Protective Role of Shiitake Mushroom-Derived Exosome-Like Nanoparticles in D-Galactosamine and Lipopolysaccharide-Induced Acute Liver Injury in Mice

Exosome-like Nanoparticles from Ginger Rhizomes Inhibited NLRP3 Inflammasome Activation

(2019) Xingyi Chen et al.   MOLECULAR PHARMACEUTICS

Nuclear Receptor Subfamily 1 Group D Member 1 Regulates Circadian Activity of NLRP3 Inflammasome to Reduce the Severity of Fulminant Hepatitis in Mice

(2018) Benoit Pourcet et al.   GASTROENTEROLOGY

Isolation of Exosome-Like Nanoparticles and Analysis of MicroRNAs Derived from Coconut Water Based on Small RNA High-Throughput Sequencing

(2018) Zhehao Zhao et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

A diet defined by its content of bovine milk exosomes and their RNA cargos has moderate effects on gene expression, amino acid profiles and grip strength in skeletal muscle in C57BL/6 mice

(2018) Amy Leiferman et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

ARMMs as a versatile platform for intracellular delivery of macromolecules

(2018) Qiyu Wang et al.   Nature Communications

AMSC-derived exosomes alleviate lipopolysaccharide/d-galactosamine-induced acute liver failure by miR-17-mediated reduction of TXNIP/NLRP3 inflammasome activation in macrophages

(2018) Yanning Liu et al.   EBioMedicine

Plant-Derived Exosomal MicroRNAs Shape the Gut Microbiota

(2018) Yun Teng et al.   Cell Host & Microbe

RORγ regulates the NLRP3 inflammasome

(2018) Cyrielle Billon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Apple-Derived Nanoparticles Modulate Expression of Organic-Anion-Transporting Polypeptide (OATP) 2B1 in Caco-2 Cells

(2018) Daichi Fujita et al.   MOLECULAR PHARMACEUTICS

Milk-Derived Exosomes and Metabolic Regulation

(2018) Janos Zempleni et al.   Annual Review of Animal Biosciences

Broccoli-Derived Nanoparticle Inhibits Mouse Colitis by Activating Dendritic Cell AMP-Activated Protein Kinase

(2017) Zhongbin Deng et al.   MOLECULAR THERAPY

Lentinan from shiitake selectively attenuates AIM2 and non-canonical inflammasome activation while inducing pro-inflammatory cytokine production

(2017) Huijeong Ahn et al.   Scientific Reports

Edible ginger-derived nanoparticles: A novel therapeutic approach for the prevention and treatment of inflammatory bowel disease and colitis-associated cancer

(2016) Mingzhen Zhang et al.   BIOMATERIALS

Bovine milk-derived exosomes for drug delivery

(2016) Radha Munagala et al.   CANCER LETTERS

Communication by Extracellular Vesicles: Where We Are and Where We Need to Go

(2016) Mercedes Tkach et al.   CELL

Biological Activities of Extracellular Vesicles and Their Cargos from Bovine and Human Milk in Humans and Implications for Infants

(2016) Janos Zempleni et al.   JOURNAL OF NUTRITION

NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux

(2016) Yuan He et al.   NATURE

Experimental models of hepatotoxicity related to acute liver failure

(2016) Michaël Maes et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Mechanism and Regulation of NLRP3 Inflammasome Activation

(2016) Yuan He et al.   TRENDS IN BIOCHEMICAL SCIENCES

PER1 prevents excessive innate immune response during endotoxin-induced liver injury through regulation of macrophage recruitment in mice

(2016) T Wang et al.   Cell Death & Disease

A Genome-wide CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) Screen Identifies NEK7 as an Essential Component of NLRP3 Inflammasome Activation

(2015) Jonathan L. Schmid-Burgk et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Intestinal Transport of Bovine Milk Exosomes Is Mediated by Endocytosis in Human Colon Carcinoma Caco-2 Cells and Rat Small Intestinal IEC-6 Cells

(2015) Tovah Wolf et al.   JOURNAL OF NUTRITION

Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling

(2015) Nobuhiko Kayagaki et al.   NATURE

Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death

(2015) Jianjin Shi et al.   NATURE

NLRP3 activation and mitosis are mutually exclusive events coordinated by NEK7, a new inflammasome component

(2015) Hexin Shi et al.   NATURE IMMUNOLOGY

Inflammasomes: mechanism of action, role in disease and therapeutics

(2015) Haitao Guo et al.   NATURE MEDICINE

Interspecies communication between plant and mouse gut host cells through edible plant derived exosome-like nanoparticles

(2014) Jingyao Mu et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Inflammasome activation leads to Caspase-1-dependent mitochondrial damage and block of mitophagy

(2014) J. Yu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Innate Immune Receptors: Key Regulators of Metabolic Disease Progression

(2013) Chengcheng Jin et al.   Cell Metabolism

Determination of anti-inflammatory activities of standardised preparations of plant- and mushroom-based foods

(2013) Dhanushka Gunawardena et al.   EUROPEAN JOURNAL OF NUTRITION

NLRP3 inflammasome activation in d-galactosamine and lipopolysaccharide-induced acute liver failure: Role of heme oxygenase-1

(2013) Seok-Joo Kim et al.   FREE RADICAL BIOLOGY AND MEDICINE

Acute Liver Failure

(2013) William Bernal et al.   NEW ENGLAND JOURNAL OF MEDICINE

Delivery of therapeutic agents by nanoparticles made of grapefruit-derived lipids

(2013) Qilong Wang et al.   Nature Communications

Inflammasomes and Their Roles in Health and Disease

(2012) Mohamed Lamkanfi et al.   Annual Review of Cell and Developmental Biology

The Cancer Preventive Effects of Edible Mushrooms

(2012) Tongtong Xu et al.   Anti-Cancer Agents in Medicinal Chemistry

Critical role for calcium mobilization in activation of the NLRP3 inflammasome

(2012) T. Murakami et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA

(2009) Teresa Fernandes-Alnemri et al.   NATURE

AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

(2009) Veit Hornung et al.   NATURE

HIN-200 Proteins Regulate Caspase Activation in Response to Foreign Cytoplasmic DNA

(2009) T. L. Roberts et al.   SCIENCE