Arc silence aggravates traumatic neuronal injury via mGluR1-mediated ER stress and necroptosis

Traumatic brain injury in China

(2019) Ji-Yao Jiang et al.   LANCET NEUROLOGY

Vitamin B12 Enhances Nerve Repair and Improves Functional Recovery After Traumatic Brain Injury by Inhibiting ER Stress-Induced Neuron Injury

(2019) Fangfang Wu et al.   Frontiers in Pharmacology

2-BFI Provides Neuroprotection Against Inflammation and Necroptosis in a Rat Model of Traumatic Brain Injury

(2019) Haibo Ni et al.   Frontiers in Neuroscience

Microglia-targeted candidates push the Alzheimer drug envelope

(2018) Asher Mullard   NATURE REVIEWS DRUG DISCOVERY

Transcriptional and post-translational regulation of Arc in synaptic plasticity

(2018) Ruth E. Carmichael et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Roles for Arc in metabotropic glutamate receptor-dependent LTD and synapse elimination: Implications in health and disease

(2018) Julia R. Wilkerson et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Ferroptosis Contributes to Neuronal Death and Functional Outcome After Traumatic Brain Injury

(2018) Elizabeth M. Kenny et al.   CRITICAL CARE MEDICINE

Necroptosis and RIPK1-mediated neuroinflammation in CNS diseases

(2018) Junying Yuan et al.   NATURE REVIEWS NEUROSCIENCE

Variation in Adult Traumatic Brain Injury Outcomes in the United States

(2017) Nathaniel H. Greene et al.   JOURNAL OF HEAD TRAUMA REHABILITATION

Glutamate-induced rapid induction of Arc/Arg3.1 requires NMDA receptor-mediated phosphorylation of ERK and CREB

(2017) Tao Chen et al.   NEUROSCIENCE LETTERS

Therapeutic hypothermia attenuates tissue damage and cytokine expression after traumatic brain injury by inhibiting necroptosis in the rat

(2016) Tao Liu et al.   Scientific Reports

Downregulation of STIM2 improves neuronal survival after traumatic brain injury by alleviating calcium overload and mitochondrial dysfunction

(2015) Wei Rao et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Docosahexaenoic Acid Reduces ER Stress and Abnormal Protein Accumulation and Improves Neuronal Function Following Traumatic Brain Injury

(2014) G. Begum et al.   JOURNAL OF NEUROSCIENCE

Postsynaptic scaffold protein Homer 1a protects against traumatic brain injury via regulating group I metabotropic glutamate receptors

(2014) P Luo et al.   Cell Death & Disease

ER stress-induced cell death mechanisms

(2013) Renata Sano et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Stressed to death – mechanisms of ER stress-induced cell death

(2013) Natalia Sovolyova et al.   BIOLOGICAL CHEMISTRY

Downregulation of postsynaptic density-95-interacting regulator of spine morphogenesis reduces glutamate-induced excitotoxicity by differentially regulating glutamate receptors in rat cortical neurons

(2013) Peng Luo et al.   FEBS Journal

Curcumin protects against iron induced neurotoxicity in primary cortical neurons by attenuating necroptosis

(2013) Min-chao Dai et al.   NEUROSCIENCE LETTERS

Protective effect of Homer 1a on tumor necrosis factor-α with cycloheximide-induced apoptosis is mediated by mitogen-activated protein kinase pathways

(2012) Peng Luo et al.   APOPTOSIS

Protective effect of Homer 1a against hydrogen peroxide-induced oxidative stress in PC12 cells

(2012) Peng Luo et al.   FREE RADICAL RESEARCH

Pre- and post-synaptic cortical cholinergic deficits are proportional to amyloid plaque presence and density at preclinical stages of Alzheimer’s disease

(2011) Pamela E. Potter et al.   ACTA NEUROPATHOLOGICA

The role of glutamate receptors in traumatic brain injury: Implications for postsynaptic density in pathophysiology

(2011) Peng Luo et al.   BRAIN RESEARCH BULLETIN

Down-regulation of Homer1b/c attenuates glutamate-mediated excitotoxicity through endoplasmic reticulum and mitochondria pathways in rat cortical neurons

(2011) Tao Chen et al.   FREE RADICAL BIOLOGY AND MEDICINE

Endoplasmic reticulum protein BI-1 modulates unfolded protein response signaling and protects against stroke and traumatic brain injury

(2010) Maryla Krajewska et al.   BRAIN RESEARCH

Cell death mechanisms and modulation in traumatic brain injury

(2010) Bogdan A. Stoica et al.   Neurotherapeutics

Protein translation in synaptic plasticity: mGluR-LTD, Fragile X

(2009) Maggie W Waung et al.   CURRENT OPINION IN NEUROBIOLOGY

Necrostatin-1 Reduces Histopathology and Improves Functional Outcome after Controlled Cortical Impact in Mice

(2008) Zerong You et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

The Immediate Early Gene Arc/Arg3.1: Regulation, Mechanisms, and Function

(2008) C. R. Bramham et al.   JOURNAL OF NEUROSCIENCE

Rapid Translation of Arc/Arg3.1 Selectively Mediates mGluR-Dependent LTD through Persistent Increases in AMPAR Endocytosis Rate

(2008) Maggie W. Waung et al.   NEURON

Necroptosis contributes to the NMDA-induced excitotoxicity in rat’s cultured cortical neurons

(2008) Yanli Li et al.   NEUROSCIENCE LETTERS