Article
Multidisciplinary Sciences
Cornelia Betsch, Philipp Schmid, Pierre Verger, Stephan Lewandowsky, Anna Soveri, Ralph Hertwig, Angelo Fasce, Dawn Holford, Paul De Raeve, Arnaud Gagneur, Pia Vuolanto, Tiago Correia, Lara Tavoschi, Silvia Declich, Maurizio Marceca, Athena Linos, Pania Karnaki, Linda Karlsson, Amanda Garrison
Summary: This article summarises the current challenges of routine vaccine uptake during the COVID-19 pandemic and provides recommendations to increase uptake. It also points out evidence-based resources to support healthcare workers, policy makers, and communicators.
NATURE COMMUNICATIONS
(2022)
Article
Cardiac & Cardiovascular Systems
Islam Y. Elgendy, Syed Bukhari, Amr F. Barakat, Carl J. Pepine, Kathryn J. Lindley, Eliza C. Miller
Summary: Maternal mortality rates in the US have been rising steadily, with cardiovascular mortality being the leading cause of death among pregnant and postpartum women. Maternal stroke contributes significantly to cardiovascular mortality, with rates of stroke among pregnant women increasing in recent years. Factors such as advancing maternal age, the increasing prevalence of traditional cardiovascular risk factors, and other risk factors like hypertensive disorders of pregnancy, migraine, and infections, may be contributing to the rising rates of maternal stroke.
Letter
Pediatrics
Sarah Hashim Mohammed Osman, Abdulqadir J. Nashwan
Summary: The ongoing conflict in Sudan has created a humanitarian crisis that greatly endangers the health and well-being of the country's children. This paper examines necessary policy interventions to protect child mental health services in these challenging circumstances. Essential strategies include improving healthcare accessibility, promoting education, enhancing living conditions, providing information on nutritious food, strengthening health systems, cooperating with international aid organizations, and partnering with local NGOs and humanitarian organizations. These comprehensive measures aim to mitigate the detrimental impacts of the conflict on Sudan's vulnerable children.
CHILD AND ADOLESCENT PSYCHIATRY AND MENTAL HEALTH
(2023)
Article
Gastroenterology & Hepatology
Fasiha Kanwal, Jay H. Shubrook, Zobair Younossi, Yamini Natarajan, Elisabetta Bugianesi, Mary E. Rinella, Stephen A. Harrison, Christos Mantzoros, Kim Pfotenhauer, Samuel Klein, Robert H. Eckel, Davida Kruger, Hashem El-Serag, Kenneth Cusi
Summary: There are significant management gaps between clinical guidelines and practice in patients with NAFLD and NASH, and there is no single global guiding strategy for their management. An international conference convened experts in gastroenterology, hepatology, endocrinology, and primary care providers to discuss promising approaches for clinical practice and prepare a comprehensive, unified strategy for the care of NAFLD/NASH patients. Participants also identified specific high-yield targets for clinical research and called for a unified, international public health response to NAFLD and NASH.
Letter
Public, Environmental & Occupational Health
Melona C. Deguma, Jabin J. Deguma
Summary: The pandemic caused a regressive effect on the global economy, leading to a 'de-globalized' process that has negatively impacted industries reliant on tourism, urban passenger transport services, and civil aviation. Urgent measures are needed to support vulnerable industries that are not resilient to the pandemic in order to aid economic recovery. The issue of falsifying Covid-19 diagnostic testing certification poses a significant problem in terms of ethics and economics, especially with the start of vaccination programs against Covid-19. This paper argues that collective efforts from everyone could lead to a new normal world that is immune to viruses and unethical behaviors.
JOURNAL OF PUBLIC HEALTH
(2021)
Review
Endocrinology & Metabolism
Fasiha Kanwal, Jay H. Shubrook, Zobair Younossi, Yamini Natarajan, Elisabetta Bugianesi, Mary E. Rinella, Stephen A. Harrison, Christos Mantzoros, Kim Pfotenhauer, Samuel Klein, Robert H. Eckel, Davida Kruger, Hashem El-Serag, Kenneth Cusi
Summary: NAFLD and NASH are common conditions with a rising burden, but there are significant gaps between clinical guidelines and practice in managing these diseases. An international conference of experts from various countries was convened to discuss global burden, screening, risk stratification, diagnosis, and management, leading to the development of a comprehensive unified strategy for care.
Article
Immunology
Ramy Mohamed Ghazy, Saja Yazbek, Assem Gebreal, Mai Hussein, Sylvia Agyeman Addai, Ernestina Mensah, Michael Sarfo, Agyapong Kofi, Tareq AL-Ahdal, Gilbert Eshun
Summary: This study aimed to assess the intention to receive the monkeypox vaccine among the Ghanaian population and identified low levels of willingness to accept the vaccine. Non-healthcare workers had lower vaccine acceptance compared to healthcare workers. The determinants of vaccine acceptance included male gender, urban residence, refusal of the COVID-19 vaccine, confidence in vaccination, and collective responsibility. Tailoring efforts to promote monkeypox vaccination, especially among non-healthcare workers, is necessary by increasing their confidence in vaccine effectiveness and safety and promoting the importance of self-vaccination to protect others.
Article
Oncology
Eline M. Bunnik, Wybo J. Dondorp, Annelien L. Bredenoord, Guido de Wert, Martina C. Cornel
Summary: The wider availability of genomic sequencing in cancer care allows for personalized medicine based on genetic characteristics. Genomic testing may yield various results beyond therapy-focused answers, such as germline mutations and variants of uncertain significance. Consent practices for genomic sequencing in mainstream cancer care should focus on preparing patients for unsolicited outcomes and may not require opt-out options when the chance of such findings is low. International guidelines for mainstreaming informed consent for genomic sequencing are necessary.
EUROPEAN JOURNAL OF CANCER
(2021)
Article
Medicine, General & Internal
Nischal Ranganath, Pritish K. Tosh, John O'Horo, Priya Sampathkumar, Matthew J. Binnicker, Aditya S. Shah
Summary: This article provides a comprehensive overview of the epidemiology, clinical manifestation, diagnosis, and treatment methods, as well as prevention and control strategies for monkeypox infection during the global outbreak.
MAYO CLINIC PROCEEDINGS
(2022)
Review
Endocrinology & Metabolism
Fasiha Kanwal, Jay H. Shubrook, Zobair Younossi, Yamini Natarajan, Elisabetta Bugianesi, Mary E. Rinella, Stephen A. Harrison, Christos Mantzoros, Kim Pfotenhauer, Samuel Klein, Robert H. Eckel, Davida Kruger, Hashem El-Serag, Kenneth Cusi
Summary: NAFLD and NASH are common conditions with significant management gaps between guidelines and practice; there is currently no unified global strategy. An international conference brought together experts to discuss and develop a comprehensive strategy for NAFLD/NASH care and called for a unified international public health response.
Article
Endocrinology & Metabolism
Fasiha Kanwal, Jay H. Shubrook, Zobair Younossi, Yamini Natarajan, Elisabetta Bugianesi, Mary E. Rinella, Stephen A. Harrison, Christos Mantzoros, Kim Pfotenhauer, Samuel Klein, Robert H. Eckel, Davida Kruger, Hashem El-Serag, Kenneth Cusi
Summary: NAFLD and NASH are common conditions with significant management gaps, lacking a single global guiding strategy. The American Gastroenterological Association, along with professional associations, convened an international conference to develop a comprehensive, unified strategy for primary care providers and specialists, calling for a unified international public health response to NAFLD and NASH.
METABOLISM-CLINICAL AND EXPERIMENTAL
(2021)
Editorial Material
Biochemical Research Methods
Kamila M. Bond, Margaret M. McCarthy, Joshua B. Rubin, Kristin R. Swanson
Summary: The commonly used omics databases primarily include male samples, limiting the understanding of the biology of sex differences.
Review
Pediatrics
Guddi Singh, Amaran Uthayakumar-Cumarasamy
Summary: The UK's 'cost of living crisis' has pushed millions into poverty, surpassing the impact of the global pandemic. This crisis is seen as a 'crisis of inequality', with health equity and social justice at stake. A 'social lens' is proposed for understanding the underlying causes of challenges like COLC, emphasizing the need for organized action both inside and outside of health systems to bring about necessary changes.
BMJ PAEDIATRICS OPEN
(2022)
Article
Psychology, Developmental
Eileen T. Crehan, Jessica Rocha, Simone Dufresne
Summary: This study compared the use of eleven potential sources of sexuality and relationship education (SRE) across nine content areas among autistic and neurotypical adults in the United States. Findings showed differences in source use, particularly in consulting same-aged peers and romantic partners. High internet use was consistent across all groups, indicating a need for improving access to SRE based on existing trends.
JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS
(2022)
Editorial Material
Biochemistry & Molecular Biology
Marta Rodriguez-Martinez, Jens Nielsen, Sam Dupont, Jessica Vamathevan, Beverley J. Glover, Lindsey C. Crosswell, Brendan Rouse, Ben F. Luisi, Chris Bowler, Susan M. Gasser, Detlev Arendt, Tobias J. Erb, Victor de Lorenzo, Edith Heard, Kiran Raosaheb Patil
Summary: Molecular biology has great potential in addressing climate change and biodiversity loss, but it is currently not well incorporated into strategies. We call for a community-wide action to bring molecular biology to the forefront of climate change solutions.
Article
Medicine, Research & Experimental
Ariane Rocha Bartolomeu, Yahima Frion-Herrera, Livia Matsumoto da Silva, Graziela Gorete Romagnoli, Deilson Elgui de Oliveira, Jose Mauricio Sforcin
BIOMEDICINE & PHARMACOTHERAPY
(2016)
Review
Biochemistry & Molecular Biology
Deilson Elgui de Oliveira, Barbara G. Muller-Coan, Joseph S. Pagano
TRENDS IN MICROBIOLOGY
(2016)
Article
Materials Science, Multidisciplinary
William de Melo Silva, Camila Amorim Ribeiro, Cleiton Silva Marques, Americo Sheitiro Tabata, Margarida Juri Saeki, Leonardo Iusuti Medeiros, Deilson Elgui de Oliveira
MATERIALS RESEARCH-IBERO-AMERICAN JOURNAL OF MATERIALS
(2017)
Article
Chemistry, Applied
Mirella Rossitto Zanutto-Elgui, Jose Cavalcante Souza Vieira, Debora Zanoni do Prado, Marilia Afonso Rabelo Buzalaf, Pedro de Magalhaes Padilha, Deilson Elgui de Oliveira, Luciana Francisco Fleuri
Article
Veterinary Sciences
Lidianne N. Monteiro, Breno S. Salgado, Deilson E. Oliveira, Luis G. Rivera-Calderon, Luis M. Montoya-Florez, Paula Sanctis, Noeme S. Rocha
PESQUISA VETERINARIA BRASILEIRA
(2020)
Editorial Material
Oncology
Patricia P. Reis, Wan L. Lam, Deilson Elgui de Oliveira
FRONTIERS IN ONCOLOGY
(2021)
Review
Oncology
Brunno Felipe R. Caetano, Beatrice Adrianne S. Jorge, Barbara Grasiele Mueller-Coan, Deilson Elgui de Oliveira
Summary: EBV is a gamma-herpesvirus linked to various human cancers, with its miRNAs modulating carcinogenesis and serving as potential markers for monitoring EBV-associated cancers.
Article
Multidisciplinary Sciences
Rafael Dezen Gaiolla, Marcelo Padovani de Toledo Moraes, Deilson Elgui de Oliveira
Summary: The study evaluated SNPs in genes encoding key cytokines in Hodgkin lymphoma and found that certain genotypes were associated with prognostic parameters in cHL patients. This study also described the association of SNP/iNFKB1 with clinical features of the disease for the first time.
Article
Genetics & Heredity
Barbara G. Mueller Coan, Ethel Cesarman, Marcio Luis Acencio, Deilson Elgui de Oliveira
Summary: This study evaluated the effects of LMP1 derived from different strains of EBV on miRNA regulation in nasopharyngeal cells. The results showed that different strains of LMP1 led to differential expression of specific miRNAs, and in silico analysis provided insights into the molecular effects of LMP1 expression on cellular processes and signaling pathways.
Review
Biochemistry & Molecular Biology
Alison Felipe Bordini Biggi, Deilson Elgui de Oliveira
Summary: The Epstein-Barr Virus (EBV) is involved in the development of various human cancers and may interfere with immune checkpoint molecules. This has implications for the clinical management of EBV-associated malignancies.
Letter
Virology
Deilson Elgui De Oliveira
JOURNAL OF MEDICAL VIROLOGY
(2023)
Meeting Abstract
Oncology
Brunno F. Caetano, Barbara G. Muller-Coan, Rafael L. Coan, Bruno E. Fantinatti, Deilson E. de Oliveira
Review
Oncology
Barbara Grasiele Mueller-Coan, Brunno Felipe Ramos Caetano, Joseph Stephen Pagano, Deilson Elgui de Oliveira
Meeting Abstract
Oncology
Barbara Grasiele Mueller-Coan, Ethel Cesarman, Deilson Elgui De Oliveira
Review
Oncology
Xinru Zhou, Yin Jia, Chuanbin Mao, Shanrong Liu
Summary: Small extracellular vesicles (sEVs), such as exosomes, have emerged as crucial targets for liquid biopsy and promising drug delivery vehicles in tumor progression. They can serve as biomarkers for tumor diagnosis and as drug carriers for cancer treatment.
Article
Oncology
Ruochan Chen, Ju Zhu, Xiao Zhong, Jie Li, Rui Kang, Daolin Tang
Summary: The interplay between autophagy and apoptosis plays a crucial role in tumorigenesis and cancer therapy, with HMGB1 serving as a key regulator in these processes.
Article
Oncology
Zongfu Pan, Xixuan Lu, Tong Xu, Jinming Chen, Lisha Bao, Ying Li, Yingying Gong, Yulu Che, Xiaozhou Zou, Zhuo Tan, Ping Huang, Minghua Ge
Summary: This study uncovered the emerging role of HN1 in promoting dedifferentiation of anaplastic thyroid cancer (ATC) cells. HN1 negatively regulated the thyroid differentiation markers and had an inhibitory effect on the transcriptional activation of CTCF, thereby influencing the chromatin accessibility of thyroid differentiation genes.
Article
Oncology
Yi Qin, Shengjun Xiong, Jun Ren, Gautam Sethi
Summary: Autophagy plays an important regulatory role in glioblastoma, and its dysregulation can lead to drug resistance and radioresistance. It also affects stem cell characteristics, overall growth, and metastasis. Therefore, autophagy is a promising target for glioblastoma therapy.
Article
Oncology
Katsuya Nagaoka, Xuewei Bai, Dan Liu, Kevin Cao, Joud Mulla, Chengcheng Ji, Hongze Chen, Muhammad Azhar Nisar, Amalia Bay, William Mueller, Grace Hildebrand, Jin-Song Gao, Shaolei Lu, Hiroko Setoyama, Yasuhito Tanaka, Jack R. Wands, Chiung-Kuei Huang
Summary: This study found that serum 2-OG levels in cholangiocarcinoma patients are associated with the effectiveness of chemotherapy. Patients with progressive disease showed significantly higher levels of serum 2-OG compared to stable disease and partial response patients. The study also revealed that overexpression of ASPH mimics the effects of 2-OG, and knockdown of ASPH improves chemotherapy. Targeting ASPH enhances the effects of chemotherapy by modulating ATM and ATR, two key regulators of DDRs.
