Behavioral characterization of a CRISPR-generated TRPA1 knockout rat in models of pain, itch, and asthma

Structural basis of cooling agent and lipid sensing by the cold-activated TRPM8 channel

(2019) Ying Yin et al.   SCIENCE

Mechanisms of pruritogen-induced activation of itch nerves in isolated mouse skin

(2017) F. Ru et al.   JOURNAL OF PHYSIOLOGY-LONDON

Methylglyoxal mediates streptozotocin-induced diabetic neuropathic pain via activation of the peripheral TRPA1 and Nav1.8 channels

(2016) Qian Huang et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Selective antagonism of TRPA1 produces limited efficacy in models of inflammatory- and neuropathic-induced mechanical hypersensitivity in rats

(2016) Sonya G Lehto et al.   Molecular Pain

Structure–activity relationships of the prototypical TRPM8 agonist icilin

(2015) Luciano De Petrocellis et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

TRPA1 as a drug target—promise and challenges

(2015) Jun Chen et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Tmem100 Is a Regulator of TRPA1-TRPV1 Complex and Contributes to Persistent Pain

(2015) Hao-Jui Weng et al.   NEURON

HTR7 Mediates Serotonergic Acute and Chronic Itch

(2015) Takeshi Morita et al.   NEURON

The role of TRPA1 in muscle pain and mechanical hypersensitivity under inflammatory conditions in rats

(2015) J. Asgar et al.   NEUROSCIENCE

Identification of a novel 2-pyridyl-benzensulfonamide derivative, RQ-00203078, as a selective and orally active TRPM8 antagonist

(2014) Masashi Ohmi et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Monocytes expressing CX3CR1 orchestrate the development of vincristine-induced pain

(2014) Elizabeth A. Old et al.   JOURNAL OF CLINICAL INVESTIGATION

Direct evidence for functional TRPV1/TRPA1 heteromers

(2014) Michael J. M. Fischer et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Novel Therapeutic Strategy to Prevent Chemotherapy-Induced Persistent Sensory Neuropathy By TRPA1 Blockade

(2013) G. Trevisan et al.   CANCER RESEARCH

The Ion Channel TRPA1 Is Required for Chronic Itch

(2013) S. R. Wilson et al.   JOURNAL OF NEUROSCIENCE

Species differences and molecular determinant of TRPA1 cold sensitivity

(2013) Jun Chen et al.   Nature Communications

TRPA1-like channels enhance glycinergic transmission in medullary dorsal horn neurons

(2012) Jin-Hwa Cho et al.   JOURNAL OF NEUROCHEMISTRY

A Novel Behavioral Assay for Measuring Cold Sensation in Mice

(2012) Daniel S. Brenner et al.   PLoS One

TRPA1 Mediates Mechanical Sensitization in Nociceptors during Inflammation

(2012) Richard C. Lennertz et al.   PLoS One

TRPA1 Is Functionally Expressed Primarily by IB4-Binding, Non-Peptidergic Mouse and Rat Sensory Neurons

(2012) Marie E. Barabas et al.   PLoS One

TRPA1 is required for histamine-independent, Mas-related G protein–coupled receptor–mediated itch

(2011) Sarah R Wilson et al.   NATURE NEUROSCIENCE

Oxaliplatin elicits mechanical and cold allodynia in rodents via TRPA1 receptor stimulation

(2011) Romina Nassini et al.   PAIN

Contribution of TRPV1-TRPA1 Interaction to the Single Channel Properties of the TRPA1 Channel

(2010) Alexander Staruschenko et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TRPM8, but not TRPA1, is required for neural and behavioral responses to acute noxious cold temperatures and cold-mimetics in vivo

(2010) Wendy M. Knowlton et al.   PAIN

TRPA1-mediated responses in trigeminal sensory neurons: interaction between TRPA1 and TRPV1

(2009) Margaux M. Salas et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

A sensory neuronal ion channel essential for airway inflammation and hyperreactivity in asthma

(2009) A. I. Caceres et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TRPA1 is a major oxidant sensor in murine airway sensory neurons

(2008) Bret F. Bessac et al.   JOURNAL OF CLINICAL INVESTIGATION

TRPA1 Channels Mediate Cold Temperature Sensing in Mammalian Vagal Sensory Neurons: Pharmacological and Genetic Evidence

(2008) O. Fajardo et al.   JOURNAL OF NEUROSCIENCE

HC-030031, a TRPA1 Selective Antagonist, Attenuates Inflammatory- and Neuropathy-Induced Mechanical Hypersensitivity

(2008) Samer R Eid et al.   Molecular Pain