β4GALT1 controls β1 integrin function to govern thrombopoiesis and hematopoietic stem cell homeostasis

Galactosyl carbohydrate residues on hematopoietic stem/progenitor cells are essential for homing and engraftment to the bone marrow

(2019) Soichiro Takagaki et al.   Scientific Reports

Turbulence Activates Platelet Biogenesis to Enable Clinical Scale Ex Vivo Production

(2018) Yukitaka Ito et al.   CELL

Lineage-Biased Hematopoietic Stem Cells Are Regulated by Distinct Niches

(2018) Sandra Pinho et al.   DEVELOPMENTAL CELL

Clonal analysis of lineage fate in native haematopoiesis

(2018) Alejo E. Rodriguez-Fraticelli et al.   NATURE

Inherited thrombocytopenia associated with mutation of UDP-Galactose-4-Epimerase (GALE)

(2018) Aaron Seo et al.   HUMAN MOLECULAR GENETICS

The importance of N-glycosylation on β3 integrin ligand binding and conformational regulation

(2017) Xiulei Cai et al.   Scientific Reports

Inflammation-Induced Emergency Megakaryopoiesis Driven by Hematopoietic Stem Cell-like Megakaryocyte Progenitors

(2015) Simon Haas et al.   Cell Stem Cell

Cytoskeletal perturbation leads to platelet dysfunction and thrombocytopenia in variant forms of Glanzmann thrombasthenia

(2015) L. Bury et al.   HAEMATOLOGICA

Multifaceted roles of 5′-regulatory region of the cancer associated gene B4GALT1 and its comparison with the gene family

(2015) MOHAMMED A. IBRAHIM AL-OBAIDE et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Cytoskeletal perturbation leads to platelet dysfunction and thrombocytopenia in variant forms of Glanzmann thrombasthenia

(2015) L. Bury et al.   HAEMATOLOGICA

SDF-1 dynamically mediates megakaryocyte niche occupancy and thrombopoiesis at steady state and following radiation injury

(2014) L. M. Niswander et al.   BLOOD

β-1,4-Galactosyltransferase III suppresses β1 integrin-mediated invasive phenotypes and negatively correlates with metastasis in colorectal cancer

(2014) Chia-Hua Chen et al.   CARCINOGENESIS

Glycosylation of the laminin receptor (α3β1) regulates its association with tetraspanin CD151: Impact on cell spreading, motility, degradation and invasion of basement membrane by tumor cells

(2014) Amit Ranjan et al.   EXPERIMENTAL CELL RESEARCH

A promoter-level mammalian expression atlas

(2014)   NATURE

Megakaryocytes maintain homeostatic quiescence and promote post-injury regeneration of hematopoietic stem cells

(2014) Meng Zhao et al.   NATURE MEDICINE

Megakaryocytes regulate hematopoietic stem cell quiescence through CXCL4 secretion

(2014) Ingmar Bruns et al.   NATURE MEDICINE

The Ashwell-Morell receptor regulates hepatic thrombopoietin production via JAK2-STAT3 signaling

(2014) Renata Grozovsky et al.   NATURE MEDICINE

GNE myopathy associated with congenital thrombocytopenia: A report of two siblings

(2014) Rumiko Izumi et al.   NEUROMUSCULAR DISORDERS

C1GALT1 Promotes Invasive Phenotypes of Hepatocellular Carcinoma Cells by Modulating Integrin β1 Glycosylation and Activity

(2014) Chiung-Hui Liu et al.   PLoS One

CD41 expression marks myeloid-biased adult hematopoietic stem cells and increases with age

(2013) C. Gekas et al.   BLOOD

Biogenesis of the demarcation membrane system (DMS) in megakaryocytes

(2013) A. Eckly et al.   BLOOD

 1 integrin-mediated signals are required for platelet granule secretion and hemostasis in mouse

(2013) T. Petzold et al.   BLOOD

Integrin α 6 β 1 Is the Main Receptor for Vascular Laminins and Plays a Role in Platelet Adhesion, Activation, and Arterial Thrombosis

(2013) Mathieu Schaff et al.   CIRCULATION

Expression of integrins α3β1 and α5β1 and GlcNAc β1,6 glycan branching influences metastatic melanoma cell migration on fibronectin

(2013) Ewa Pocheć et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Transcription factors in late megakaryopoiesis and related platelet disorders

(2013) M. R. Tijssen et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Platelet-biased stem cells reside at the apex of the haematopoietic stem-cell hierarchy

(2013) Alejandra Sanjuan-Pla et al.   NATURE

Demonstration of novel gain-of-function mutations of αIIbβ3: association with macrothrombocytopenia and glanzmann thrombasthenia-like phenotype

(2013) Hirokazu Kashiwagi et al.   Molecular Genetics & Genomic Medicine

Outside-In Signalling Generated by a Constitutively Activated Integrin αIIbβ3 Impairs Proplatelet Formation in Human Megakaryocytes

(2012) Loredana Bury et al.   PLoS One

Regulation of the  1,4-Galactosyltransferase I promoter by E2F1

(2010) Y. Wei et al.   JOURNAL OF BIOCHEMISTRY

Cytoskeletal mechanics of proplatelet maturation and platelet release

(2010) Jonathan N. Thon et al.   JOURNAL OF CELL BIOLOGY

Importance of N-Glycosylation on α5β1 Integrin for Its Biological Functions

(2009) Jianguo Gu et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Bisecting GlcNAc Residues on Laminin-332 Down-regulate Galectin-3-dependent Keratinocyte Motility

(2009) Yoshinobu Kariya et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Learning/Memory Impairment and Reduced Expression of the HNK-1 Carbohydrate in β4-Galactosyltransferase-II-deficient Mice

(2009) Toru Yoshihara et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dual roles for hepatic lectin receptors in the clearance of chilled platelets

(2009) Viktoria Rumjantseva et al.   NATURE MEDICINE

Structure and Function of β -1,4-Galactosyltransferase

(2008) Pradman Qasba et al.   CURRENT DRUG TARGETS

ST6Gal-I expression in ovarian cancer cells promotes an invasive phenotype by altering integrin glycosylation and function

(2008) Daniel R Christie et al.   Journal of Ovarian Research