Wogonin glucuronidation in liver and intestinal microsomes of humans, monkeys, dogs, rats, and mice

Quantitative Analysis of UDP-Glucuronosyltransferase Ugt1a and Ugt2b mRNA Expression in the Rat Liver and Small Intestine: Sex and Strain Differences

(2018) Takaya Kutsukake et al.   DRUG METABOLISM AND DISPOSITION

Oral pharmacokinetics of baicalin, wogonoside, oroxylin A 7- O -β- d -glucuronide and their aglycones from an aqueous extract of Scutellariae Radix in the rat

(2016) Yu Cai et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Characterization and Bioavailability of Wogonin by Different Administration Routes in Beagles

(2016) Na Zhu et al.   MEDICAL SCIENCE MONITOR

Anti-inflammatory Effects of Baicalin, Baicalein, and Wogonin In Vitro and In Vivo

(2014) Wonhwa Lee et al.   INFLAMMATION

Development of a SPE-LC/MS/MS method for simultaneous quantification of baicalein, wogonin, oroxylin A and their glucuronides baicalin, wogonoside and oroxyloside in rats and its application to brain uptake and plasma pharmacokinetic studies

(2014) Sophia Yui Kau Fong et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Pharmacokinetics, Tissue Distribution, Excretion and Plasma Protein Binding Studies of Wogonin in Rats

(2014) Amer Talbi et al.   MOLECULES

Simultaneous determination of baicalin, wogonoside, baicalein, wogonin, oroxylin A and chrysin of Radix scutellariae extract in rat plasma by liquid chromatography tandem mass spectrometry

(2012) Ling Tong et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

A Novel Local Recycling Mechanism That Enhances Enteric Bioavailability of Flavonoids and Prolongs Their Residence Time in the Gut

(2012) Bijun Xia et al.   MOLECULAR PHARMACEUTICS

Comparison of Intestinal Absorption and Disposition of Structurally Similar Bioactive Flavones in Radix Scutellariae

(2011) Chenrui Li et al.   AAPS Journal

Quantification of Human Uridine-Diphosphate Glucuronosyl Transferase 1A Isoforms in Liver, Intestine, and Kidney Using Nanobore Liquid Chromatography–Tandem Mass Spectrometry

(2011) David E. Harbourt et al.   ANALYTICAL CHEMISTRY

Pharmacological effects and pharmacokinetics properties of Radix Scutellariae and its bioactive flavones

(2011) Chenrui Li et al.   BIOPHARMACEUTICS & DRUG DISPOSITION

The ethanol extract of Scutellaria baicalensis and the active compounds induce cell cycle arrest and apoptosis including upregulation of p53 and Bax in human lung cancer cells

(2011) Jiayu Gao et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Identification and quantification of baicalein, wogonin, oroxylin A and their major glucuronide conjugated metabolites in rat plasma after oral administration of Radix scutellariae product

(2010) Chenrui Li et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Structure-metabolism relationships for the glucuronidation of flavonoids by UGT1A3 and UGT1A9

(2010) Shenggu Xie et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Use of Isoform-Specific UGT Metabolism to Determine and Describe Rates and Profiles of Glucuronidation of Wogonin and Oroxylin A by Human Liver and Intestinal Microsomes

(2010) Qiong Zhou et al.   PHARMACEUTICAL RESEARCH

Flavonoid Pharmacokinetics and Tissue Distribution after Repeated Dosing of the Roots ofScutellaria baicalensisin Rats

(2010) Yu-Chi Hou et al.   PLANTA MEDICA

New therapeutic aspects of flavones: The anticancer properties of Scutellaria and its main active constituents Wogonin, Baicalein and Baicalin

(2008) Min Li-Weber   CANCER TREATMENT REVIEWS

Determination of mRNA Expression of Human UDP-Glucuronosyltransferases and Application for Localization in Various Human Tissues by Real-Time Reverse Transcriptase-Polymerase Chain Reaction

(2008) S. Ohno et al.   DRUG METABOLISM AND DISPOSITION