Structural and biochemical basis of the formation of isoaspartate in the complementarity-determining region of antibody 64M-5 Fab
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Title
Structural and biochemical basis of the formation of isoaspartate in the complementarity-determining region of antibody 64M-5 Fab
Authors
Keywords
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Journal
Scientific Reports
Volume 9, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2019-12-06
DOI
10.1038/s41598-019-54918-0
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Note: Only part of the references are listed.- Structures of the antibody 64M-5 Fab and its complex with dT(6–4)T indicate induced-fit and high-affinity mechanisms
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- Structure of the DNA (6–4) photoproduct dTT(6–4)TT in complex with the 64M-2 antibody Fab fragment implies increased antibody-binding affinity by the flanking nucleotides
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