Article
Pharmacology & Pharmacy
Abdullah A. Alarfaj, Abdurahman Hajinur Hirad, Balasubramani Ravindran, Shilpa Perumal Narasimhamoorthi
Summary: This study successfully synthesized stable copper oxide nanoparticles using Aegle marmelos leaf extract and investigated their structural and antibacterial potential. The synthesized nanoparticles showed excellent antibacterial activity against Escherichia coli and Shigella flexneri, and complete plasmid DNA fragmentation was observed at higher concentration. Furthermore, in silico analysis confirmed the binding and interaction of active molecules in Aegle marmelos leaf extract with the BAM A transmembrane protein, suggesting their potential as drug candidates.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
(2023)
Article
Pharmacology & Pharmacy
Divya Tharani Sukumar, Gayathiri Gunasangkaran, Vijaya Anand Arumugam, Saradhadevi Muthukrishnan
Summary: This study successfully synthesized chitosan encapsulated Aegle marmelos silver nanoparticles (CEAMAgNp) using a green synthesis method. The nanoparticles were characterized using various techniques. The results showed that CEAMAgNp exhibited anticancer activity and acted through the EMT pathway.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
(2022)
Article
Nanoscience & Nanotechnology
M. S. Roshni Priya, R. Subashini, P. Senthil Kumar, A. Deepadharshini, M. Monisaah Sree, K. Murugan, M. Sumathi
Summary: This study evaluated the phytochemical components and antioxidant activity of Aegle marmelos (L.) fruit extract, as well as the antibacterial effect of silver nanoparticles synthesized from the extract. The results showed that A. marmelos (L.) is rich in bioactive compounds and has potential antioxidant activity. The bioactive silver nanoparticles exhibited strong antibacterial activity against various pathogens.
APPLIED NANOSCIENCE
(2022)
Article
Biochemistry & Molecular Biology
Nishal M. Egodawaththa, Amy L. Knight, Jingxuan Ma, D. Andrew Knight, Eric Guisbert, Nasri Nesnas
Summary: Silver nanoparticles conjugated with organic ligands have been successfully synthesized and demonstrated significant antimicrobial activity and antibacterial capabilities against E. coli. The synthesis of functionalized silver nanoparticles is critical for the further development of silver-nanoconjugated antibacterial agents.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Chemistry, Multidisciplinary
Fatma Abdelghaffar, Manal G. Mahmoud, Mohsen S. Asker, Sahar S. Mohamed
Summary: This study successfully deposited antibacterial silver nanoparticles on linen fabrics using a green synthesis method; optimization of AgNPs synthesis conditions led to smaller particle sizes; the results demonstrated that BSEPS/AgNPs played a dual role in reducing bacterial activity and increasing dyeability.
JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY
(2021)
Article
Multidisciplinary Sciences
P. Rama, P. Mariselvi, R. Sundaram, K. Muthu
Summary: The present study synthesized silver nanoparticles (Ag NPs) using a green method with Aegle marmelos leaf extract as the reducing and capping agents. UV-vis spectrophotometry confirmed the formation of Ag NPs, and phytochemical and FT-IR analysis indicated the presence of flavonoids as the reducing and capping agents. Transmission electron microscopy revealed spherical Ag NPs with a size range of approximately 30-50 nm. The synthesized Ag NPs exhibited potential anticancer, antimicrobial, and antioxidant activity, and showed cytotoxicity against MDA-MB-231 breast cancer cells. Additionally, Ag NPs acted as an excellent photocatalyst for the degradation of Basic Fuchsin dye within 18 minutes.
Article
Environmental Sciences
Xiang Xiao, En-Jing He, Xue-Rong Lu, Li-Jun Wu, Yang-Yang Fan, Han-Qing Yu
Summary: The study shows that silver nanoparticles possess strong antibacterial ability, leading to the majority of bacteria entering a viable but non-culturable state. Environmental factors such as Cl- and illumination can affect the solubility of nanoparticles and thereby impact the survival state of bacteria.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Chemistry, Inorganic & Nuclear
Anindita De, Preeti Jain, Amit Kumar Manna, Vivek Srivastava, Riya Das
Summary: This study successfully synthesized silver nanoparticles (B-AgNPs) using bark extract of Aegle marmelos L. in aqueous medium, characterized them, and explored their biological applications. The B-AgNPs exhibited significant DNA cleavage activity, antibacterial potential against various strains, and antioxidant properties.
INORGANIC AND NANO-METAL CHEMISTRY
(2021)
Article
Biochemistry & Molecular Biology
Maryam Bayat, Meisam Zargar, Elena Chudinova, Tamara Astarkhanova, Elena Pakina
Summary: Metallic nanoparticles are receiving increased attention due to their wide use in agriculture and biotechnology. Environmentally friendly strategies for synthesizing nanoparticles, such as biological practices, are gaining interest as eco-friendly alternatives to chemical synthesis in order to minimize the impact on the environment. This study shows that biogenic silver nanoparticles are more effective antimicrobial agents compared to copper nanoparticles, providing promising preliminary data for their potential use in managing different pathogens.
Review
Chemistry, Multidisciplinary
Sumera Zaib, Hira Javed, Hanan A. Ogaly, Imtiaz Khan
Summary: Gastric ulcer is a common gastrointestinal disorder that affects about 10% of the world population. Synthetic drugs used for prevention have harmful effects, thus there is a need for improved drug candidates with minimal toxicity. Aegle marmelos, with its proven antibacterial and antiulcer properties, presents a promising herbal remedy for gastric ulcers caused by Helicobacter pylori infections and nonsteroidal anti-inflammatory drugs. It exerts its effects through inhibiting secretory factors and activating antioxidant processes.
Article
Food Science & Technology
Endang Susilowati, Lina Mahardiani, Retno Duwi Hardini
Summary: Silver-alginate nanocomposite films with antibacterial properties were prepared using the casting method. The properties of the films were characterized through various tests. The presence of silver nanoparticles affected the mechanical properties and crystallinity of the films, which also exhibited a rough and porous structure. The nanocomposite films showed antibacterial activity against different bacteria, and the activity was dependent on the concentration of silver nanoparticles.
FRONTIERS IN SUSTAINABLE FOOD SYSTEMS
(2022)
Article
Biology
Roua Alsubki, Hajera Tabassum, Manal Abudawood, Ali A. Rabaan, Sarah F. Alsobaie, Sabah Ansar
Summary: The study focused on the green synthesis of silver nanoparticles from Coriander sativum, which demonstrated strong antimicrobial and antioxidant activities, as well as significant anticancer effects on cancerous cells.
SAUDI JOURNAL OF BIOLOGICAL SCIENCES
(2021)
Article
Chemistry, Multidisciplinary
Tairong Kuang, Linbing Deng, Sitao Shen, Hongxia Deng, Zhisen Shen, Zhenjie Liu, Zhengping Zhao, Feng Chen, Mingqiang Zhong
Summary: Drug-resistant bacteria pose a serious threat to public health, highlighting the need for broad-spectrum antibacterial agents that do not cause drug resistance. In this study, different morphologies of nano-silver-modified polyphosphazene nanoparticles were synthesized and characterized. The results showed that the antibacterial activity of silver nanoparticles varies depending on their immobilized form, with stronger bactericidal effects on Gram-positive bacteria.
CHINESE CHEMICAL LETTERS
(2023)
Article
Nanoscience & Nanotechnology
Fangke Lin, Qianqian Qi, Junle Zhang, Wenjun Zhou, Jiahui Zhang, Peng Fu, Xiaomeng Zhang, Xiaoguang Qiao, Minying Liu, Xinchang Pang, Zhe Cui
Summary: Silver nanomaterials have shown broad-spectrum antimicrobial activity, with the challenge of balancing high antibacterial efficiency and low damage to biological cells. A new type of Ag nanohybrid material was developed using a unimolecular micelle template method, demonstrating excellent antibacterial activities and almost no cytotoxicity. This structure successfully addresses the reactivity, instability, and fast oxidation issues of ultrasmall silver nanoparticles, integrating high antibacterial efficiency and nontoxicity into one platform for potential biomedical applications.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Biotechnology & Applied Microbiology
Morteza Yadi, Mehdi Azizi, Hassan Dianat-Moghadam, Abolfazl Akbarzadeh, Morteza Abyadeh, Morteza Milani
Summary: Recent studies have shown that the synthesis of gold (Au) and silver (Ag) nanoparticles through a biological process enhances their speed of synthesis, biocompatibility, and antimicrobial activity. In this study, Au- and Ag-based nanoparticles were synthesized using aqueous Ginger root extract and characterized using spectroscopic methods. The nanoparticles had hexagonal and spherical shapes, with average particle sizes of 20 nm for Au and 15 nm for Ag. The synthesized nanoparticles showed significant activity against Staphylococcus aureus and Escherichia coli, with low IC50 and IC90 values.
BIOPROCESS AND BIOSYSTEMS ENGINEERING
(2022)
Article
Microbiology
S. Durairaju Nisshanthini, Antony K. Teresa S. Infanta, Duraisamy Senthil Raja, Karuppannan Natarajan, M. Palaniswamy, Jayaraman Angayarkanni
JOURNAL OF MICROBIOLOGY
(2015)
Article
Biochemistry & Molecular Biology
F. Stanly Pradeep, M. Palaniswamy, S. Ravi, A. Thangamani, B. V. Pradeep
PROCESS BIOCHEMISTRY
(2015)
Review
Biotechnology & Applied Microbiology
Kalarikkal Gopikrishnan Kiran, Muthusamy Palaniswamy, Jayaraman Angayarkanni
WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY
(2015)
Review
Biotechnology & Applied Microbiology
Angayarkanni Jayaraman, Murugesan Thandeeswaran, Ulaganathan Priyadarsini, Shanmugam Sabarathinam, K. A. Ayub Nawaz, Muthusamy Palaniswamy
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
(2016)
Article
Biotechnology & Applied Microbiology
K. G. Kiran, M. Thandeeswaran, K. A. Ayub Nawaz, M. Easwaran, K. K. Jayagopi, L. Ebrahimi, M. Palaniswamy, R. Mahendran, J. Angayarkanni
JOURNAL OF APPLIED MICROBIOLOGY
(2016)
Article
Microbiology
Sourav Bhattacharya, Arijit Das, Muthusamy Palaniswamy, Jayaraman Angayarkanni
JOURNAL OF BASIC MICROBIOLOGY
(2017)
Article
Plant Sciences
K. A. Ayub Nawaz, Swapna Merlin David, Easwaran Murugesh, Murugesan Thandeeswaran, Kalarikkal Gopikrishnan Kiran, Ramasamy Mahendran, Muthusamy Palaniswamy, Jayaraman Angayarkanni
Article
Biochemistry & Molecular Biology
Thandeeswaran Murugesan, Karuppuswamy Velliayadevar, Murugesh Easwaran, K. G. Kiran, Ayub K. A. Nawaz, Mahendran Ramasamy, Palaniswamy Muthusamy, Angayarkanni Jayaraman
Article
Biochemistry & Molecular Biology
B. Vidya, M. Palaniswamy, J. Angayarkanni, Ayub K. Nawaz, M. Thandeeswaran, Krishna K. Chaithanya, Berihu Tekluu, Karthi Muthusamy, V. K. Gopalakrishnan
BIOORGANIC CHEMISTRY
(2020)
Article
Biochemistry & Molecular Biology
Anand Raj Dhanapal, Murugesan Thandeeswaran, Palaniswamy Muthusamy, Angayarkanni Jayaraman
Summary: This study revealed the importance of identification and purification of pterin deaminase from Agrobacterium tumefaciens LBA4404 for the first time. The enzyme shows potential as an anticancer agent.
BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY
(2023)
Proceedings Paper
Agriculture, Multidisciplinary
M. Thandeeswaran, P. Karthika, R. Mahendran, M. Palaniswamy, J. Angayarkanni
INTERNATIONAL CONFERENCE ON GREEN AGRO-INDUSTRY AND BIOECONOMY (ICGAB 2017)
(2018)
Article
Multidisciplinary Sciences
Shilpi Bhardwaj, Sourav Bhattacharya, Arijit Das, Muthusamy Palaniswamy, Jayaraman Angayarkanni
ARABIAN JOURNAL FOR SCIENCE AND ENGINEERING
(2017)
Article
Oceanography
R. Baskaran, P. M. Mohan, M. G. Madanan, Ashok Kumar, M. Palaniswami
INDIAN JOURNAL OF GEO-MARINE SCIENCES
(2015)
Review
Biotechnology & Applied Microbiology
Thandeeswaran Murugesan, Nisshanthini Durairaj, Mahendran Ramasamy, Karunya Jayaraman, Muthusamy Palaniswamy, Angayarkanni Jayaraman
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
(2018)