Autonomic ganglionic injection of α-synuclein fibrils as a model of pure autonomic failure α-synucleinopathy

Transneuronal Propagation of Pathologic α-Synuclein from the Gut to the Brain Models Parkinson’s Disease

(2019) Sangjune Kim et al.   NEURON

Neuropathology of autonomic dysfunction in synucleinopathies

(2018) Elizabeth A. Coon et al.   MOVEMENT DISORDERS

Is constipation in Parkinson's disease caused by gut or brain pathology?

(2018) Per Borghammer   PARKINSONISM & RELATED DISORDERS

Recent advances in neuropathology, biomarkers and therapeutic approach of multiple system atrophy

(2017) Shunsuke Koga et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

How does parkinson's disease begin? Perspectives on neuroanatomical pathways, prions, and histology

(2017) Per Borghammer   MOVEMENT DISORDERS

A new fate mapping system reveals context-dependent random or clonal expansion of microglia

(2017) Tuan Leng Tay et al.   NATURE NEUROSCIENCE

Enhanced interstitial fluid drainage in the hippocampus of spontaneously hypertensive rats

(2017) Beatrice Bedussi et al.   Scientific Reports

Pure Autonomic Failure

(2016) Pariwat Thaisetthawatkul   Current Neurology and Neuroscience Reports

Clinical neurocardiology defining the value of neuroscience-based cardiovascular therapeutics

(2016) Kalyanam Shivkumar et al.   JOURNAL OF PHYSIOLOGY-LONDON

Neuroinvasion of α-Synuclein Prionoids after Intraperitoneal and Intraglossal Inoculation

(2016) Sara Breid et al.   JOURNAL OF VIROLOGY

Induction of de novo α-synuclein fibrillization in a neuronal model for Parkinson’s disease

(2016) Mohamed-Bilal Fares et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Mouse Model of Heart Failure with Preserved Ejection Fraction due to Chronic Infusion of a Low Subpressor Dose of Angiotensin II

(2015) Jessica A Regan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Central mechanisms regulating coordinated cardiovascular and respiratory function during stress and arousal

(2015) Roger A. L. Dampney   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Structure, function and toxicity of alpha-synuclein: the Bermuda triangle in synucleinopathies

(2015) Anna Villar-Piqué et al.   JOURNAL OF NEUROCHEMISTRY

A cell culture model for monitoring α-synuclein cell-to-cell transfer

(2015) Juan F. Reyes et al.   NEUROBIOLOGY OF DISEASE

Prion-like propagation of human brain-derived alpha-synuclein in transgenic mice expressing human wild-type alpha-synuclein

(2015) Maria E. Bernis et al.   Acta Neuropathologica Communications

Olfactory Dysfunction and Neurotransmitter Disturbance in Olfactory Bulb of Transgenic Mice Expressing Human A53T Mutant α-Synuclein

(2015) Sufang Zhang et al.   PLoS One

A mouse renin distal enhancer is essential for blood pressure homeostasis in BAC-rescuedrenin-null mutant mice

(2014) Keiji Tanimoto et al.   JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION

Component analysis of Pu-erh and its anti-constipation effects

(2014) GUIJIE LI et al.   Molecular Medicine Reports

Intracellular processing of disease-associated α-synuclein in the human brain suggests prion-like cell-to-cell spread

(2014) Gabor G. Kovacs et al.   NEUROBIOLOGY OF DISEASE

Intramuscular injection of  -synuclein induces CNS  -synuclein pathology and a rapid-onset motor phenotype in transgenic mice

(2014) A. N. Sacino et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glucocerebrosidase depletion enhances cell-to-cell transmission of α-synuclein

(2014) Eun-Jin Bae et al.   Nature Communications

Pathological alpha-synuclein propagates through neural networks

(2014) Masami Masuda-Suzukake et al.   Acta Neuropathologica Communications

Transfer of human α-synuclein from the olfactory bulb to interconnected brain regions in mice

(2013) Nolwen L. Rey et al.   ACTA NEUROPATHOLOGICA

Prion-like spreading of pathological α-synuclein in brain

(2013) Masami Masuda-Suzukake et al.   BRAIN

Vanadium exposure induces olfactory dysfunction in an animal model of metal neurotoxicity

(2013) Hilary Afeseh Ngwa et al.   NEUROTOXICOLOGY

α-Synucleinopathy phenotypes

(2013) Heather McCann et al.   PARKINSONISM & RELATED DISORDERS

Olfaction in Three Genetic and Two MPTP-Induced Parkinson’s Disease Mouse Models

(2013) Stefan Kurtenbach et al.   PLoS One

Transmission of multiple system atrophy prions to transgenic mice

(2013) J. C. Watts et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intracerebral inoculation of pathological α-synuclein initiates a rapidly progressive neurodegenerative α-synucleinopathy in mice

(2012) Kelvin C. Luk et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Pathological  -Synuclein Transmission Initiates Parkinson-like Neurodegeneration in Nontransgenic Mice

(2012) K. C. Luk et al.   SCIENCE

Autonomic dysfunction and plasticity in micturition reflexes in human α-synuclein mice

(2011) Robert W. Hamill et al.   Developmental Neurobiology

Prion-like acceleration of a synucleinopathy in a transgenic mouse model

(2011) Anne-Laure Mougenot et al.   NEUROBIOLOGY OF AGING

Exogenous α-Synuclein Fibrils Induce Lewy Body Pathology Leading to Synaptic Dysfunction and Neuron Death

(2011) Laura A. Volpicelli-Daley et al.   NEURON

Olfactory dysfunction in pure autonomic failure: Implications for the pathogenesis of Lewy body diseases

(2009) David S. Goldstein et al.   PARKINSONISM & RELATED DISORDERS

Inclusion formation and neuronal cell death through neuron-to-neuron transmission of  -synuclein

(2009) P. Desplats et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Local circuit input to the medullary reticular formation from the rostral nucleus of the solitary tract

(2008) J. Nasse et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Central dopamine deficiency in pure autonomic failure

(2008) David S. Goldstein et al.   CLINICAL AUTONOMIC RESEARCH

Potential clinical relevance of the ‘little brain’ on the mammalian heart

(2007) J. A. Armour   EXPERIMENTAL PHYSIOLOGY