Colorectal cancers utilize glutamine as an anaplerotic substrate of the TCA cycle in vivo
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Title
Colorectal cancers utilize glutamine as an anaplerotic substrate of the TCA cycle in vivo
Authors
Keywords
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Journal
Scientific Reports
Volume 9, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2019-12-16
DOI
10.1038/s41598-019-55718-2
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Note: Only part of the references are listed.- Glutaminase inhibition improves FLT3 inhibitor therapy for acute myeloid leukemia
- (2018) Mark A. Gregory et al. EXPERIMENTAL HEMATOLOGY
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- (2018) Jennifer Rachel Eads et al. JOURNAL OF CLINICAL ONCOLOGY
- CANTATA: A randomized phase 2 study of CB-839 in combination with cabozantinib vs. placebo with cabozantinib in patients with advanced/metastatic renal cell carcinoma.
- (2018) Nizar M. Tannir et al. JOURNAL OF CLINICAL ONCOLOGY
- Glucose feeds the TCA cycle via circulating lactate
- (2017) Sheng Hui et al. NATURE
- PTEN Regulates Glutamine Flux to Pyrimidine Synthesis and Sensitivity to Dihydroorotate Dehydrogenase Inhibition
- (2017) Deepti Mathur et al. Cancer Discovery
- Environment Impacts the Metabolic Dependencies of Ras-Driven Non-Small Cell Lung Cancer
- (2016) Shawn M. Davidson et al. Cell Metabolism
- Combination therapy with BPTES nanoparticles and metformin targets the metabolic heterogeneity of pancreatic cancer
- (2016) Amira Elgogary et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Oncogenic PIK3CA mutations reprogram glutamine metabolism in colorectal cancer
- (2016) Yujun Hao et al. Nature Communications
- Regulation of paxillin-p130-PI3K-AKT signaling axis by Src and PTPRT impacts colon tumorigenesis
- (2016) Yiqing Zhao et al. Oncotarget
- The chemokine receptor CCR6 facilitates the onset of mammary neoplasia in the MMTV-PyMT mouse model via recruitment of tumor-promoting macrophages
- (2015) Sarah T. Boyle et al. Molecular Cancer
- Regulation of mammalian nucleotide metabolism and biosynthesis
- (2015) Andrew N. Lane et al. NUCLEIC ACIDS RESEARCH
- Molecular Pathways: Intercellular PTEN and the Potential of PTEN Restoration Therapy
- (2014) B. D. Hopkins et al. CLINICAL CANCER RESEARCH
- Antitumor Activity of the Glutaminase Inhibitor CB-839 in Triple-Negative Breast Cancer
- (2014) M. I. Gross et al. MOLECULAR CANCER THERAPEUTICS
- Sox9 Induction, Ectopic Paneth Cells, and Mitotic Spindle Axis Defects in Mouse Colon Adenomatous Epithelium Arising From Conditional Biallelic Apc Inactivation
- (2013) Ying Feng et al. AMERICAN JOURNAL OF PATHOLOGY
- Patient-Derived Tumor Xenografts: Transforming Clinical Samples into Mouse Models
- (2013) D. Siolas et al. CANCER RESEARCH
- Analysis of Tumor Metabolism Reveals Mitochondrial Glucose Oxidation in Genetically Diverse Human Glioblastomas in the Mouse Brain In Vivo
- (2012) Isaac Marin-Valencia et al. Cell Metabolism
- Novel mutations target distinct subgroups of medulloblastoma
- (2012) Giles Robinson et al. NATURE
- Hyperinsulinemic-euglycemic Clamps in Conscious, Unrestrained Mice
- (2011) Julio E. Ayala et al. Jove-Journal of Visualized Experiments
- Identification and functional characterization of paxillin as a target of protein tyrosine phosphatase receptor T
- (2010) Y. Zhao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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