Near-infrared light driven tissue-penetrating cardiac optogenetics via upconversion nanoparticles in vivo

Near-Infrared-Light Activatable Nanoparticles for Deep-Tissue-Penetrating Wireless Optogenetics

(2019) Nuo Yu et al.   Advanced Healthcare Materials

Adeno-Associated Virus Mediated Gene Delivery: Implications for Scalable in vitro and in vivo Cardiac Optogenetic Models

(2019) Christina M. Ambrosi et al.   Frontiers in Physiology

An automated hybrid bioelectronic system for autogenous restoration of sinus rhythm in atrial fibrillation

(2019) Emile C. A. Nyns et al.   Science Translational Medicine

Optogenetic Termination of Cardiac Arrhythmia: Mechanistic Enlightenment and Therapeutic Application?

(2019) Philipp Sasse et al.   Frontiers in Physiology

Core–Shell–Shell Upconversion Nanoparticles with Enhanced Emission for Wireless Optogenetic Inhibition

(2018) Xudong Lin et al.   NANO LETTERS

Microscale optoelectronic infrared-to-visible upconversion devices and their use as injectable light sources

(2018) He Ding et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Near-infrared deep brain stimulation via upconversion nanoparticle–mediated optogenetics

(2018) Shuo Chen et al.   SCIENCE

Advances in highly doped upconversion nanoparticles

(2018) Shihui Wen et al.   Nature Communications

Graphene biointerfaces for optical stimulation of cells

(2018) Alex Savchenko et al.   Science Advances

Optical stimulation of cardiac cells with a polymer-supported silicon nanowire matrix

(2018) Ramya Parameswaran et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

P5838Local epicardial light pulse terminates ventricular arrhythmias in the adult rat heart upon optogenetic modification: towards biological shockless defibrillation

(2017) E.C.A. Nyns et al.   EUROPEAN HEART JOURNAL

Termination of re-entrant atrial tachycardia via optogenetic stimulation with optimized spatial targeting: insights from computational models

(2017) Patrick M. Boyle et al.   JOURNAL OF PHYSIOLOGY-LONDON

An infrared optical pacing system for screening cardiac electrophysiology in human cardiomyocytes

(2017) Matthew T. McPheeters et al.   PLoS One

Mechano-dependent signaling by Latrophilin/CIRL quenches cAMP in proprioceptive neurons

(2017) Nicole Scholz et al.   eLife

Optogenetic Control of Heart Rhythm by Selective Stimulation of Cardiomyocytes Derived from Pnmt+ Cells in Murine Heart

(2017) Yanwen Wang et al.   Scientific Reports

Optogenetic defibrillation terminates ventricular arrhythmia in mouse hearts and human simulations

(2016) Tobias Bruegmann et al.   JOURNAL OF CLINICAL INVESTIGATION

Opsin spectral sensitivity determines the effectiveness of optogenetic termination of ventricular fibrillation in the human heart: a simulation study

(2016) Thomas V. Karathanos et al.   JOURNAL OF PHYSIOLOGY-LONDON

Modulation of cardiomyocyte activity using pulsed laser irradiated gold nanoparticles

(2016) Lara Gentemann et al.   Biomedical Optics Express

Systemic gene transfer enables optogenetic pacing of mouse hearts

(2015) C. C. Vogt et al.   CARDIOVASCULAR RESEARCH

Optogenetics for in vivo cardiac pacing and resynchronization therapies

(2015) Udi Nussinovitch et al.   NATURE BIOTECHNOLOGY

Optogenetic determination of the myocardial requirements for extrasystoles by cell type-specific targeting of ChannelRhodopsin-2

(2015) Tania Zaglia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Modulation of cardiac tissue electrophysiological properties with light-sensitive proteins

(2014) Udi Nussinovitch et al.   CARDIOVASCULAR RESEARCH

Channelrhodopsin-2-XXL, a powerful optogenetic tool for low-light applications

(2014) A. Dawydow et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

3D multifunctional integumentary membranes for spatiotemporal cardiac measurements and stimulation across the entire epicardium

(2014) Lizhi Xu et al.   Nature Communications

Channelrhodopsin2 Current During the Action Potential: “Optical AP Clamp” and Approximation

(2014) Emilia Entcheva et al.   Scientific Reports

Nd3+-Sensitized Upconversion Nanophosphors: Efficient In Vivo Bioimaging Probes with Minimized Heating Effect

(2013) Ye-Fu Wang et al.   ACS Nano

ReaChR: a red-shifted variant of channelrhodopsin enables deep transcranial optogenetic excitation

(2013) John Y Lin et al.   NATURE NEUROSCIENCE

Optical pacing of the adult rabbit heart

(2013) Michael W. Jenkins et al.   Biomedical Optics Express

Computational Optogenetics: Empirically-Derived Voltage- and Light-Sensitive Channelrhodopsin-2 Model

(2013) John C. Williams et al.   PLoS Computational Biology

Multiscale Computational Models for Optogenetic Control of Cardiac Function

(2011) Oscar J. Abilez et al.   BIOPHYSICAL JOURNAL

Upconversion fluorescent nanoparticles as a potential tool for in-depth imaging

(2011) Sounderya Nagarajan et al.   NANOTECHNOLOGY

Principles for applying optogenetic tools derived from direct comparative analysis of microbial opsins

(2011) Joanna Mattis et al.   NATURE METHODS

Optogenetic control of heart muscle in vitro and in vivo

(2010) Tobias Bruegmann et al.   NATURE METHODS

Optical pacing of the embryonic heart

(2010) M. W. Jenkins et al.   Nature Photonics

Optogenetic Control of Cardiac Function

(2010) A. B. Arrenberg et al.   SCIENCE

Characterization of Engineered Channelrhodopsin Variants with Improved Properties and Kinetics

(2009) John Y. Lin et al.   BIOPHYSICAL JOURNAL

Assessment of Near-Infrared Path Length in Fibrous Phantom and Muscle Tissue

(2008) Eugene Gussakovsky et al.   APPLIED SPECTROSCOPY

A femtosecond laser pacemaker for heart muscle cells

(2008) N. I. Smith et al.   OPTICS EXPRESS