Overexpression of molecule GRP94 favors tumor progression in lung adenocarcinoma by interaction with regulatory T cells

Cancer statistics, 2018

(2018) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Lung cancer: current therapies and new targeted treatments

(2017) Fred R Hirsch et al.   LANCET

Mining expression and prognosis of topoisomerase isoforms in non-small-cell lung cancer by using Oncomine and Kaplan–Meier plotter

(2017) Guo-Xin Hou et al.   PLoS One

Cancer statistics in China, 2015

(2016) Wanqing Chen et al.   CA-A CANCER JOURNAL FOR CLINICIANS

The Role of the PERK/eIF2α/ATF4/CHOP Signaling Pathway in Tumor Progression During Endoplasmic Reticulum Stress

(2016) W. Rozpedek et al.   CURRENT MOLECULAR MEDICINE

Clients and Oncogenic Roles of Molecular Chaperone gp96/grp94

(2016) Ephraim A. Ansa-Addo et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Glutathione Peroxidase-1 Suppresses the Unfolded Protein Response upon Cigarette Smoke Exposure

(2016) Patrick Geraghty et al.   MEDIATORS OF INFLAMMATION

Emerging roles of T helper 17 and regulatory T cells in lung cancer progression and metastasis

(2016) Erin A. Marshall et al.   Molecular Cancer

Endoplasmic reticulum heat shock protein gp96/grp94 is a pro-oncogenic chaperone, not a tumor suppressor

(2015) Saleh Rachidi et al.   HEPATOLOGY

GP96 is a GARP chaperone and controls regulatory T cell functions

(2015) Yongliang Zhang et al.   JOURNAL OF CLINICAL INVESTIGATION

Endoplasmic reticulum heat shock protein gp96 maintains liver homeostasis and promotes hepatocellular carcinogenesis

(2015) Saleh Rachidi et al.   JOURNAL OF HEPATOLOGY

Molecular regulation of macrophages in unleashing cancer-related inflammation

(2014) Feng Hong et al.   OncoImmunology

Immune Chaperone gp96 Drives the Contributions of Macrophages to Inflammatory Colon Tumorigenesis

(2013) Crystal Morales et al.   CANCER RESEARCH

Molecular Chaperone gp96 Is a Novel Therapeutic Target of Multiple Myeloma

(2013) Y. Hua et al.   CLINICAL CANCER RESEARCH

Liver-specific knockout of GRP94 in mice disrupts cell adhesion, activates liver progenitor cells, and accelerates liver tumorigenesis

(2013) Wan-Ting Chen et al.   HEPATOLOGY

α7 Helix Region of αI Domain Is Crucial for Integrin Binding to Endoplasmic Reticulum Chaperone gp96

(2013) Feng Hong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Essential roles of grp94 in gut homeostasis via chaperoning canonical Wnt pathway

(2013) B. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tumor-Infiltrating Foxp3+ Regulatory T Cells are Correlated with Cyclooxygenase-2 Expression and are Associated with Recurrence in Resected Non-small Cell Lung Cancer

(2010) Katsuhiko Shimizu et al.   Journal of Thoracic Oncology

gp96, an endoplasmic reticulum master chaperone for integrins and Toll-like receptors, selectively regulates early T and B lymphopoiesis

(2009) M. Staron et al.   BLOOD

Cigarette smoke induces endoplasmic reticulum stress and the unfolded protein response in normal and malignant human lung cells

(2008) Ellen Jorgensen et al.   BMC CANCER