated potentiation of neurodegeneration

(2018) Guoku Hu et al.   Molecular Therapy-Nucleic Acids

Viral effects on the content and function of extracellular vesicles

(2017) Nancy Raab-Traub et al.   NATURE REVIEWS MICROBIOLOGY

Polyomavirus microRNAs circulating in biological fluids during viral persistence

(2017) Francesco Martelli et al.   REVIEWS IN MEDICAL VIROLOGY

Herpesviruses hijack host exosomes for viral pathogenesis

(2017) Sara Sadeghipour et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Infectious Entry and Neutralization of Pathogenic JC Polyomaviruses

(2017) Eileen M. Geoghegan et al.   Cell Reports

Progressive Multifocal Leukoencephalopathy: Endemic Viruses and Lethal Brain Disease

(2017) Sheila A. Haley et al.   Annual Review of Virology

Exosomes Derived from HIV-1 Infected DCs Mediate Viral trans-Infection via Fibronectin and Galectin-3

(2017) Rutuja Kulkarni et al.   Scientific Reports

Identification of a novel mechanism of blood–brain communication during peripheral inflammation via choroid plexus‐derived extracellular vesicles

(2016) Sriram Balusu et al.   EMBO Molecular Medicine

Reassessing the risk of natalizumab-associated PML

(2016) Joseph R. Berger et al.   JOURNAL OF NEUROVIROLOGY

The choroid plexus-cerebrospinal fluid interface in Alzheimer′s disease: more than just a barrier

(2016) RoosmarijnE Vandenbroucke et al.   Neural Regeneration Research

The Type I Interferon Response Determines Differences in Choroid Plexus Susceptibility between Newborns and Adults in Herpes Simplex Virus Encephalitis

(2016) Douglas R. Wilcox et al.   mBio

Human Polyomavirus Receptor Distribution in Brain Parenchyma Contrasts with Receptor Distribution in Kidney and Choroid Plexus

(2015) Sheila A. Haley et al.   AMERICAN JOURNAL OF PATHOLOGY

Infection Risk in Patients on Multiple Sclerosis Therapeutics

(2015) Eric M. Williamson et al.   CNS DRUGS

Modulation of Cellular Function Through Immune-Activated Exosomes

(2015) Lynn Pulliam et al.   DNA AND CELL BIOLOGY

The JCPYV DNA load inversely correlates with the viral microrna expression in blood and cerebrospinal fluid of patients at risk of PML

(2015) Arianna Rocca et al.   JOURNAL OF CLINICAL VIROLOGY

2nd International Conference on Progressive Multifocal Leukoencephalopathy (PML) 2015: JCV virology, progressive multifocal leukoencephalopathy pathogenesis, diagnosis and risk stratification, and new approaches to prevention and treatment

(2015) Andriani C. Patera et al.   JOURNAL OF NEUROVIROLOGY

The Greater Affinity of JC Polyomavirus Capsid for α2,6-Linked Lactoseries Tetrasaccharide c than for Other Sialylated Glycans Is a Major Determinant of Infectivity

(2015) Luisa J. Ströh et al.   JOURNAL OF VIROLOGY

JC polyomavirus mutants escape antibody-mediated neutralization

(2015) Upasana Ray et al.   Science Translational Medicine

Immune System Involvement in the Pathogenesis of JC Virus Induced PML: What is Learned from Studies of Patients with Underlying Diseases and Therapies as Risk Factors

(2015) Maria Chiara G. Monaco et al.   Frontiers in Immunology

A fatal case of JC virus meningitis presenting with hydrocephalus in a human immunodeficiency virus-seronegative patient

(2014) Shruti P. Agnihotri et al.   ANNALS OF NEUROLOGY

Extracellular Vesicle-Mediated Transfer of Genetic Information between the Hematopoietic System and the Brain in Response to Inflammation

(2014) Kirsten Ridder et al.   PLOS BIOLOGY

5-HT2 Receptors Facilitate JC Polyomavirus Entry

(2013) B. Assetta et al.   JOURNAL OF VIROLOGY

A pathogenic picornavirus acquires an envelope by hijacking cellular membranes

(2013) Zongdi Feng et al.   NATURE

A Retrograde Trafficking Inhibitor of Ricin and Shiga-Like Toxins Inhibits Infection of Cells by Human and Monkey Polyomaviruses

(2013) C. D. S. Nelson et al.   mBio

Choroid plexus transcytosis and exosome shuttling deliver folate into brain parenchyma

(2013) Marcel Grapp et al.   Nature Communications

Molecular Biology, Epidemiology, and Pathogenesis of Progressive Multifocal Leukoencephalopathy, the JC Virus-Induced Demyelinating Disease of the Human Brain

(2012) M. W. Ferenczy et al.   CLINICAL MICROBIOLOGY REVIEWS

Sequencing and Analysis of JC Virus DNA From Natalizumab-Treated PML Patients

(2011) Carl E. Reid et al.   JOURNAL OF INFECTIOUS DISEASES

Progressive Multifocal Leukoencephalopathy (PML) Development Is Associated With Mutations in JC Virus Capsid Protein VP1 That Change Its Receptor Specificity

(2011) Leonid Gorelik et al.   JOURNAL OF INFECTIOUS DISEASES

Structure-Function Analysis of the Human JC Polyomavirus Establishes the LSTc Pentasaccharide as a Functional Receptor Motif

(2010) Ursula Neu et al.   Cell Host & Microbe

Massive Secretion by T Cells Is Caused by HIV Nef in Infected Cells and by Nef Transfer to Bystander Cells

(2009) Claudia Muratori et al.   Cell Host & Microbe

Progressive multifocal leukoencephalopathy in HIV-1 infection

(2009) Paola Cinque et al.   LANCET INFECTIOUS DISEASES

The blood–brain barrier and immune function and dysfunction

(2009) William A. Banks et al.   NEUROBIOLOGY OF DISEASE

Reemergence of PML in Natalizumab-Treated Patients — New Cases, Same Concerns

(2009) Eugene O. Major   NEW ENGLAND JOURNAL OF MEDICINE

Adaptive Mutations in the JC Virus Protein Capsid Are Associated with Progressive Multifocal Leukoencephalopathy (PML)

(2009) Shamil R. Sunyaev et al.   PLoS Genetics