Article
Chemistry, Applied
Zahra Khoshbin, Marzieh Moeenfard, Khalil Abnous, Seyed Mohammad Taghdisi
Summary: A simple aptasensor embedded in a micropipette tip is developed for label-free monitoring of acrylamide. The aptasensor utilizes the formation of a triple-helix molecular switch structure to induce the aggregation of gold nanoparticles. A smartphone imaging readout strategy enables the quantification of acrylamide based on the color change of the solution inside the micropipette tip. This aptasensor shows good selectivity and can successfully quantify acrylamide in various food samples.
Article
Chemistry, Analytical
Xiaoyan Yang, Rong Huang, Lulu Xiong, Feng Chen, Wei Sun, Ling Yu
Summary: A novel colorimetric aptasensor was developed to detect ochratoxin A (OTA) by utilizing charge effect-assisted silver enhancement. Gold nanoparticles (AuNPs) were used as carriers of aptamers tagged with a positively charged tetramethylrhodamine (TAMRA), which catalyzed silver reduction and deposition. The TAMRA attracted and retained the silver lactate around the AuNPs due to the attraction between positive and negative charges, increasing the chance of AuNP-catalyzed silver reduction. The charge effect-assisted silver enhancement was confirmed by tagging aptamers of different base pair lengths with TAMRA. The as-prepared OTA aptasensor exhibited a working range of 1 x 10(2)-1 x 10(6) pg mL(-1) and a detection limit of 28.18 pg mL(-1). It was successfully applied to determine OTA in actual samples with satisfactory results.
Review
Biochemical Research Methods
Farahnaz Behzad, Azam Samadi, Elaheh Rahimpour, Mahdi Adabi, Abolghasem Jouyban
Summary: Aptasensors have gained popularity due to their excellent particularity, selectivity, and responsiveness. When combined with gold nanoparticles (AuNPs), these biosensors can detect various chemical and biological molecules. The changing color of AuNPs provides a simple explanation for the sensor's response. This review summarizes the recent developments in AuNP-based colorimetric aptasensors for sensing different analytes, discusses their uses, challenges, and prospects for forming new aptasensors.
Article
Fisheries
Parisa Etedali, Mandana Behbahani, Hassan Mohabatkar, Ghasem Dini
Summary: A rapid colorimetric aptasensor with high selectivity and sensitivity was developed for the detection of white spot syndrome virus (WSSV). The designed aptamer showed good specificity to WSSV and could detect as low as 10^4 copies of WSSV using naked eyes. This study demonstrated excellent potential for the rapid visual colorimetric detection of WSSV in aquaculture shrimp farming.
Article
Chemistry, Multidisciplinary
Yuan Liu, Taotao Li, Gaojian Yang, Yan Deng, Xianbo Mou, Nongyue He
Summary: The authors developed a simple gold nanoparticles-based colorimetric biosensor for chlorpyrifos detection, utilizing an aptamer as the capture probe. The method exhibited excellent sensitivity and reliable detection performance, making it a promising tool for chlorpyrifos detection in water and agricultural products.
CHINESE CHEMICAL LETTERS
(2022)
Review
Chemistry, Medicinal
Marjan Majdinasab, Jean Louis Marty
Summary: The early diagnosis of diseases is crucial for effective treatment, and biomarkers offer great potential in this area. Aptamer-based biosensors, with their high sensitivity and selectivity, have emerged as a promising diagnostic tool. Electrochemical aptasensors have attracted significant attention due to their high sensitivity and accuracy in biomarker detection.
Article
Chemistry, Applied
Reza Mahjub, Omid Heydari Shayesteh, Katayoun Derakhshandeh, Akram Ranjbar, Fereshteh Mehri, Ali Heshmati
Summary: In this study, a novel colorimetric bioassay method was developed for the sensitive determination of tobramycin. The method utilizes aptamers and silver nanoparticles to induce aggregation and visible color change in the presence of tobramycin, allowing for quantitative analysis. This method offers high sensitivity and visual detection.
Review
Environmental Sciences
Abolfazl Nourizad, Saeed Golmohammadi, Ayuob Aghanejad, Mohammad Reza Tohidkia
Summary: Vascular endothelial growth factor (VEGF) is a cytokine that regulates vascular formation during angiogenesis and is overexpressed in various tumors, making its real-time detection and quantification essential for clinical diagnosis and treatment. Aptamer-based sensors, which combine aptamers with biological molecules, improve the detection ability of VEGF. Aptamers are suitable recognition agents for sensitive and reproducible aptasensors (Apt-sensors) due to their low immunogenicity, simple chemical modification, and high resistance to denaturation.
ENVIRONMENTAL RESEARCH
(2023)
Article
Agriculture, Multidisciplinary
Xunjiao Wei, Pengfei Ma, Khan Imran Mahmood, Yin Zhang, Zhouping Wang
Summary: Aflatoxin M1 (AFM1), a highly toxic secondary metabolite of Aspergillus spp., is widely present in food matrices. The study utilized graphene oxide-SELEX (GO-SELEX) to screen and identify aptamer 9 as the best candidate for AFM1. A colorimetric sensor based on the aptamer was constructed and showed good linearity for AFM1 detection in the range of 0.5-500.0 ng/mL with a detection limit of 0.50 ng/mL. The sensor was successfully used for the detection of AFM1 in milk powder samples with a detection recovery of 92.8-105.2%. This study provides a reference for AFM1 detection in food.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2023)
Review
Chemistry, Analytical
Jidong Tang, Xiaoqi Tao
Summary: This paper provides a summary of the research on AuNP-based aptasensors for detecting kanamycin in food products. The study reveals that the nonspecific adsorption of kanamycin on AuNPs can negatively impact the accuracy of detection. Therefore, it is necessary to reconsider the guiding principles for future research on aptasensors and provide improvement methods to avoid nonspecific adsorption.
MICROCHEMICAL JOURNAL
(2023)
Article
Chemistry, Analytical
Xiuping Li, ZhiJuan Qian, Rui Chang, Chifang Peng, Zhengjun Xie, Zhouping Wang
Summary: A novel Apt-LFA method for kanamycin detection in honey was developed, improving the hybridization speed and efficiency of nucleic acid. The method showed a low detection limit and high recovery rate, making it a promising tool for kanamycin monitoring in honey.
Article
Chemistry, Analytical
Saipriya Ramalingam, Christopher M. Collier, Ashutosh Singh
Summary: Antibiotics are widely used in veterinary science to promote animal health and feed efficiency, but concerns arise due to the potential residues in milk. Therefore, quick and reliable testing methods are essential to ensure the safety of the produced milk.
Article
Chemistry, Multidisciplinary
Chadamas Sakonsinsiri, Theerapong Puangmali, Kaniknun Sreejivungsa, Sireemas Koowattanasuchat, Raynoo Thanan, Apiwat Chompoosor, Sirinan Kulchat, Paiboon Sithithaworn
Summary: In this study, a simple and rapid colorimetric method for detecting 8-oxo-dG concentration in urine was developed using cysteamine-stabilised gold nanoparticles. The method showed excellent sensing ability and had a detection limit as low as 10.3 nM. The results also demonstrated the potential of this method for on-site analysis of 8-oxo-dG in urine.
Article
Biotechnology & Applied Microbiology
Fernanda Raquel Wust Schmitz, Karina Cesca, Alexsandra Valerio, Debora de Oliveira, Dachamir Hotza
Summary: Novel rapid methodologies involving colorimetric biosensors and gold nanoparticles have been developed for the detection of bacteria, specifically Pseudomonas aeruginosa. The biosensor relies on the color change of gold nanoparticles induced by NaCl after incubation with bacteria and aptamer binding. The optimized conditions for detection were found to be 5 μM aptamer concentration and 200 mM of NaCl. The detection limit for P. aeruginosa was 10(5) CFU mL(-1) by the naked eye and 10(4) CFU mL(-1) by UV-Vis spectrometry.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
(2023)
Review
Biochemistry & Molecular Biology
Zahra Khoshbin, Neda Shakour, Mehrdad Iranshahi, Alexandra E. Butler, Amirhossein Sahebkar
Summary: Diabetes is a chronic disease caused by insufficient insulin secretion, resulting in high blood glucose levels. It is a global health concern that can lead to serious complications if left untreated. Biosensors, particularly aptasensors, offer a promising solution for diabetes diagnosis.
CURRENT MEDICINAL CHEMISTRY
(2023)
Article
Biochemical Research Methods
Bakhtyar Sepehri, Nematollah Omidikia, Mohsen Kompany-Zareh, Raouf Ghavami
COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING
(2018)
Article
Chemistry, Multidisciplinary
B. Sepehri, R. Ghavami
SAR AND QSAR IN ENVIRONMENTAL RESEARCH
(2019)
Article
Chemistry, Analytical
Omid Heydari Shayesteh, Raouf Ghavami
Article
Chemistry, Analytical
Shadab Faham, Raouf Ghavami, Hamed Golmohammadi, Gholamreza Khayatian
Article
Chemistry, Analytical
Shadab Faham, Hamed Golmohammadi, Raouf Ghavami, Gholamreza Khayatian
ANALYTICA CHIMICA ACTA
(2019)
Article
Chemistry, Analytical
Zolaikha Rasouli, Raouf Ghavami
Article
Chemistry, Multidisciplinary
Zolaikha Rasouli, Raouf Ghavami
Review
Chemistry, Multidisciplinary
Tina Naghdi, Shadab Faham, Tohid Mahmoudi, Nahid Pourreza, Raouf Ghavami, Hamed Golmohammadi
Article
Chemistry, Analytical
Zolaikha Rasouli, Raouf Ghavami
Summary: A simple and efficient sensor array based on nanoaggregation of curcumin was developed for the identification and quantification of metal ions. The nanocurcumin was characterized by UV-Vis, TEM, and FT-IR for distinguishing metal ions through UV-Vis absorbance changes.
Article
Chemistry, Multidisciplinary
Fereydoun Sadeghi, Abbas Afkhami, Tayyebe Madrakian, Raouf Ghavami
Summary: A study on anthracycline derivatives was conducted to establish a quantitative structure-activity relationship model. The model, developed using a genetic algorithm and multiple linear regression, demonstrated high stability and robustness in predicting inhibitory concentrations of analogs. The model was successfully generalized to other compounds, aiding in the selection of potent drug candidates.
Article
Chemistry, Analytical
Omid Heydari Shayesteh, Abolfazl Ghafouri Khosroshahi
ANALYTICAL METHODS
(2020)
Article
Biochemistry & Molecular Biology
Roya Ahmadi, Bakhtyar Sepehri, Raouf Ghavami
JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION
(2019)
Article
Spectroscopy
Zh. E. Ozbekova, A. A. Abdyldaev, A. A. Kulmyrzaev
Summary: This study compared two drying methods for cow and yak muscles, finding that freeze drying caused less discoloration. Additionally, analysis of fluorescence spectra allowed for accurate prediction of chemical composition and color characteristics of the muscles.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Leo Mandic, Ivan Ljubic, Iva Dzeba
Summary: In this study, a combined experimental and computational approach was used to investigate the photoexcitation and photodegradation mechanisms of Doxazosin (DOX). The results provide valuable insights into the primary events following the photoexcitation of DOX and its potential applications.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Xiufeng Wang, Yao Jin, Wenhui Ai, Siqi Wang, Zhiqing Zhang, Ting Zhou, Fang Wang, Guodong Zhang
Summary: This study successfully synthesized near infrared fluorescence Ag2S quantum dots (QDs) and developed a dual-mode sensor for sulfide anion using the excellent oxidase-like characteristics of manganese dioxide (MnO2) nanosheets. The sensor showed a wider detection range, higher sensitivity, and shorter reaction time, making it suitable for highly selective detection of sulfide in different concentration ranges.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Yafei Li, Yanming Ma, Chuantao Zheng, Di Yu, Lien Hu, Shuo Yang, Fang Song, Yadan Li, Shuanghai Liu, Zhanrui Zhang, Yu Zhang, Yiding Wang, Frank K. Tittel
Summary: To effectively monitor gas explosion and coal spontaneous combustion in coal mine, an intrinsically safe and explosion-proof dual-gas sensor system was developed for methane (CH4) and carbon monoxide (CO) measurement. The system achieved different measurement ranges using laser scanning and gas cells, and improved stability and accuracy through gas pre-treatment and temperature compensation algorithm.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Pei-Rong Chen, Li-Kang Chu
Summary: In this study, the hydrates of glyoxal were investigated using infrared absorption spectrometry. The results showed that at low concentrations, glyoxal mainly exists as monomeric dihydrate. These findings provide suitable detection windows for further research on the roles of glyoxal and its hydrates in atmospheric and aerosol chemistry, as well as the relevant reaction kinetics.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Nichole O'Neill, Thamires A. Lima, Fabio Furlan Ferreira, Nicolas J. Alvarez, Reinhard Schweitzer-Stenner
Summary: This study determines the main fibril axis of GHG gel-forming fibrils using various techniques and compares the results with simulated data. The analysis suggests that the hydrophobic xz-surfaces of GHG fibrils could be a good target for the adsorption of hydrophobic drugs.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Mengyuan Liu, Hanchuang Zhu, Yikun Fang, Caiyun Liu, Xinke Li, Xiaohui Zhang, Lixue Ma, Kun Wang, Miaohui Yu, Wenlong Sheng, Baocun Zhu
Summary: ABHS is an efficient fluorescent probe that can accurately and sensitively detect Al3+ with strong resistance to interference. It also demonstrates excellent detection and imaging capabilities in complex real samples.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Ahmed S. El-Shafie, Evana Rahman, Yasser Gadelhak, Rehab Mahmoud, Marwa El-Azary
Summary: The recycling of waste mandarin peels into biochar (MRBC) has been used as a high performance and cost-effective adsorbent for treating polluted wastewater effluents. Batch adsorption studies were conducted to analyze the adsorption competency of MRBC on two dyes, methylene blue (MB) and basic fuchsin (BF), either in individual solutions or binary combinations. The results showed that MRBC was capable of effectively removing a high percentage of both dyes. However, the adsorption capacity decreased when the dyes were combined. The cost estimation of MRBC production and wastewater treatment indicated that both were relatively low.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Anindita Bhatta, Jahnabi Upadhyaya, Dipak Chamlagai, Lincoln Dkhar, Pynskhemborlang T. Phanrang, Mohan Rao Kollipara, Sivaprasad Mitra
Summary: Derivatives of thiazole-pyrazole fused benzo-coumarin compounds were synthesized and their photophysical properties were investigated. The synthesized coumarin compounds showed potential as therapeutic agents for Alzheimer's disease, inhibiting acetylcholinesterase activity. The presence of human serum albumin was found to affect the inhibition activity.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Yongwei Duan, Quancheng Liu, Yiju Zhu, Qi Zhang, Xiaohui Duan, Hu Deng, Liping Shang
Summary: In this study, the phase transition of CL-20 was observed using terahertz spectroscopy, and quantum chemical calculations were employed to analyze the vibrations. The results indicated changes in the vibrations of CL-20 before and after phase transition.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Yuefeng Gao, Sai Xu, Baojiu Chen
Summary: This study synthesized Cs2NaInCl6 nanocrystals co-doped with Sb3+ and Tb3+ ions as probes for copper ions detection in lubricating oil. The introduction of Sb3+ effectively reduced the band gap of the host material and enabled energy transfer pathway for Tb3+ emission. The doped Tb3+ ions resulted in the suppression of emission due to electron transfer. The Cs2NaInCl6: 2.5 %Sb3+, 40 %Tb3+ NCs exhibited superior sensitivity and selectivity for copper ions detection.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Yu Liu, Yue Zhang, Changyao Liu, Ce Wang, Baocai Xu, Li Zhao
Summary: A highly sensitive detection platform for heparin was developed using a cationic fluorescent dye (cresyl violet acetate) as a fluorescence probe. The platform demonstrated high selectivity towards heparin and achieved detection in both HEPES solution and serum.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Lopamudra Roy, Nivedita Pan, Susmita Mondal, Ria Ghosh, Md. Nur Hasan, Neha Bhattacharyya, Soumendra Singh, Kallol Bhattacharyya, Arpita Chattopadhyay, Samir Kumar Pal
Summary: The study focuses on the interaction between reactive oxygen species (ROS) and a spectroscopic probe called Rose Bengal (RB), encapsulated in nanoscopic sodium dodecyl sulphate (SDS) micelles and entrapped in microscopic nylon 66 solid matrix. The research demonstrates efficient interaction between ROS and RB-SDS, and investigates the mechanism of hydroxyl radicals generation. Based on these findings, a prototype device utilizing RB embedded in a nylon thin film for quantification of ROS in extracellular fluids and food materials was developed.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Xiaosong Sun, Qihao Cui, Wenyue Dong, Qian Duan, Teng Fei
Summary: Conjugated porous polymers (CPPs) are promising sensing materials and their application in aqueous media is limited. In this study, we synthesized CPPs with porous structure and prepared nanoparticles, enabling efficient photoluminescence sensing of nitroaromatic explosives in aqueous phase.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Maria Cristina Caggiani, Germana Barone, Paolo Mazzoleni
Summary: Raman spectroscopy is commonly used for studying glassy materials in cultural heritage, but it is more difficult to interpret the spectra and apply the technique with portable instruments. In contrast, diffuse reflectance infrared Fourier transform spectroscopy (DRIFTS) can be used in archaeometric investigations as it is portable and non-invasive. However, there is limited application of this technique to historical glasses. This exploratory work demonstrates the potential of DRIFTS, in combination with portable X-ray Fluorescence (pXRF) and EDS microanalyses, for studying the composition and alteration of glass samples in cultural heritage.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)